Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression
Lim, Kian Huat, Han, Zhou, Jeon, Hyun Yong, Kach, Jacob, Jing, Enxuan, Weyn-Vanhentenryck, Sebastien, Downs, Mikaela, Corrionero, Anna, Oh, Raymond, Scharner, Juergen, Venkatesh, Aditya, Ji, Sophina, Liau, Gene, Ticho, Barry, Nash, Huw, Aznarez, Isabel
Published in Nature communications (09.07.2020)
Published in Nature communications (09.07.2020)
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Journal Article
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
Jing, Enxuan, Emanuelli, Brice, Hirschey, Matthew D., Boucher, Jeremie, Lee, Kevin Y., Lombard, David, Verdin, Eric M., Kahn, C. Ronald
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2011)
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Journal Article
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
Hirschey, Matthew D, Shimazu, Tadahiro, Goetzman, Eric, Jing, Enxuan, Schwer, Bjoern, Lombard, David B, Grueter, Carrie A, Harris, Charles, Biddinger, Sudha, Ilkayeva, Olga R, Stevens, Robert D, Li, Yu, Saha, Asish K, Ruderman, Neil B, Bain, James R, Newgard, Christopher B
Published in Nature (London) (04.03.2010)
Published in Nature (London) (04.03.2010)
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Journal Article
SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
Hirschey, Matthew D., Shimazu, Tadahiro, Jing, Enxuan, Grueter, Carrie A., Collins, Amy M., Aouizerat, Bradley, Stančáková, Alena, Goetzman, Eric, Lam, Maggie M., Schwer, Bjoern, Stevens, Robert D., Muehlbauer, Michael J., Kakar, Sanjay, Bass, Nathan M., Kuusisto, Johanna, Laakso, Markku, Alt, Frederick W., Newgard, Christopher B., Farese, Robert V., Kahn, C. Ronald, Verdin, Eric
Published in Molecular cell (21.10.2011)
Published in Molecular cell (21.10.2011)
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Journal Article
Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation
ENXUAN JING, O'NEILL, Brian T, GIBSON, Bradford W, KAHN, C. Ronald, RARDIN, Matthew J, KLEINRIDDERS, André, ILKEYEVA, Olga R, USSAR, Siegfried, BAIN, James R, LEE, Kevin Y, VERDIN, Eric M, NEWGARD, Christopher B
Published in Diabetes (New York, N.Y.) (01.10.2013)
Published in Diabetes (New York, N.Y.) (01.10.2013)
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Journal Article
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
Biddinger, Sudha B, Haas, Joel T, Yu, Bian B, Bezy, Olivier, Jing, Enxuan, Zhang, Wenwei, Unterman, Terry G, Carey, Martin C, Kahn, C Ronald
Published in Nature medicine (01.07.2008)
Published in Nature medicine (01.07.2008)
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Journal Article
Hsp90β knockdown in DIO mice reverses insulin resistance and improves glucose tolerance
Jing, Enxuan, Sundararajan, Pragalath, Majumdar, Ishita Deb, Hazarika, Suwagmani, Fowler, Samantha, Szeto, Angela, Gesta, Stephane, Mendez, Armando J, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R
Published in Nutrition & metabolism (02.02.2018)
Published in Nutrition & metabolism (02.02.2018)
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Journal Article
Reduced voluntary activity precedes adult-onset obesity in Nhlh2 knockout mice
Coyle, Christopher A, Jing, Enxuan, Hosmer, Trina, Powers, J.Bradley, Wade, George, Good, Deborah J
Published in Physiology & behavior (01.11.2002)
Published in Physiology & behavior (01.11.2002)
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Journal Article
Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation
Schilling, Birgit, Rardin, Matthew J, MacLean, Brendan X, Zawadzka, Anna M, Frewen, Barbara E, Cusack, Michael P, Sorensen, Dylan J, Bereman, Michael S, Jing, Enxuan, Wu, Christine C, Verdin, Eric, Kahn, C Ronald, Maccoss, Michael J, Gibson, Bradford W
Published in Molecular & cellular proteomics (01.05.2012)
Published in Molecular & cellular proteomics (01.05.2012)
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Journal Article
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation
Kendrick, Agnieszka A, Choudhury, Mahua, Rahman, Shaikh M, McCurdy, Carrie E, Friederich, Marisa, Van Hove, Johan L K, Watson, Peter A, Birdsey, Nicholas, Bao, Jianjun, Gius, David, Sack, Michael N, Jing, Enxuan, Kahn, C Ronald, Friedman, Jacob E, Jonscher, Karen R
Published in Biochemical journal (01.02.2011)
Published in Biochemical journal (01.02.2011)
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Journal Article
Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway
Townsend, Kristy L, Suzuki, Ryo, Huang, Tian Lian, Jing, Enxuan, Schulz, Tim J, Lee, Kevin, Taniguchi, Cullen M, Espinoza, Daniel O, McDougall, Lindsay E, Zhang, Hongbin, He, Tong-Chuan, Kokkotou, Efi, Tseng, Yu-Hua
Published in The FASEB journal (01.05.2012)
Published in The FASEB journal (01.05.2012)
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Journal Article
Hsp90[beta] knockdown in DIO mice reverses insulin resistance and improves glucose tolerance
Jing, Enxuan, Sundararajan, Pragalath, Majumdar, Ishita Deb, Hazarika, Suwagmani, Fowler, Samantha, Szeto, Angela, Gesta, Stephane, Mendez, Armando J, Vishnudas, Vivek K, Sarangarajan, Rangaprasad, Narain, Niven R
Published in Nutrition & metabolism (02.02.2018)
Published in Nutrition & metabolism (02.02.2018)
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Journal Article
Abstract 5542: Identification of Enolase1 as key drug target in breast cancer by the Berg Interrogative Biology™ platform
Jing, Enxuan, Hazarika, Suwagmani, Sundararajan, Pragalath, Fowler, Samantha, Vishnudas, Vivek K., Sarangarajan, Rangaprasad, Narain, Niven R.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism
Suzuki, Ryo, Lee, Kevin, Jing, Enxuan, Biddinger, Sudha B., McDonald, Jeffrey G., Montine, Thomas J., Craft, Suzanne, Kahn, C. Ronald
Published in Cell metabolism (01.12.2010)
Published in Cell metabolism (01.12.2010)
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Journal Article
넌센스 매개 RNA 분해 기반 병태 및 질환 치료를 위한 안티센스 올리고머
LIAU GENE, AZNAREZ ISABEL, JING ENXUAN, TICHO BARUCH, VENKATESH ADITYA, KACH JACOB, SCHARNER JUERGEN
Year of Publication 17.06.2020
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Year of Publication 17.06.2020
Patent
Abstract 1130: API 31510 induced shift in mitochondrial metabolism in cancer cells is characterized by increased mitochondrial efficiency and induction of apoptosis
Jing, Enxuan, Vishnudas, Vivek, Jimnenez, Joaquin J., Narain, Niven R., Sarangarajan, Rangaprasad
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
METHODS OF TREATING A METABOLIC SYNDROME BY MODULATING HEAT SHOCK PROTEIN (HSP) 90-BETA
JING ENXUAN, VISHNUDAS VIVEK K, SARANGARAJAN RANGAPRASAD, NARAIN NIVEN RAJIN
Year of Publication 28.01.2015
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Year of Publication 28.01.2015
Patent