Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon
Jiang, Wanlong, Wanner, Jutta, Lee, Richard J, Bounaud, Pierre-Yves, Boger, Dale L
Published in Journal of the American Chemical Society (19.02.2003)
Published in Journal of the American Chemical Society (19.02.2003)
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Journal Article
Pyrrolidines as potent functional agonists of the human melanocortin-4 receptor
Tran, Joe A., Chen, Caroline W., Jiang, Wanlong, Tucci, Fabio C., Fleck, Beth A., Marinkovic, Dragan, Arellano, Melissa, Chen, Chen
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Journal Article
Discovery of 1-{2-[(1S)-(3-Dimethylamino-propionyl)amino-2-methylpropyl]-4-methyl-phenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an Orally Active Antagonist of the Melanocortin-4 Receptor for the Potential Treatment of Cachexia
Chen, Chen, Jiang, Wanlong, Tucci, Fabio, Tran, Joe A, Fleck, Beth A, Hoare, Sam R, Joppa, Margaret, Markison, Stacy, Wen, Jenny, Sai, Yang, Johns, Michael, Madan, Ajay, Chen, Takung, Chen, Caroline W, Marinkovic, Dragan, Arellano, Melissa, Saunders, John, Foster, Alan C
Published in Journal of medicinal chemistry (01.11.2007)
Published in Journal of medicinal chemistry (01.11.2007)
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Journal Article
Practical Asymmetric Synthesis of α-Branched 2-Piperazinylbenzylamines by 1,2-Additions of Organometallic Reagents to N-tert-Butanesulfinyl Imines
Jiang, Wanlong, Chen, Chen, Marinkovic, Dragan, Tran, Joe A, Chen, Caroline W, Arellano, L. Melissa, White, Nicole S, Tucci, Fabio C
Published in Journal of organic chemistry (28.10.2005)
Published in Journal of organic chemistry (28.10.2005)
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Journal Article
Syntheses of tetrahydrothiophenes and tetrahydrofurans and studies of their derivatives as melanocortin-4 receptor ligands
Tran, Joe A., Chen, Caroline W., Tucci, Fabio C., Jiang, Wanlong, Fleck, Beth A., Chen, Chen
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Journal Article
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties
Regan, Colin F., Guo, Zhiqiang, Chen, Yongsheng, Huang, Charles Q., Chen, Mi, Jiang, Wanlong, Rueter, Jaimie K., Coon, Timothy, Chen, Chen, Saunders, John, Brown, Michael S., Betz, Steve F., Struthers, R. Scott, Yang, Chun, Wen, Jenny, Madan, Ajay, Zhu, Yun-Fei
Published in Bioorganic & medicinal chemistry (15.08.2008)
Published in Bioorganic & medicinal chemistry (15.08.2008)
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Journal Article
Pharmacological and pharmacokinetic characterization of 2-piperazine-α-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists
Chen, Chen, Tucci, Fabio C., Jiang, Wanlong, Tran, Joe A., Fleck, Beth A., Hoare, Sam R., Wen, Jenny, Chen, Takung, Johns, Michael, Markison, Stacy, Foster, Alan C., Marinkovic, Dragan, Chen, Caroline W., Arellano, Melissa, Harman, John, Saunders, John, Bozigian, Haig, Marks, Daniel
Published in Bioorganic & medicinal chemistry (15.05.2008)
Published in Bioorganic & medicinal chemistry (15.05.2008)
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Journal Article
Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon
Jiang, Wanlong, Wanner, Jutta, Lee, Richard J., Bounaud, Pierre-Yves, Boger, Dale L.
Published in Journal of the American Chemical Society (15.05.2002)
Published in Journal of the American Chemical Society (15.05.2002)
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Journal Article
Identification and characterization of pyrrolidine diastereoisomers as potent functional agonists and antagonists of the human melanocortin-4 receptor
Chen, Chen, Jiang, Wanlong, Tran, Joe A., Tucci, Fabio C., Fleck, Beth A., Markison, Stacy, Wen, Jenny, Madan, Ajay, Hoare, Sam R., Foster, Alan C., Marinkovic, Dragan, Chen, Caroline W., Arellano, Melissa, Saunders, John
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
Synthesis and characterization of trans-4-(4-chlorophenyl)pyrrolidine-3-carboxamides of piperazinecyclohexanes as ligands for the melanocortin-4 receptor
Chen, Caroline W., Tran, Joe A., Fleck, Beth A., Tucci, Fabio C., Jiang, Wanlong, Chen, Chen
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
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Journal Article
Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptor
Jiang, Wanlong, Tucci, Fabio C., Tran, Joe A., Fleck, Beth A., Wen, Jenny, Markison, Stacy, Marinkovic, Dragan, Chen, Caroline W., Arellano, Melissa, Hoare, Sam R., Johns, Michael, Foster, Alan C., Saunders, John, Chen, Chen
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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Journal Article
Synthesis and characterization of pyrrolidine derivatives as potent agonists of the human melanocortin-4 receptor
Jiang, Wanlong, Tran, Joe A., Tucci, Fabio C., Fleck, Beth A., Hoare, Sam R., Markison, Stacy, Wen, Jenny, Chen, Caroline W., Marinkovic, Dragan, Arellano, Melissa, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
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Journal Article
Design, Synthesis, In Vitro, and In Vivo Characterization of Phenylpiperazines and Pyridinylpiperazines as Potent and Selective Antagonists of the Melanocortin-4 Receptor
Tran, Joe A, Jiang, Wanlong, Tucci, Fabio C, Fleck, Beth A, Wen, Jenny, Sai, Yang, Madan, Ajay, Chen, Ta Kung, Markison, Stacy, Foster, Alan C, Hoare, Sam R, Marks, Daniel, Harman, John, Chen, Caroline W, Arellano, Melissa, Marinkovic, Dragan, Bozigian, Haig, Saunders, John, Chen, Chen
Published in Journal of medicinal chemistry (13.12.2007)
Published in Journal of medicinal chemistry (13.12.2007)
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Journal Article
Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor
Jiang, Wanlong, Tucci, Fabio C., Chen, Caroline W., Arellano, Melissa, Tran, Joe A., White, Nicole S., Marinkovic, Dragan, Pontillo, Joseph, Fleck, Beth A., Wen, Jenny, Saunders, John, Madan, Ajay, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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Journal Article
Design and synthesis of 3-arylpyrrolidine-2-carboxamide derivatives as melanocortin-4 receptor ligands
Tran, Joe A., Tucci, Fabio C., Arellano, Melissa, Jiang, Wanlong, Chen, Caroline W., Marinkovic, Dragan, Fleck, Beth A., Wen, Jenny, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activity
Tran, Joe A., Tucci, Fabio C., Jiang, Wanlong, Marinkovic, Dragan, Chen, Caroline W., Arellano, Melissa, Markison, Stacy, Fleck, Beth A., Wen, Jenny, White, Nicole S., Pontillo, Joseph, Saunders, John, Marks, Daniel, Hoare, Sam R., Madan, Ajay, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry (01.08.2007)
Published in Bioorganic & medicinal chemistry (01.08.2007)
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Journal Article
Propionylpiperazines as human melanocortin-4 receptor ligands
Chen, Caroline W., Tran, Joe A., Jiang, Wanlong, Tucci, Fabio C., Arellano, Melissa, Wen, Jenny, Fleck, Beth A., Marinkovic, Dragan, White, Nicole S., Pontillo, Joseph, Saunders, John, Madan, Ajay, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
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Journal Article
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines
Tucci, Fabio C., White, Nicole S., Markison, Stacy, Joppa, Margaret, Tran, Joe A., Fleck, Beth A., Madan, Ajay, Dyck, Brian P., Parker, Jessica, Pontillo, Joseph, Melissa Arellano, L., Marinkovic, Dragan, Jiang, Wanlong, Chen, Caroline W., Gogas, Kathleen R., Goodfellow, Val S., Saunders, John, Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
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Journal Article
Structure–activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptor
Pontillo, Joseph, Tran, Joseph A., Arellano, Melissa, Fleck, Beth A., Huntley, Rajesh, Marinkovic, Dragan, Lanier, Marion, Nelson, Jodie, Parker, Jessica, Saunders, John, Tucci, Fabio C., Jiang, Wanlong, Chen, Caroline W., White, Nicole S., Foster, Alan C., Chen, Chen
Published in Bioorganic & medicinal chemistry letters (06.09.2004)
Published in Bioorganic & medicinal chemistry letters (06.09.2004)
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