Glycointeractions in bacterial pathogenesis
Poole, Jessica, Day, Christopher J., von Itzstein, Mark, Paton, James C., Jennings, Michael P.
Published in Nature reviews. Microbiology (01.07.2018)
Published in Nature reviews. Microbiology (01.07.2018)
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Journal Article
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
Coll, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B., Schroder, Kate
Published in Nature chemical biology (01.06.2019)
Published in Nature chemical biology (01.06.2019)
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Journal Article
Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1
DuMont, Ashley L., Yoong, Pauline, Day, Christopher J., Alonzo, Francis, McDonald, W. Hayes, Jennings, Michael P., Torres, Victor J.
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions
Day, Christopher J, Bailly, Benjamin, Guillon, Patrice, Dirr, Larissa, Jen, Freda E-C, Spillings, Belinda L, Mak, Johnson, von Itzstein, Mark, Haselhorst, Thomas, Jennings, Michael P
Published in mBio (30.03.2021)
Published in mBio (30.03.2021)
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Journal Article
A random six-phase switch regulates pneumococcal virulence via global epigenetic changes
Manso, Ana Sousa, Chai, Melissa H., Atack, John M., Furi, Leonardo, De Ste Croix, Megan, Haigh, Richard, Trappetti, Claudia, Ogunniyi, Abiodun D., Shewell, Lucy K., Boitano, Matthew, Clark, Tyson A., Korlach, Jonas, Blades, Matthew, Mirkes, Evgeny, Gorban, Alexander N., Paton, James C., Jennings, Michael P., Oggioni, Marco R.
Published in Nature communications (30.09.2014)
Published in Nature communications (30.09.2014)
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Journal Article
Glycan: glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells
Day, Christopher J., Tran, Elizabeth N., Semchenko, Evgeny A., Tram, Greg, Hartley-Tassell, Lauren E., Ng, Preston S. K., King, Rebecca M., Ulanovsky, Rachel, McAtamney, Sarah, Apicella, Michael A., Tiralongo, Joe, Morona, Renato, Korolik, Victoria, Jennings, Michael P.
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2015)
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Journal Article
N-glycolylneuraminic acid as a carbohydrate cancer biomarker
Wang, Jing, Shewell, Lucy K., Day, Christopher J., Jennings, Michael P.
Published in Translational oncology (01.05.2023)
Published in Translational oncology (01.05.2023)
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Journal Article
The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells
Apicella, Michael A, Edwards, Jennifer L, Ketterer, Margaret R, Weiss, David S, Zhang, Yuan, Jen, Freda E-C, Jennings, Michael P
Published in mBio (16.10.2024)
Published in mBio (16.10.2024)
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Effect of GPR84 deletion on obesity and diabetes development in mice fed long chain or medium chain fatty acid rich diets
Du Toit, Eugene, Browne, Liam, Irving-Rodgers, Helen, Massa, Helen M., Fozzard, Nicolette, Jennings, Michael P., Peak, Ian R.
Published in European journal of nutrition (01.08.2018)
Published in European journal of nutrition (01.08.2018)
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Journal Article
cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity
Shewell, Lucy K, Harvey, Richard M, Higgins, Melanie A, Day, Christopher J, Hartley-Tassell, Lauren E, Chen, Austen Y, Gillen, Christine M, James, David B A, Alonzo, 3rd, Francis, Torres, Victor J, Walker, Mark J, Paton, Adrienne W, Paton, James C, Jennings, Michael P
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
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Journal Article
Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes
Spaan, András N., Reyes-Robles, Tamara, Badiou, Cédric, Cochet, Sylvie, Boguslawski, Kristina M., Yoong, Pauline, Day, Christopher J., de Haas, Carla J.C., van Kessel, Kok P.M., Vandenesch, François, Jennings, Michael P., Le Van Kim, Caroline, Colin, Yves, van Strijp, Jos A.G., Henry, Thomas, Torres, Victor J.
Published in Cell host & microbe (09.09.2015)
Published in Cell host & microbe (09.09.2015)
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Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors
Ng, Preston S.K., Böhm, Raphael, Hartley-Tassell, Lauren E., Steen, Jason A., Wang, Hui, Lukowski, Samuel W., Hawthorne, Paula L., Trezise, Ann E.O., Coloe, Peter J., Grimmond, Sean M., Haselhorst, Thomas, von Itzstein, Mark, Paton, Adrienne W., Paton, James C., Jennings, Michael P.
Published in Nature communications (17.12.2014)
Published in Nature communications (17.12.2014)
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Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions
Nahar, Nusrat, Tram, Greg, Jen, Freda E-C, Phillips, Zachary N, Weinert, Lucy A, Bossé, Janine T, Jabbari, Jafar S, Gouil, Quentin, Du, Mei R M, Ritchie, Matthew E, Bowden, Rory, Langford, Paul R, Tucker, Alexander W, Jennings, Michael P, Turni, Conny, Blackall, Patrick J, Atack, John M
Published in Nucleic acids research (24.04.2023)
Published in Nucleic acids research (24.04.2023)
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N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease
Shewell, Lucy K, Day, Christopher J, Kutasovic, Jamie R, Abrahams, Jodie L, Wang, Jing, Poole, Jessica, Niland, Colleen, Ferguson, Kaltin, Saunus, Jodi M, Lakhani, Sunil R, von Itzstein, Mark, Paton, James C, Paton, Adrienne W, Jennings, Michael P
Published in BMC cancer (26.03.2022)
Published in BMC cancer (26.03.2022)
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Journal Article
Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells
Poole, Jessica, Day, Christopher J, Haselhorst, Thomas, Jen, Freda E-C, Torres, Victor J, Edwards, Jennifer L, Jennings, Michael P
Published in mBio (03.03.2020)
Published in mBio (03.03.2020)
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Journal Article
Analysis of Bacterial Phosphorylcholine-Related Genes Reveals an Association between Type-Specific Biosynthesis Pathways and Biomolecules Targeted for Phosphorylcholine Modification
Zhang, Yuan, Jen, Freda E-C, Edwards, Jennifer L, Jennings, Michael P
Published in Microbiology spectrum (17.08.2023)
Published in Microbiology spectrum (17.08.2023)
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