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Insulin–Dendrimer Nanocomplex for Multi‐Day Glucose‐Responsive Therapy in Mice and Swine (Adv. Mater. 5/2024)
Xian, Sijie, Xiang, Yuanhui, Liu, Dongping, Fan, Bowen, Mitrová, Katarína, Ollier, Rachel C., Su, Bo, Alloosh, Muhammad Ali, Jiráček, Jiří, Sturek, Michael, Alloosh, Mouhamad, Webber, Matthew J.
Published in Advanced materials (Weinheim) (01.02.2024)
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Insulin–Dendrimer Nanocomplex for Multi‐Day Glucose‐Responsive Therapy in Mice and Swine
Xian, Sijie, Xiang, Yuanhui, Liu, Dongping, Fan, Bowen, Mitrová, Katarína, Ollier, Rachel C., Su, Bo, Alloosh, Muhammad Ali, Jiráček, Jiří, Sturek, Michael, Alloosh, Mouhamad, Webber, Matthew J.
Published in Advanced materials (Weinheim) (01.02.2024)
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Functional stapled fragments of human preptin of minimised length
Lubos, Marta, Mrázková, Lucie, Gwozdiaková, Petra, Pícha, Jan, Bud šínský, Miloš, Jirá ek, Ji í, Kaminský, Jakub, áková, Lenka
Published in Organic & biomolecular chemistry (23.03.2022)
Published in Organic & biomolecular chemistry (23.03.2022)
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Combinatorial Libraries of Bipodal Binders of the Insulin Receptor
Selicharová, Irena, Fabre, Benjamin, Soledad Garre Hernández, María, Lubos, Marta, Pícha, Jan, Voburka, Zdeněk, Mitrová, Katarína, Jiráček, Jiří
Published in ChemMedChem (03.06.2024)
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Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation
Kertisová, Anna, Žáková, Lenka, Macháčková, Kateřina, Marek, Aleš, Šácha, Pavel, Pompach, Petr, Jiráček, Jiří, Selicharová, Irena
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Published in Open biology (08.11.2023)
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Characterization of insulin crystalline form in isolated β-cell secretory granules
Asai, Seiya, Moravcová, Jana, Žáková, Lenka, Selicharová, Irena, Hadravová, Romana, Brzozowski, Andrzej Marek, Nováček, Jiří, Jiráček, Jiří
Published in Open biology (01.12.2022)
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Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications
Lubos, Marta, Pícha, Jan, Selicharová, Irena, Žák, Jíří, Buděšínský, Miloš, Mitrová, Katarína, Žáková, Lenka, Jiráček, Jiří
Published in Journal of peptide science (01.07.2023)
Published in Journal of peptide science (01.07.2023)
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Lin, Jingjing, Selicharová, Irena, Mitrová, Katarína, Fabre, Benjamin, Miriyala, Vijay Madhav, Lepšík, Martin, Jiráček, Jiří, Hernández, María Soledad Garre
Published in Journal of peptide science (01.04.2023)
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Insulin and Insulin-like Growth Factor II Differentially Regulate Endocytic Sorting and Stability of Insulin Receptor Isoform A
Morcavallo, Alaide, Genua, Marco, Palummo, Angela, Kletvikova, Emilia, Jiracek, Jiri, Brzozowski, Andrzej M., Iozzo, Renato V., Belfiore, Antonino, Morrione, Andrea
Published in The Journal of biological chemistry (30.03.2012)
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Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain
Hexnerová, Rozálie, Křížková, Květoslava, Fábry, Milan, Sieglová, Irena, Kedrová, Kateřina, Collinsová, Michaela, Ullrichová, Pavlína, Srb, Pavel, Williams, Christopher, Crump, Matthew P., Tošner, Zdeněk, Jiráček, Jiří, Veverka, Václav, Žáková, Lenka
Published in The Journal of biological chemistry (30.09.2016)
Published in The Journal of biological chemistry (30.09.2016)
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A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding
Chrudinová, Martina, Žáková, Lenka, Marek, Aleš, Socha, Ondřej, Buděšínský, Miloš, Hubálek, Martin, Pícha, Jan, Macháčková, Kateřina, Jiráček, Jiří, Selicharová, Irena
Published in The Journal of biological chemistry (26.10.2018)
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Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2
Pompach, Petr, Viola, Cristina M, Radosavljević, Jelena, Lin, Jingjing, Jiráček, Jiří, Brzozowski, Andrzej M, Selicharová, Irena
Published in Frontiers in endocrinology (Lausanne) (09.10.2019)
Published in Frontiers in endocrinology (Lausanne) (09.10.2019)
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Multipodal insulin mimetics built on adamantane or proline scaffolds
Hajduch, Jan, Fabre, Benjamin, Klopp, Benjamin, Pohl, Radek, Buděšínský, Miloš, Šolínová, Veronika, Kašička, Václav, Köprülüoglu, Cemal, Eyrilmez, Saltuk Mustafa, Lepšík, Martin, Hobza, Pavel, Mitrová, Katarína, Lubos, Marta, Hernández, María Soledad Garre, Jiráček, Jiří
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The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels
Dzianová, Petra, Asai, Seiya, Chrudinová, Martina, Kosinová, Lucie, Potalitsyn, Pavlo, Šácha, Pavel, Hadravová, Romana, Selicharová, Irena, Kříž, Jan, Turkenburg, Johan P, Brzozowski, Andrzej Marek, Jiráček, Jiří, Žáková, Lenka
Published in Open biology (21.10.2020)
Published in Open biology (21.10.2020)
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Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface
Antolíková, Emília, Žáková, Lenka, Turkenburg, Johan P., Watson, Christopher J., Hančlová, Ivona, Šanda, Miloslav, Cooper, Alan, Kraus, Tomáš, Brzozowski, A. Marek, Jiráček, Jiří
Published in The Journal of biological chemistry (21.10.2011)
Published in The Journal of biological chemistry (21.10.2011)
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Mono-N-acyl-2,6-diaminopimelic acid derivatives: Analysis by electromigration and spectroscopic methods and examination of enzyme inhibitory activity
Hlaváček, Jan, Vítovcová, Miloslava, Sázelová, Petra, Pícha, Jan, Vaněk, Václav, Buděšínský, Miloš, Jiráček, Jiří, Gillner, Danuta M., Holz, Richard C., Mikšík, Ivan, Kašička, Václav
Published in Analytical biochemistry (15.12.2014)
Published in Analytical biochemistry (15.12.2014)
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Efficient synthesis of phosphonodepsipeptides derived from norleucine
Pícha, Jan, Buděšínský, Miloš, Hančlová, Ivona, Šanda, Miloslav, Fiedler, Pavel, Vaněk, Václav, Jiráček, Jiří
Published in Tetrahedron (01.08.2009)
Published in Tetrahedron (01.08.2009)
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S -Alkylated Homocysteine Derivatives: New Inhibitors of Human Betaine-Homocysteine S-Methyltransferase
Jiracek, Jiri, Collinsova, Michaela, Rosenberg, Ivan, Budesinsky, Milos, Protivinska, Eva, Netusilova, Hana, Garrow, Timothy A
Published in Journal of medicinal chemistry (29.06.2006)
Published in Journal of medicinal chemistry (29.06.2006)
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