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Published in The Lancet infectious diseases (01.04.2018)
Published in The Lancet infectious diseases (01.04.2018)
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Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo
Luke, Thomas, Wu, Hua, Zhao, Jincun, Channappanavar, Rudragouda, Coleman, Christopher M, Jiao, Jin-An, Matsushita, Hiroaki, Liu, Ye, Postnikova, Elena N, Ork, Britini L, Glenn, Gregory, Flyer, David, Defang, Gabriel, Raviprakash, Kanakatte, Kochel, Tadeusz, Wang, Jonathan, Nie, Wensheng, Smith, Gale, Hensley, Lisa E, Olinger, Gene G, Kuhn, Jens H, Holbrook, Michael R, Johnson, Reed F, Perlman, Stanley, Sullivan, Eddie, Frieman, Matthew B
Published in Science translational medicine (17.02.2016)
Published in Science translational medicine (17.02.2016)
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Triple immunoglobulin gene knockout transchromosomic cattle: bovine lambda cluster deletion and its effect on fully human polyclonal antibody production
Matsushita, Hiroaki, Sano, Akiko, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J, Wang, Zhongde, Kuroiwa, Yoshimi
Published in PloS one (06.03.2014)
Published in PloS one (06.03.2014)
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Species-Specific Chromosome Engineering Greatly Improves Fully Human Polyclonal Antibody Production Profile in Cattle
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Published in PloS one (24.06.2015)
Published in PloS one (24.06.2015)
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Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattle
Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J, Wang, Zhongde, Kuroiwa, Yoshimi
Published in PloS one (24.10.2013)
Published in PloS one (24.10.2013)
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Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses
Bounds, Callie E, Kwilas, Steven A, Kuehne, Ana I, Brannan, Jennifer M, Bakken, Russell R, Dye, John M, Hooper, Jay W, Dupuy, Lesley C, Ellefsen, Barry, Hannaman, Drew, Wu, Hua, Jiao, Jin-an, Sullivan, Eddie J, Schmaljohn, Connie S
Published in PloS one (30.09.2015)
Published in PloS one (30.09.2015)
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Human polyclonal antibodies produced in transchromosomal cattle prevent lethal Zika virus infection and testicular atrophy in mice
Stein, Derek R., Golden, Joseph W., Griffin, Bryan D., Warner, Bryce M., Ranadheera, Charlene, Scharikow, Leanne, Sloan, Angela, Frost, Kathy L., Kobasa, Darwyn, Booth, Stephanie A., Josleyn, Matthew, Ballantyne, John, Sullivan, Eddie, Jiao, Jin-an, Wu, Hua, Wang, Zhongde, Hooper, Jay W., Safronetz, David
Published in Antiviral research (01.10.2017)
Published in Antiviral research (01.10.2017)
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Correction: Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle
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Published in PloS one (01.01.2014)
Published in PloS one (01.01.2014)
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Bifunctional TGF-β trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors
Liu, Bai, Zhu, Xiaoyun, Kong, Lin, Wang, Meng, Spanoudis, Catherine, Chaturvedi, Pallavi, George, Varghese, Jiao, Jin-an, You, Lijing, Egan, Jack O., Echeverri, Christian, Gallo, Victor L., Xing, Jilan, Ravelo, Kristine, Prendes, Caitlin, Antolinez, Julian, Denissova, Julia, Muniz, Gabriela J., Jeng, Emily K., Rhode, Peter R., Wong, Hing C.
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Published in Molecular therapy (06.10.2021)
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Antibody Preparations from Human Transchromosomic Cows Exhibit Prophylactic and Therapeutic Efficacy against Venezuelan Equine Encephalitis Virus
Gardner, Christina L, Sun, Chengqun, Luke, Thomas, Raviprakash, Kanakatte, Wu, Hua, Jiao, Jin-An, Sullivan, Eddie, Reed, Douglas S, Ryman, Kate D, Klimstra, William B
Published in Journal of virology (15.07.2017)
Published in Journal of virology (15.07.2017)
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Human Polyclonal Antibodies Produced by Transchromosomal Cattle Provide Partial Protection Against Lethal Zaire Ebolavirus Challenge in Rhesus Macaques
Rosenke, Kyle, Bounds, Callie E, Hanley, Patrick W, Saturday, Greg, Sullivan, Eddie, Wu, Hua, Jiao, Jin-An, Feldmann, Heinz, Schmaljohn, Connie, Safronetz, David
Published in The Journal of infectious diseases (22.11.2018)
Published in The Journal of infectious diseases (22.11.2018)
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A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy
Becker-Hapak, Michelle K, Shrestha, Niraj, McClain, Ethan, Dee, Michael J, Chaturvedi, Pallavi, Leclerc, Gilles M, Marsala, Lynne I, Foster, Mark, Schappe, Timothy, Tran, Jennifer, Desai, Sweta, Neal, Carly C, Pence, Patrick, Wong, Pamela, Wagner, Julia A, Russler-Germain, David A, Zhu, Xiaoyun, Spanoudis, Catherine M, Gallo, Victor L, Echeverri, Christian A, Ramirez, Laritza L, You, Lijing, Egan, Jack O, Rhode, Peter R, Jiao, Jin-An, Muniz, Gabriela J, Jeng, Emily K, Prendes, Caitlin A, Sullivan, Ryan P, Berrien-Elliott, Melissa M, Wong, Hing C, Fehniger, Todd A
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DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome
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Published in Science translational medicine (26.11.2014)
Published in Science translational medicine (26.11.2014)
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In Vitro and In Vivo Characterization of a Novel Antibody-Like Single-Chain TCR Human IgG1 Fusion Protein
Mosquera, Luis A, Card, Kimberlyn F, Price-Schiavi, Shari A, Belmont, Heather J, Liu, Bai, Builes, Janette, Zhu, Xiaoyun, Chavaillaz, Pierre-Andre, Lee, Hyung-il, Jiao, Jin-an, Francis, John L, Amirkhosravi, Ali, Wong, Richard L, Wong, Hing C
Published in The Journal of immunology (1950) (01.04.2005)
Published in The Journal of immunology (1950) (01.04.2005)
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Antigen-specific human polyclonal antibodies from hyperimmunized cattle
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Published in Nature biotechnology (01.02.2009)
Published in Nature biotechnology (01.02.2009)
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Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate
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Published in The Journal of Infectious Diseases (22.11.2018)
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Deployment of Transchromosomal Bovine for Personalized Antimicrobial Therapy
Silver, Jared N, Ashbaugh, Cameron D, Miles, Jacob J, Wu, Hua, Marecki, Gregory T, Hwang, Joyce K, Jiao, Jin-An, Abrams, Mark, Sullivan, Eddie J, Wesemann, Duane R
Published in Clinical infectious diseases (19.03.2018)
Published in Clinical infectious diseases (19.03.2018)
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A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity
CARD, Kimberlyn F, PRICE-SCHIAVI, Shari A, SHERMAN, Linda, FRANCIS, John L, AMIRKHOSRAVI, Ali, WONG, Hing C, BAI LIU, THOMSON, Elizabeth, NIEVES, Esperanza, BELMONT, Heather, BUILES, Janette, JIAO, Jin-An, HERNANDEZ, Javier, WEIDANZ, Jon
Published in Cancer Immunology, Immunotherapy (01.04.2004)
Published in Cancer Immunology, Immunotherapy (01.04.2004)
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Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle
Dye, John M., Wu, Hua, Hooper, Jay W., Khurana, Surender, Kuehne, Ana I., Coyle, Elizabeth M., Ortiz, Ramon A., Fuentes, Sandra, Herbert, Andrew S., Golding, Hana, Bakken, Russell A., Brannan, Jennifer M., Kwilas, Steve A., Sullivan, Eddie J., Luke, Thomas C., Smith, Gale, Glenn, Gregory, Li, Wenfang, Ye, Ling, Yang, Chinglai, Compans, Richard W., Tripp, Ralph A., Jiao, Jin-an
Published in Scientific reports (25.04.2016)
Published in Scientific reports (25.04.2016)
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