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Suofu, Yalikun, Li, Wei, Jean-Alphonse, Frédéric G., Jia, Jiaoying, Khattar, Nicolas K., Li, Jiatong, Baranov, Sergei V., Leronni, Daniela, Mihalik, Amanda C., He, Yanqing, Cecon, Erika, Wehbi, Vanessa L., Kim, JinHo, Heath, Brianna E., Baranova, Oxana V., Wang, Xiaomin, Gable, Matthew J., Kretz, Eric S., Di Benedetto, Giulietta, Lezon, Timothy R., Ferrando, Lisa M., Larkin, Timothy M., Sullivan, Mara, Yablonska, Svitlana, Wang, Jingjing, Minnigh, M. Beth, Guillaumet, Gérald, Suzenet, Franck, Richardson, R. Mark, Poloyac, Samuel M., Stolz, Donna B., Jockers, Ralf, Witt-Enderby, Paula A., Carlisle, Diane L., Vilardaga, Jean-Pierre, Friedlander, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (19.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (19.09.2017)
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Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation
White, Alex D, Peña, Karina A, Clark, Lisa J, Maria, Christian Santa, Liu, Shi, Jean-Alphonse, Frédéric G, Lee, Ji Young, Lei, Saifei, Cheng, Zhiqiang, Tu, Chia-Ling, Fang, Fei, Szeto, Nicholas, Gardella, Thomas J, Xiao, Kunhong, Gellman, Samuel H, Bahar, Ivet, Sutkeviciute, Ieva, Chang, Wenhan, Vilardaga, Jean-Pierre
Published in Science signaling (05.10.2021)
Published in Science signaling (05.10.2021)
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A single‐domain intrabody targeting the follicle‐stimulating hormone receptor impacts FSH‐induced G protein‐dependent signalling
Raynaud, Pauline, Jugnarain, Vinesh, Vaugrente, Océane, Vallet, Amandine, Boulo, Thomas, Gauthier, Camille, Inoue, Asuka, Sibille, Nathalie, Gauthier, Christophe, Jean‐Alphonse, Frédéric, Reiter, Eric, Crépieux, Pascale, Bruneau, Gilles
Published in FEBS letters (01.01.2024)
Published in FEBS letters (01.01.2024)
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Ca2+ allostery in PTH-receptor signaling
White, Alex D., Fang, Fei, Jean-Alphonse, Frédéric G., Clark, Lisa J., An, Hyun-Jung, Liu, Hongda, Zhao, Yang, Reynolds, Shelley L., Lee, Sihoon, Xiao, Kunhong, Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
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Biased GPCR signaling by the native parathyroid hormone–related protein 1 to 141 relative to its N-terminal fragment 1 to 36
Peña, Karina A., White, Alex D., Savransky, Sofya, Castillo, Ignacio Portales, Jean-Alphonse, Frédéric G., Gardella, Thomas J., Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Published in The Journal of biological chemistry (01.09.2022)
Published in The Journal of biological chemistry (01.09.2022)
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Design and validation of the first cell‐impermeant melatonin receptor agonist
Gbahou, Florence, Cecon, Erika, Viault, Guillaume, Gerbier, Romain, Jean‐Alphonse, Frederic, Karamitri, Angeliki, Guillaumet, Gérald, Delagrange, Philippe, Friedlander, Robert M, Vilardaga, Jean‐Pierre, Suzenet, Franck, Jockers, Ralf
Published in British journal of pharmacology (01.07.2017)
Published in British journal of pharmacology (01.07.2017)
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Intracellular VHHs to monitor and modulate GPCR signaling
Raynaud, Pauline, Gauthier, Camille, Jugnarain, Vinesh, Jean-Alphonse, Frédéric, Reiter, Eric, Bruneau, Gilles, Crépieux, Pascale
Published in Frontiers in endocrinology (Lausanne) (16.11.2022)
Published in Frontiers in endocrinology (Lausanne) (16.11.2022)
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Ca 2+ allostery in PTH-receptor signaling
White, Alex D, Fang, Fei, Jean-Alphonse, Frédéric G, Clark, Lisa J, An, Hyun-Jung, Liu, Hongda, Zhao, Yang, Reynolds, Shelley L, Lee, Sihoon, Xiao, Kunhong, Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2019)
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Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells
Bhattacharyya, Sohinee, Jean‐Alphonse, Frédéric G., Raghavan, Venkatesan, McGarvey, Jennifer C., Rbaibi, Youssef, Vilardaga, Jean‐Pierre, Carattino, Marcelo D., Weisz, Ora A.
Published in Physiological reports (01.10.2017)
Published in Physiological reports (01.10.2017)
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Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential[S]
Nikolopoulou, Evanthia, Papacleovoulou, Georgia, Jean-Alphonse, Frederic, Grimaldi, Giulia, Parker, Malcolm G., Hanyaloglu, Aylin C., Christian, Mark
Published in Journal of lipid research (01.12.2014)
Published in Journal of lipid research (01.12.2014)
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Endosomal generation of cAMP in GPCR signaling
Vilardaga, Jean-Pierre, Jean-Alphonse, Frederic G, Gardella, Thomas J
Published in Nature chemical biology (01.09.2014)
Published in Nature chemical biology (01.09.2014)
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Spatially Restricted G Protein-coupled Receptor Activity via Divergent Endocytic Compartments
Jean-Alphonse, Frederic, Bowersox, Shanna, Chen, Stanford, Beard, Gemma, Puthenveedu, Manojkumar A., Hanyaloglu, Aylin C.
Published in The Journal of biological chemistry (14.02.2014)
Published in The Journal of biological chemistry (14.02.2014)
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Structure and dynamics of the active human parathyroid hormone receptor-1
Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X Edward, de Waal, Parker W, Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J, Jean-Alphonse, Frederic G, White, Alex D, Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J, Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H Eric, Zhang, Yan
Published in Science (American Association for the Advancement of Science) (12.04.2019)
Published in Science (American Association for the Advancement of Science) (12.04.2019)
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An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis
Gauthier, Camille, Raynaud, Pauline, Jean-Alphonse, Frédéric, Vallet, Amandine, Vaugrente, Océane, Jugnarain, Vinesh, Boulo, Thomas, Gauthier, Christophe, Reiter, Eric, Bruneau, Gilles, Crépieux, Pascale
Published in Molecular and cellular endocrinology (01.08.2024)
Published in Molecular and cellular endocrinology (01.08.2024)
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Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport
Zhang, Qiangmin, Xiao, Kunhong, Paredes, José M., Mamonova, Tatyana, Sneddon, W. Bruce, Liu, Hongda, Wang, Dawei, Li, Sheng, McGarvey, Jennifer C., Uehling, David, Al-awar, Rima, Joseph, Babu, Jean-Alphonse, Frederic, Orte, Angel, Friedman, Peter A.
Published in The Journal of biological chemistry (22.03.2019)
Published in The Journal of biological chemistry (22.03.2019)
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Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
Clark, Lisa J., Krieger, James, White, Alex D., Bondarenko, Vasyl, Lei, Saifei, Fang, Fei, Lee, Ji Young, Doruker, Pemra, Böttke, Thore, Jean-Alphonse, Frederic, Tang, Pei, Gardella, Thomas J., Xiao, Kunhong, Sutkeviciute, Ieva, Coin, Irene, Bahar, Ivet, Vilardaga, Jean-Pierre
Published in Nature chemical biology (01.10.2020)
Published in Nature chemical biology (01.10.2020)
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Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor‑1 Signaling via Biased Agonism
Liu, Shi, Jean-Alphonse, Frederic G, White, Alex D, Wootten, Denise, Sexton, Patrick M, Gardella, Thomas J, Vilardaga, Jean-Pierre, Gellman, Samuel H
Published in Journal of the American Chemical Society (18.09.2019)
Published in Journal of the American Chemical Society (18.09.2019)
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Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase
Gidon, Alexandre, Al-Bataineh, Mohammad M, Jean-Alphonse, Frederic G, Stevenson, Hilary P, Watanabe, Tomoyuki, Louet, Claire, Khatri, Ashok, Calero, Guillermo, Pastor-Soler, Núria M, Gardella, Thomas J, Vilardaga, Jean-Pierre
Published in Nature chemical biology (01.09.2014)
Published in Nature chemical biology (01.09.2014)
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The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking
Xu, Yaoxian, Streets, Andrew J, Hounslow, Andrea M, Tran, Uyen, Jean-Alphonse, Frederic, Needham, Andrew J, Vilardaga, Jean-Pierre, Wessely, Oliver, Williamson, Michael P, Ong, Albert C M
Published in Journal of the American Society of Nephrology (01.04.2016)
Published in Journal of the American Society of Nephrology (01.04.2016)
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Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling
McGarvey, Jennifer C., Xiao, Kunhong, Bowman, Shanna L., Mamonova, Tatyana, Zhang, Qiangmin, Bisello, Alessandro, Sneddon, W. Bruce, Ardura, Juan A., Jean-Alphonse, Frederic, Vilardaga, Jean-Pierre, Puthenveedu, Manojkumar A., Friedman, Peter A.
Published in The Journal of biological chemistry (20.05.2016)
Published in The Journal of biological chemistry (20.05.2016)
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