Discovery of GS-9256: A novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity
Sheng, X. Christopher, Casarez, Anthony, Cai, Ruby, Clarke, Michael O., Chen, Xiaowu, Cho, Aesop, Delaney, William E., Doerffler, Edward, Ji, Mingzhe, Mertzman, Michael, Pakdaman, Rowchanak, Pyun, Hyung-Jung, Rowe, Tanisha, Wu, Qiaoyin, Xu, Jie, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
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Discovery of GS-9451: An acid inhibitor of the hepatitis C virus NS3/4A protease
Christopher Sheng, X., Appleby, Todd, Butler, Thomas, Cai, Ruby, Chen, Xiaowu, Cho, Aesop, Clarke, Michael O., Cottell, Jeromy, Delaney, William E., Doerffler, Edward, Link, John, Ji, Mingzhe, Pakdaman, Rowchanak, Pyun, Hyung-Jung, Wu, Qiaoyin, Xu, Jie, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
Novel, potent, and orally bioavailable phosphinic acid inhibitors of the hepatitis C virus NS3 protease
Clarke, Michael O., Chen, Xiaowu, Cho, Aesop, Delaney, William E., Doerffler, Edward, Fardis, Maria, Ji, Mingzhe, Mertzman, Michael, Pakdaman, Rowchanak, Pyun, Hyun-Jun, Rowe, Tanisha, Yang, Cheng Y., Sheng, X. Christopher, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Synthesis of 1-amino-2-vinylcyclopropane-1-phosphinates. Conversion of a phosphonate to phosphinates
Pyun, Hyung-Jung, Clarke, Michael O., Cho, Aesop, Casarez, Anthony, Ji, Mingzhe, Fardis, Maria, Pastor, Richard, Sheng, X. Christopher, Kim, Choung U.
Published in Tetrahedron letters (02.05.2012)
Published in Tetrahedron letters (02.05.2012)
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A distal methyl substituent attenuates mitochondrial protein synthesis inhibition in oxazolidinone antibacterials
Renslo, Adam R., Atuegbu, Andy, Herradura, Prudencio, Jaishankar, Priyadarshini, Ji, Mingzhe, Leach, Karen L., Huband, Michael D., Dermyer, Michael R., Wu, Luping, Vara Prasad, J.V.N., Gordeev, Mikhail F.
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle
Mackman, Richard L, Steadman, Victoria A, Dean, David K, Jansa, Petr, Poullennec, Karine G, Appleby, Todd, Austin, Carol, Blakemore, Caroline A, Cai, Ruby, Cannizzaro, Carina, Chin, Gregory, Chiva, Jean-Yves C, Dunbar, Neil A, Fliri, Hans, Highton, Adrian J, Hui, Hon, Ji, Mingzhe, Jin, Haolun, Karki, Kapil, Keats, Andrew J, Lazarides, Linos, Lee, Yu-Jen, Liclican, Albert, Mish, Michael, Murray, Bernard, Pettit, Simon B, Pyun, Peter, Sangi, Michael, Santos, Rex, Sanvoisin, Jonathan, Schmitz, Uli, Schrier, Adam, Siegel, Dustin, Sperandio, David, Stepan, George, Tian, Yang, Watt, Gregory M, Yang, Hai, Schultz, Brian E
Published in Journal of medicinal chemistry (08.11.2018)
Published in Journal of medicinal chemistry (08.11.2018)
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Highly Potent HCV NS4B Inhibitors with Activity against Multiple Genotypes
Phillips, Barton, Cai, Ruby, Delaney, William, Du, Zhimin, Ji, Mingzhe, Jin, Haolun, Lee, Johnny, Li, Jiayao, Niedziela-Majka, Anita, Mish, Michael, Pyun, Hyung-Jung, Saugier, Joe, Tirunagari, Neeraj, Wang, Jianhong, Yang, Huiling, Wu, Qiaoyin, Sheng, Chris, Zonte, Catalin
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
Jin, Haolun, Pyun, Hyung-Jung, Ji, Mingzhe, Trejo Martin, Teresa Alejandra, Desai, Manoj C
Year of Publication 18.07.2024
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Year of Publication 18.07.2024
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Substituted pyrido[1,2-a]pyrrolo[1,2-d]pyrazines for treating viral infections
Jin, Haolun, Pyun, Hyung-Jung, Ji, Mingzhe, Trejo Martin, Teresa Alejandra, Desai, Manoj C
Year of Publication 30.01.2024
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Year of Publication 30.01.2024
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POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
Jin, Haolun, Pyun, Hyung-Jung, Ji, Mingzhe, Trejo Martin, Teresa Alejandra, Desai, Manoj C
Year of Publication 28.07.2022
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Year of Publication 28.07.2022
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Substituted pyrido[1,2-a]pyrrolo[1,2-d]pyrazines for treating viral infections
Jin, Haolun, Pyun, Hyung-Jung, Ji, Mingzhe, Trejo Martin, Teresa Alejandra, Desai, Manoj C
Year of Publication 04.01.2022
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Year of Publication 04.01.2022
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Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections
Martin, Teresa Alejandra Trejo, Pyun, Hyung-Jung, Jin, Haolun, Ji, Mingzhe, Desai, Manoj C
Year of Publication 26.03.2021
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Year of Publication 26.03.2021
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