Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
Xing, Jing, Zhang, Rukang, Jiang, Xiangrui, Hu, Tianwen, Wang, Xinjun, Qiao, Gang, Wang, Junjian, Yang, Fengling, Luo, Xiaomin, Chen, Kaixian, Shen, Jingshan, Luo, Cheng, Jiang, Hualiang, Zheng, Mingyue
Published in European journal of medicinal chemistry (01.02.2019)
Published in European journal of medicinal chemistry (01.02.2019)
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Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from o -bromoarylamine and nitriles
Bonku, Emmanuel Mintah, Qin, Hongjian, Odilov, Abdullajon, Abduahadi, Safomuddin, Guma, Samuel Desta, Yang, Feipu, Zhu, Fuqiang, Aisa, Haji A, Shen, Jingshan
Published in RSC advances (21.02.2024)
Published in RSC advances (21.02.2024)
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Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
Li, Xiaomei, Zhang, Hui, Dong, Sanfeng, Gao, Xuejie, Sun, Haiguo, Zhou, Zhaoyin, Hu, Ke, Guo, Shushan, Zhang, Qikai, Guo, Zhufeng, Jacob Bunu, Samuel, Zhu, Jianming, Li, Bo, Zhang, Yong, Shen, Jingshan, Akber Aisa, Haji, Xu, Zhijian, Cai, Haiyan, Shi, Jumei, Zhu, Weiliang
Published in Bioorganic & medicinal chemistry (01.09.2024)
Published in Bioorganic & medicinal chemistry (01.09.2024)
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Design, synthesis, in vitro evaluation of a new pyrrolothiazolopyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
Zeng, Yan, Nie, Lifei, Liu, Liu, Niu, Chao, Li, Yi, Bozorov, Khurshed, Zhao, Jiangyu, Shen, Jingshan, Haji Akber Aisa
Published in Journal of heterocyclic chemistry (01.06.2022)
Published in Journal of heterocyclic chemistry (01.06.2022)
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Pharmacokinetics-Driven Optimization of 4(3H)‑Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
Wang, Zhen, Jiang, Xiangrui, Zhang, Xianglei, Tian, Guanghui, Yang, Rulei, Wu, Jianzhong, Zou, Xiaoli, Liu, Zheng, Yang, Xiaojun, Wu, Chunhui, Shi, Jing, Li, Jianfeng, Suo, Jin, Wang, Yu, Zhang, Rongxia, Xu, Zhijian, Gong, Xudong, He, Yang, Zhu, Weiliang, Aisa, Haji Akber, Jiang, Hualiang, Xu, Yechun, Shen, Jingshan
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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An Improved Synthesis of 4‑(1-Piperazinyl)benzo[b]thiophene Dihydrochloride
Wu, Chunhui, Chen, Weiming, Jiang, Dehui, Jiang, Xiangrui, Shen, Jingshan
Published in Organic process research & development (17.04.2015)
Published in Organic process research & development (17.04.2015)
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Facile synthesis of 2-C-methyl-d-arabino-γ-1,4-lactones and mechanism study
Lv, Bingqing, Guo, Shuang, Zhu, Fuqiang, Hu, Tianwen, Guo, Qi, Lin, Haixia, Xie, Yuanchao, Shen, Jingshan
Published in Tetrahedron letters (11.04.2018)
Published in Tetrahedron letters (11.04.2018)
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A novel synthesis of tetrahydrocortisone 3-glucuronide
Zhang, Yan, Zhang, Suqing, Li, Rui, Shen, Jingshan, Jiang, Xiangrui, Aisa, Haji A.
Published in Journal of carbohydrate chemistry (02.01.2022)
Published in Journal of carbohydrate chemistry (02.01.2022)
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Oxidative Aromatization of 3,4-Dihydroquinolin-2(1H)‑ones to Quinolin-2(1H)‑ones Using Transition-Metal-Activated Persulfate Salts
Chen, Weiming, Sun, Changliang, Zhang, Yan, Hu, Tianwen, Zhu, Fuqiang, Jiang, Xiangrui, Abame, Melkamu Alemu, Yang, Feipu, Suo, Jin, Shi, Jing, Shen, Jingshan, Aisa, Haji A
Published in Journal of organic chemistry (05.07.2019)
Published in Journal of organic chemistry (05.07.2019)
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The mimics of Nε-acyl-lysine derived from cysteine as sirtuin inhibitors
Wang, Chun, Wang, Fang, Chen, Xiaoxue, Zou, Yefang, Zhu, Hong, Zhao, Qingjie, Shen, Jingshan, Li, Yan, Li, Yongjun, He, Bin
Published in Bioorganic & medicinal chemistry letters (01.08.2018)
Published in Bioorganic & medicinal chemistry letters (01.08.2018)
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The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
Gao, George F, Li, Qing, Qi, Jianxun, Zhang, Wei, Vavricka, Christopher J, Shi, Yi, Wei, Jinhua, Feng, Enguang, Shen, Jingshan, Chen, Jilong, Liu, Di, He, Jianhua, Yan, Jinghua, Liu, Hong, Jiang, Hualiang, Teng, Maikun, Li, Xuebing
Published in Nature structural & molecular biology (01.10.2010)
Published in Nature structural & molecular biology (01.10.2010)
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Sildenafil promotes adipogenesis through a PKG pathway
Zhang, Xiaodong, Ji, Jun, Yan, Guirui, Wu, Jingwei, Sun, Xiaoyun, Shen, Jingshan, Jiang, Hualiang, Wang, Heyao
Published in Biochemical and biophysical research communications (11.06.2010)
Published in Biochemical and biophysical research communications (11.06.2010)
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Practical and Highly Efficient Synthesis of Remdesivir from GS-441524
Hu, Tianwen, Zhu, Fuqiang, Xiang, Li, Shen, Jingshan, Xie, Yuanchao, Aisa, Haji A.
Published in ACS omega (09.08.2022)
Published in ACS omega (09.08.2022)
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Thermodynamic and Structural Characterization of Halogen Bonding in Protein–Ligand Interactions: A Case Study of PDE5 and Its Inhibitors
Ren, Jing, He, Yang, Chen, Wuyan, Chen, Tiantian, Wang, Guan, Wang, Zhen, Xu, Zhijian, Luo, Xiaomin, Zhu, Weiliang, Jiang, Hualiang, Shen, Jingshan, Xu, Yechun
Published in Journal of medicinal chemistry (24.04.2014)
Published in Journal of medicinal chemistry (24.04.2014)
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Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo-controlled, phase 1b trial
Wang, Fuxiang, Xiao, Wen, Tang, Yimin, Cao, Mengli, Shu, Dan, Asakawa, Tetsuya, Xu, Yechun, Jiang, Xiangrui, Zhang, Leike, Wang, Wei, Tang, Jianxing, Huang, Yuansheng, Yang, Yang, Yang, Yumei, Tang, Renhong, Shen, Jingshan, Lu, Hongzhou
Published in The Lancet regional health. Western Pacific (01.09.2023)
Published in The Lancet regional health. Western Pacific (01.09.2023)
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A Facile Route of Synthesis for Making Flibanserin
Yang, Feipu, Wu, Chunhui, Li, Zhiqiang, Tian, Guanghui, Wu, Jianzhong, Zhu, Fuqiang, Zhang, Jian, He, Yang, Shen, Jingshan
Published in Organic process research & development (16.09.2016)
Published in Organic process research & development (16.09.2016)
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Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect
Xu, Mingshuo, Wang, Yu, Yang, Feipu, Wu, Chunhui, Wang, Zhen, Ye, Bin, Jiang, Xiangrui, Zhao, Qingjie, Li, Jianfeng, Liu, Yongjian, Zhang, Junchi, Tian, Guanghui, He, Yang, Shen, Jingshan, Jiang, Hualiang
Published in European journal of medicinal chemistry (10.02.2018)
Published in European journal of medicinal chemistry (10.02.2018)
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Industry-Oriented Route Evaluation and Process Optimization for the Preparation of Brexpiprazole
Chen, Weiming, Suo, Jin, Liu, Yongjian, Xie, Yuanchao, Wu, Mingjun, Zhu, Fuqiang, Nian, Yifeng, Aisa, Haji A, Shen, Jingshan
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
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An improved synthesis of telmisartan the copper-catalyzed cyclization of -haloarylamidines
Zhang, Junchi, Li, Rui, Zhu, Fuqiang, Sun, Changliang, Shen, Jingshan
Published in RSC advances (03.04.2020)
Published in RSC advances (03.04.2020)
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