Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
Liu, David, Schilling, Bastian, Liu, Derek, Sucker, Antje, Livingstone, Elisabeth, Jerby-Arnon, Livnat, Zimmer, Lisa, Gutzmer, Ralf, Satzger, Imke, Loquai, Carmen, Grabbe, Stephan, Vokes, Natalie, Margolis, Claire A., Conway, Jake, He, Meng Xiao, Elmarakeby, Haitham, Dietlein, Felix, Miao, Diana, Tracy, Adam, Gogas, Helen, Goldinger, Simone M., Utikal, Jochen, Blank, Christian U., Rauschenberg, Ricarda, von Bubnoff, Dagmar, Krackhardt, Angela, Weide, Benjamin, Haferkamp, Sebastian, Kiecker, Felix, Izar, Ben, Garraway, Levi, Regev, Aviv, Flaherty, Keith, Paschen, Annette, Van Allen, Eliezer M., Schadendorf, Dirk
Published in Nature medicine (01.12.2019)
Published in Nature medicine (01.12.2019)
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Journal Article
Predicting selective drug targets in cancer through metabolic networks
Folger, Ori, Jerby, Livnat, Frezza, Christian, Gottlieb, Eyal, Ruppin, Eytan, Shlomi, Tomer
Published in Molecular systems biology (21.06.2011)
Published in Molecular systems biology (21.06.2011)
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Journal Article
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
Zheng, Liang, Cardaci, Simone, Jerby, Livnat, MacKenzie, Elaine D., Sciacovelli, Marco, Johnson, T. Isaac, Gaude, Edoardo, King, Ayala, Leach, Joshua D. G., Edrada-Ebel, RuAngelie, Hedley, Ann, Morrice, Nicholas A., Kalna, Gabriela, Blyth, Karen, Ruppin, Eytan, Frezza, Christian, Gottlieb, Eyal
Published in Nature communications (23.01.2015)
Published in Nature communications (23.01.2015)
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Journal Article
Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease
Hyötyläinen, Tuulia, Jerby, Livnat, Petäjä, Elina M., Mattila, Ismo, Jäntti, Sirkku, Auvinen, Petri, Gastaldelli, Amalia, Yki-Järvinen, Hannele, Ruppin, Eytan, Orešič, Matej
Published in Nature communications (03.02.2016)
Published in Nature communications (03.02.2016)
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Journal Article
Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
JERBY, Livnat, WOLF, Lior, DENKERT, Carsten, STEIN, Gideon Y, HILVO, Mika, ORESIC, Matej, GEIGER, Tamar, RUPPIN, Eytan
Published in Cancer research (Chicago, Ill.) (15.11.2012)
Published in Cancer research (Chicago, Ill.) (15.11.2012)
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Journal Article
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Slyper, Michal, Porter, Caroline B. M., Ashenberg, Orr, Waldman, Julia, Drokhlyansky, Eugene, Wakiro, Isaac, Smillie, Christopher, Smith-Rosario, Gabriela, Wu, Jingyi, Dionne, Danielle, Vigneau, Sébastien, Jané-Valbuena, Judit, Tickle, Timothy L., Napolitano, Sara, Su, Mei-Ju, Patel, Anand G., Karlstrom, Asa, Gritsch, Simon, Nomura, Masashi, Waghray, Avinash, Gohil, Satyen H., Tsankov, Alexander M., Jerby-Arnon, Livnat, Cohen, Ofir, Klughammer, Johanna, Rosen, Yanay, Gould, Joshua, Nguyen, Lan, Hofree, Matan, Tramontozzi, Peter J., Li, Bo, Wu, Catherine J., Izar, Benjamin, Haq, Rizwan, Hodi, F. Stephen, Yoon, Charles H., Hata, Aaron N., Baker, Suzanne J., Suvà, Mario L., Bueno, Raphael, Stover, Elizabeth H., Clay, Michael R., Dyer, Michael A., Collins, Natalie B., Matulonis, Ursula A., Wagle, Nikhil, Johnson, Bruce E., Rotem, Asaf, Rozenblatt-Rosen, Orit, Regev, Aviv
Published in Nature medicine (01.05.2020)
Published in Nature medicine (01.05.2020)
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Journal Article
A single-cell landscape of high-grade serous ovarian cancer
Izar, Benjamin, Tirosh, Itay, Stover, Elizabeth H., Wakiro, Isaac, Cuoco, Michael S., Alter, Idan, Rodman, Christopher, Leeson, Rachel, Su, Mei-Ju, Shah, Parin, Iwanicki, Marcin, Walker, Sarah R., Kanodia, Abhay, Melms, Johannes C., Mei, Shaolin, Lin, Jia-Ren, Porter, Caroline B. M., Slyper, Michal, Waldman, Julia, Jerby-Arnon, Livnat, Ashenberg, Orr, Brinker, Titus J., Mills, Caitlin, Rogava, Meri, Vigneau, Sébastien, Sorger, Peter K., Garraway, Levi A., Konstantinopoulos, Panagiotis A., Liu, Joyce F., Matulonis, Ursula, Johnson, Bruce E., Rozenblatt-Rosen, Orit, Rotem, Asaf, Regev, Aviv
Published in Nature medicine (01.08.2020)
Published in Nature medicine (01.08.2020)
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Journal Article
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
Sahu, Avinash Das, S Lee, Joo, Wang, Zhiyong, Zhang, Gao, Iglesias‐Bartolome, Ramiro, Tian, Tian, Wei, Zhi, Miao, Benchun, Nair, Nishanth Ulhas, Ponomarova, Olga, Friedman, Adam A, Amzallag, Arnaud, Moll, Tabea, Kasumova, Gyulnara, Greninger, Patricia, Egan, Regina K, Damon, Leah J, Frederick, Dennie T, Jerby‐Arnon, Livnat, Wagner, Allon, Cheng, Kuoyuan, Park, Seung Gu, Robinson, Welles, Gardner, Kevin, Boland, Genevieve, Hannenhalli, Sridhar, Herlyn, Meenhard, Benes, Cyril, Flaherty, Keith, Luo, Ji, Gutkind, J Silvio, Ruppin, Eytan
Published in Molecular systems biology (01.03.2019)
Published in Molecular systems biology (01.03.2019)
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Journal Article
Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality
Jerby-Arnon, Livnat, Pfetzer, Nadja, Waldman, Yedael Y., McGarry, Lynn, James, Daniel, Shanks, Emma, Seashore-Ludlow, Brinton, Weinstock, Adam, Geiger, Tamar, Clemons, Paul A., Gottlieb, Eyal, Ruppin, Eytan
Published in Cell (28.08.2014)
Published in Cell (28.08.2014)
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Journal Article
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Jerby-Arnon, Livnat, Neftel, Cyril, Shore, Marni E., Weisman, Hannah R., Mathewson, Nathan D., McBride, Matthew J., Haas, Brian, Izar, Benjamin, Volorio, Angela, Boulay, Gaylor, Cironi, Luisa, Richman, Alyssa R., Broye, Liliane C., Gurski, Joseph M., Luo, Christina C., Mylvaganam, Ravindra, Nguyen, Lan, Mei, Shaolin, Melms, Johannes C., Georgescu, Christophe, Cohen, Ofir, Buendia-Buendia, Jorge E., Segerstolpe, Asa, Sud, Malika, Cuoco, Michael S., Labes, Danny, Gritsch, Simon, Zollinger, Daniel R., Ortogero, Nicole, Beechem, Joseph M., Petur Nielsen, G., Chebib, Ivan, Nguyen-Ngoc, Tu, Montemurro, Michael, Cote, Gregory M., Choy, Edwin, Letovanec, Igor, Cherix, Stéphane, Wagle, Nikhil, Sorger, Peter K., Haynes, Alex B., Mullen, John T., Stamenkovic, Ivan, Rivera, Miguel N., Kadoch, Cigall, Wucherpfennig, Kai W., Rozenblatt-Rosen, Orit, Suvà, Mario L., Riggi, Nicolò, Regev, Aviv
Published in Nature medicine (01.02.2021)
Published in Nature medicine (01.02.2021)
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Journal Article
Harnessing synthetic lethality to predict the response to cancer treatment
Lee, Joo Sang, Das, Avinash, Jerby-Arnon, Livnat, Arafeh, Rand, Auslander, Noam, Davidson, Matthew, McGarry, Lynn, James, Daniel, Amzallag, Arnaud, Park, Seung Gu, Cheng, Kuoyuan, Robinson, Welles, Atias, Dikla, Stossel, Chani, Buzhor, Ella, Stein, Gidi, Waterfall, Joshua J., Meltzer, Paul S., Golan, Talia, Hannenhalli, Sridhar, Gottlieb, Eyal, Benes, Cyril H., Samuels, Yardena, Shanks, Emma, Ruppin, Eytan
Published in Nature communications (29.06.2018)
Published in Nature communications (29.06.2018)
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Journal Article
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Barnabas, Georgina D, Lee, Joo Sang, Shami, Tamar, Harel, Michal, Beck, Lir, Selitrennik, Michael, Jerby-Arnon, Livnat, Erez, Neta, Ruppin, Eytan, Geiger, Tamar
Published in Cancer research (Chicago, Ill.) (15.03.2021)
Published in Cancer research (Chicago, Ill.) (15.03.2021)
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Journal Article
IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development
Li, Amy, Herbst, Rebecca H., Canner, David, Schenkel, Jason M., Smith, Olivia C., Kim, Jonathan Y., Hillman, Michelle, Bhutkar, Arjun, Cuoco, Michael S., Rappazzo, C. Garrett, Rogers, Patricia, Dang, Celeste, Jerby-Arnon, Livnat, Rozenblatt-Rosen, Orit, Cong, Le, Birnbaum, Michael, Regev, Aviv, Jacks, Tyler
Published in Cell reports (Cambridge) (03.12.2019)
Published in Cell reports (Cambridge) (03.12.2019)
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Journal Article
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
Dixit, Atray, Parnas, Oren, Li, Biyu, Chen, Jenny, Fulco, Charles P., Jerby-Arnon, Livnat, Marjanovic, Nemanja D., Dionne, Danielle, Burks, Tyler, Raychowdhury, Raktima, Adamson, Britt, Norman, Thomas M., Lander, Eric S., Weissman, Jonathan S., Friedman, Nir, Regev, Aviv
Published in Cell (15.12.2016)
Published in Cell (15.12.2016)
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Journal Article
Author Correction: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Slyper, Michal, Porter, Caroline B. M., Ashenberg, Orr, Waldman, Julia, Drokhlyansky, Eugene, Wakiro, Isaac, Smillie, Christopher, Smith-Rosario, Gabriela, Wu, Jingyi, Dionne, Danielle, Vigneau, Sébastien, Jané-Valbuena, Judit, Tickle, Timothy L., Napolitano, Sara, Su, Mei-Ju, Patel, Anand G., Karlstrom, Asa, Gritsch, Simon, Nomura, Masashi, Waghray, Avinash, Gohil, Satyen H., Tsankov, Alexander M., Jerby-Arnon, Livnat, Cohen, Ofir, Klughammer, Johanna, Rosen, Yanay, Gould, Joshua, Nguyen, Lan, Hofree, Matan, Tramontozzi, Peter J., Li, Bo, Wu, Catherine J., Izar, Benjamin, Haq, Rizwan, Hodi, F. Stephen, Yoon, Charles H., Hata, Aaron N., Baker, Suzanne J., Suvà, Mario L., Bueno, Raphael, Stover, Elizabeth H., Clay, Michael R., Dyer, Michael A., Collins, Natalie B., Matulonis, Ursula A., Wagle, Nikhil, Johnson, Bruce E., Rotem, Asaf, Rozenblatt-Rosen, Orit, Regev, Aviv
Published in Nature medicine (01.08.2020)
Published in Nature medicine (01.08.2020)
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Journal Article
Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
Liu, David, Schilling, Bastian, Liu, Derek, Sucker, Antje, Livingstone, Elisabeth, Jerby-Arnon, Livnat, Zimmer, Lisa, Gutzmer, Ralf, Satzger, Imke, Loquai, Carmen, Grabbe, Stephan, Vokes, Natalie, Margolis, Claire A., Conway, Jake, He, Meng Xiao, Elmarakeby, Haitham, Dietlein, Felix, Miao, Diana, Tracy, Adam, Gogas, Helen, Goldinger, Simone M., Utikal, Jochen, Blank, Christian U., Rauschenberg, Ricarda, von Bubnoff, Dagmar, Krackhardt, Angela, Weide, Benjamin, Haferkamp, Sebastian, Kiecker, Felix, Izar, Ben, Garraway, Levi, Regev, Aviv, Flaherty, Keith, Paschen, Annette, Van Allen, Eliezer M., Schadendorf, Dirk
Published in Nature medicine (01.07.2020)
Published in Nature medicine (01.07.2020)
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Journal Article
Spatial transcriptomics
Anderson, Ana C., Yanai, Itai, Yates, Lucy R., Wang, Linghua, Swarbrick, Alexander, Sorger, Peter, Santagata, Sandro, Fridman, Wolf H., Gao, Qiang, Jerby, Livnat, Izar, Benjamin, Shang, Lulu, Zhou, Xiang
Published in Cancer cell (12.09.2022)
Published in Cancer cell (12.09.2022)
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Journal Article
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
Frezza, Christian, Zheng, Liang, Folger, Ori, Rajagopalan, Kartik N., MacKenzie, Elaine D., Jerby, Livnat, Micaroni, Massimo, Chaneton, Barbara, Adam, Julie, Hedley, Ann, Kalna, Gabriela, Tomlinson, Ian P. M., Pollard, Patrick J., Watson, Dave G., Deberardinis, Ralph J., Shlomi, Tomer, Ruppin, Eytan, Gottlieb, Eyal
Published in Nature (London) (08.09.2011)
Published in Nature (London) (08.09.2011)
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