Long-enduring primary hepatocyte-based co-cultures improve prediction of hepatotoxicity
Novik, Eric I., Dwyer, Jacquelyn, Morelli, James K., Parekh, Amit, Cho, Cheul, Pludwinski, Eitan, Shrirao, Anil, Freedman, Robert M., MacDonald, James S., Jayyosi, Zaid
Published in Toxicology and applied pharmacology (01.12.2017)
Published in Toxicology and applied pharmacology (01.12.2017)
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Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor
He, Wei, Myers, Michael R., Hanney, Barbara, Spada, Alfred P., Bilder, Glenda, Galzcinski, Helen, Amin, Dilip, Needle, Saul, Page, Ken, Jayyosi, Zaid, Perrone, Mark H.
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
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The Simultaneous Inhibition of Solute Carrier Family 6 Member 19 and Breast Cancer Resistance Protein Transporters Leads to an Increase of Indoxyl Sulfate (a Uremic Toxin) in Plasma and Kidney
Wang, Qingping, Munteanu, Bogdan, Marker, Alexander, Luo, Yongyi, Holz, Constanze, Kane, John L., Kuntzweiler, Theresa, Poulton, Emma-Jane, Sedic, Maja, Jayyosi, Zaid, Riedel, Jens, Fretland, Jennifer
Published in Drug metabolism and disposition (01.11.2024)
Published in Drug metabolism and disposition (01.11.2024)
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Journal Article
Regulation of Two Members of the Steroid-Inducible Cytochrome P450 Subfamily (3A) in Rats
Cooper, K.O., Reik, L.M., Jayyosi, Z., Bandiera, S., Kelley, M., Ryan, D.E., Daniel, R., Mccluskey, S.A., Levin, W., Thomas, P.E.
Published in Archives of biochemistry and biophysics (01.03.1993)
Published in Archives of biochemistry and biophysics (01.03.1993)
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The simultaneous inhibition of SLC6A19 and BCRP transporters leads to an increase of indoxyl sulfate (a uremic toxin) in plasma and kidney
Wang, Qingping, Munteanu, Bogdan, Marker, Alexander, Luo, Yongyi, Holz, Constanze, Kane, Jr, John L, Kuntzweiler, Theresa, Poulton, Emma-Jane, Sedic, Maja, Jayyosi, Zaid, Riedel, Jens, Fretland, Jennifer
Published in Drug metabolism and disposition (09.09.2024)
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Published in Drug metabolism and disposition (09.09.2024)
Journal Article
Induction of heat shock protein 70 by herbimycin A and cyclopentenone prostaglandins in smooth muscle cells
Hamel, Linda, Kenney, Margaret, Jayyosi, Zaid, Ardati, Ali, Clark, Ken, Spada, Al, Zilberstein, Asher, Perrone, Mark, Kaplow, June, Merkel, Linda, Rojas, Camilo
Published in Cell stress & chaperones (01.04.2000)
Published in Cell stress & chaperones (01.04.2000)
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Toxicologic and carcinogenic effects of the type IV phosphodiesterase inhibitor RP 73401 on the nasal olfactory tissue in rats
Pino, M V, Valerio, M G, Miller, G K, Larson, J L, Rosolia, D L, Jayyosi, Z, Crouch, C N, Trojanowski, J Q, Geiger, L E
Published in Toxicologic pathology (01.07.1999)
Published in Toxicologic pathology (01.07.1999)
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Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine
Singhal, Rohit, Harrill, Alison H, Menguy-Vacheron, Francoise, Jayyosi, Zaid, Benzerdjeb, Hadj, Watkins, Paul B
Published in BMC pharmacology & toxicology (03.08.2014)
Published in BMC pharmacology & toxicology (03.08.2014)
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Journal Article
The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy
MCLAY, Lain M, HALLEY, Frank, FOSTER, Martyn, HELE, David, JAYYOSI, Zaid, KELLEY, Mike, MASLEN, Chris, MILLER, Glen, OULDELHKIM, Marie-Claude, PAGE, Kenneth, PHIPPS, Simon, POLLOCK, Kenneth, SOUNESS, John E, PORTER, Barry, RATCLIFFE, Andrew J, REDFORD, Elisabeth J, WEBBER, Stephen, SLATER, Bryan, THYBAUD, Veronique, WILSHER, Nicola, MCKENNA, Jeffrey, BENNING, Veronique, BIRRELL, Mark, BURTON, Brenda, BELVISI, Maria, COLLIS, Alan, CONSTAN, Alex
Published in Bioorganic & medicinal chemistry (01.02.2001)
Published in Bioorganic & medicinal chemistry (01.02.2001)
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Journal Article
The hepatic transcriptome as a window on whole-body physiology and pathophysiology
Morgan, Kevin T, Jayyosi, Zaid, Hower, Moira A, Pino, Michael V, Connolly, Timothy M, Kotlenga, Katja, Lin, Jieyi, Wang, Min, Schmidts, Hans-Ludwig, Bonnefoi, Marc S, Elston, Timothy C, Boorman, Gary A
Published in Toxicologic pathology (2005)
Published in Toxicologic pathology (2005)
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Complementary roles for toxicologic pathology and mathematics in toxicogenomics, with special reference to data interpretation and oscillatory dynamics
Morgan, Kevin T, Pino, Michael, Crosby, Lynn M, Wang, Min, Elston, Timothy C, Jayyosi, Zaid, Bonnefoi, Marc, Boorman, Gary
Published in Toxicologic pathology (01.03.2004)
Published in Toxicologic pathology (01.03.2004)
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Journal Article
Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525
BONNEFOI, M. S, KELLEY, M. F, WELLS, R. E, SANDERS, J. E, ZAID JAYYOSI, BEYS, E, KORNBRUST, D. J, LANGLOSS, J. M
Published in Fundamental and applied toxicology (01.11.1995)
Published in Fundamental and applied toxicology (01.11.1995)
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Journal Article
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: The synthesis and biological activities of RPR127963 an orally bioavailable inhibitor: Recent advances in the design of kinase inhibitors as novel therapeutic agents
WEI HE, MYERS, Michael R, PERRONE, Mark H, HANNEY, Barbara, SPADA, Alfred P, BILDER, Glenda, GALZCINSKI, Helen, AMIN, Dilip, NEEDLE, Saul, PAGE, Ken, JAYYOSI, Zaid
Published in Bioorganic & medicinal chemistry letters (2003)
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Published in Bioorganic & medicinal chemistry letters (2003)
Journal Article
Brain cytochrome P450 and testosterone metabolism by rat brain subcellular fractions: Presence of cytochrome P450 3A immunoreactive protein in rat brain mitochondria
Jayyosi, Zaid, Cooper, Kathryn O., Thomas, Paul E.
Published in Archives of biochemistry and biophysics (01.10.1992)
Published in Archives of biochemistry and biophysics (01.10.1992)
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Quantitation of N-(3,5-dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide and 4-amino-3,5-dichloropyridine in rat and mouse plasma by LC/MS/MS
Cassidy, Kenneth C, Muc, Margaret, Hsu, Roger, Jayyosi, Zaid, Marietta, Michael P
Published in Journal of pharmaceutical and biomedical analysis (01.06.2000)
Published in Journal of pharmaceutical and biomedical analysis (01.06.2000)
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Journal Article
Subchronic Toxicity Studies with the Leukotriene D4 Antagonist RG 12525
BONNEFOI, MARC S., KELLEY, MICHAEL F., WELLS, ROGER E., SANDERS, JAMES E., JAYYOSI, ZAID, BEYS, ERIC, KORNBRUST, DOUGLAS J., LANGLOSS, ZAID
Published in Toxicological sciences (01.11.1995)
Published in Toxicological sciences (01.11.1995)
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