A Randomized, Open‐Label, Controlled Clinical Trial of Azvudine Tablets in the Treatment of Mild and Common COVID‐19, a Pilot Study
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Published in Advanced Science (01.10.2020)
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Integrative Omics Analyses Reveal the Effects of Copper Ions on Salvianolic Acid Biosynthesis
Xiang, Yaping, Wang, Xiaoxiao, Song, Wei, Du, Jinfa, Yin, Xiaojian
Published in Frontiers in plant science (21.10.2021)
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Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
MOSLEY, Ralph T, EDWARDS, Thomas E, MURAKAMI, Eisuke, LAM, Angela M, GRICE, Rena L, JINFA DU, SOFIA, Michael J, FURMAN, Philip A, OTTO, Michael J
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Comparative transcriptome analysis of MeJA-responsive AP2/ERF transcription factors involved in notoginsenosides biosynthesis
Lin, Tingwen, Du, Jinfa, Zheng, Xiaoyan, Zhou, Ping, Li, Ping, Lu, Xu
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An Efficient and Diastereoselective Synthesis of PSI-6130: A Clinically Efficacious Inhibitor of HCV NS5B Polymerase
Wang, Peiyuan, Chun, Byoung-Kwon, Rachakonda, Suguna, Du, Jinfa, Khan, Noshena, Shi, Junxing, Stec, Wojciech, Cleary, Darryl, Ross, Bruce S, Sofia, Michael J
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Published in Journal of organic chemistry (04.09.2009)
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2′-Deoxy-2′-α-fluoro-2′-β- C-methyl 3′,5′-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: Discovery of PSI-352938
Reddy, P. Ganapati, Bao, Donghui, Chang, Wonsuk, Chun, Byoung-Kwon, Du, Jinfa, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Ross, Bruce S., Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine L., Keilman, Meg, Lam, Angela M., Niu, Congrong, Steuer, Holly Micolochick, Furman, Phillip A., Otto, Michael J., Sofia, Michael J.
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
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Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661
Furman, Phillip A., Murakami, Eisuke, Niu, Congrong, Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Bao, Haiying, Tolstykh, Tatiana, Micolochick Steuer, Holly, Keilman, Meg, Zennou, Veronique, Bourne, Nigel, Veselenak, Ronald L., Chang, Wonsuk, Ross, Bruce S., Du, Jinfa, Otto, Michael J., Sofia, Michael J.
Published in Antiviral research (01.08.2011)
Published in Antiviral research (01.08.2011)
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Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine
LAM, Angela M, ESPIRITU, Christine, VESELENAK, Ronald L, GANAPATI REDDY, P, CHANG, Wonsuk, JINFA DU, NAGARATHNAM, Dhanapalan, SOFIA, Michael J, OTTO, Michael J, FURMAN, Phillip A, MURAKAMI, Eisuke, ZENNOU, Veronique, BANSAL, Shalini, MICOLOCHICK STEUER, Holly M, CONGRONG NIU, KEILMAN, Meg, HAIYING BAO, BOURNE, Nigel
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
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Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938
CONGRONG NIU, TOLSTYKH, Tatiana, ZHANG, Hai-Ren, WOOLLY, Joseph, WANG, Li-Quan, CHAO, Piyun B, RAY, Adrian S, OTTO, Michael J, SOFIA, Michael J, FURMAN, Phillip A, MURAKAMI, Eisuke, HAIYING BAO, PARK, Yeojin, BABUSIS, Darius, LAM, Angela M, BANSAL, Shalini, JINFA DU, CHANG, Wonsuk, GANAPATI REDDY, P
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Published in Antimicrobial Agents and Chemotherapy (01.07.2012)
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β-d-2′-α-F-2′-β-C-Methyl-6-O-substituted 3′,5′-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure–activity relationship study
Du, Jinfa, Bao, Donghui, Chun, Byoung-Kwon, Jiang, Ying, Ganapati Reddy, P., Zhang, Hai-Ren, Ross, Bruce S., Bansal, Shalini, Bao, Haiying, Espiritu, Christine, Lam, Angela M., Murakami, Eisuke, Niu, Congrong, Micolochick Steuer, Holly M., Furman, Phillip A., Otto, Michael J., Sofia, Michael J.
Published in Bioorganic & medicinal chemistry letters (15.09.2012)
Published in Bioorganic & medicinal chemistry letters (15.09.2012)
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Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides
Chang, Wonsuk, Du, Jinfa, Rachakonda, Suguna, Ross, Bruce S., Convers-Reignier, Serge, Yau, Wei T., Pons, Jean-Francois, Murakami, Eisuke, Bao, Haiying, Steuer, Holly Micolochick, Furman, Phillip A., Otto, Michael J., Sofia, Michael J.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Synthesis and anti-viral activity of a series of d- and l-2′-deoxy-2′-fluororibonucleosides in the subgenomic HCV replicon system
Shi, Junxing, Du, Jinfa, Ma, Tianwei, Pankiewicz, Krzysztof W., Patterson, Steven E., Tharnish, Phillip M., McBrayer, Tamara R., Stuyver, Lieven J., Otto, Michael J., Chu, Chung K., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Bioorganic & medicinal chemistry (01.03.2005)
Published in Bioorganic & medicinal chemistry (01.03.2005)
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Synthesis and Antiviral Activity of Oxaselenolane Nucleosides
Chu, Chung K, Ma, Li, Olgen, Sureyya, Pierra, Claire, Du, Jinfa, Gumina, Giuseppe, Gullen, Elizabeth, Cheng, Yung-Chi, Schinazi, Raymond F
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Published in Journal of medicinal chemistry (19.10.2000)
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Structure−Activity Relationships of 1-(2-Deoxy-2-fluoro-β-l-arabino- furanosyl)pyrimidine Nucleosides as Anti-Hepatitis B Virus Agents
Ma, Tianwei, Pai, S. Balakrishna, Zhu, Yong Lian, Lin, Ju Sheng, Shanmuganathan, Kirupa, Du, Jinfa, Wang, Chunguang, Kim, Hongbum, Newton, M. Gary, Cheng, Yung Chi, Chu, Chung K
Published in Journal of medicinal chemistry (05.07.1996)
Published in Journal of medicinal chemistry (05.07.1996)
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Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor
Cho, Sunghee, Volpe, Bruce T, Bae, Youngmee, Hwang, Onyou, Choi, Hyun J, Gal, Judit, Park, Larry C. H, Chu, Chung K, Du, Jinfa, Joh, Tong H
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Published in The Journal of neuroscience (01.02.1999)
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Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer
Meng, Yonggang, Yu, Bin, Huang, He, Peng, Youmei, Li, Ertong, Yao, Yongfang, Song, Chuanjun, Yu, Wenquan, Zhu, Kaikai, Wang, Kai, Yi, Dongxu, Du, Jinfa, Chang, Junbiao
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Published in Journal of medicinal chemistry (28.01.2021)
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Mechanism of Action of (-)-(2R,4R)-1-(2-hydroxymethyl-1,3-dioxolan-4-yl)thymine as an anti-HIV agent
Murakami, Eisuke, Bao, Haiying, Basavapathruni, Aravind, Bailey, Christopher M, Du, Jinfa, Steuer, Holly M Micolochick, Niu, Congrong, Whitaker, Tony, Anderson, Karen S, Otto, Michael J, Furman, Phillip A
Published in Antiviral chemistry & chemotherapy (01.04.2007)
Published in Antiviral chemistry & chemotherapy (01.04.2007)
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Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
Sofia, Michael J, Bao, Donghui, Chang, Wonsuk, Du, Jinfa, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Reddy, P. Ganapati, Ross, Bruce S, Wang, Peiyuan, Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine, Keilman, Meg, Lam, Angela M, Steuer, Holly M. Micolochick, Niu, Congrong, Otto, Michael J, Furman, Phillip A
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
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Abstract 3866: Azvudine: An emerging immunomodulator in the treatment of cancer and viral infections
Li, Pan, Jia, Limin, Wang, Zhaoyang, Du, Jinfa
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Synthesis and Biological Activity of 5′,9-Anhydro-3-Purine-ISONucleosides as Potential Anti-Hepatitis C Virus Agents
Chun, Byoung-Kwon, Wang, Peiyuan, Hassan, Abdalla, Du, Jinfa, Tharnish, Phillip M., Murakami, Eisuke, Stuyver, Lieven, Otto, Michael J., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Nucleosides, nucleotides & nucleic acids (01.01.2007)
Published in Nucleosides, nucleotides & nucleic acids (01.01.2007)
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