Abstract P3-10-10: PMD-026, a first-in-class oral p90 ribosomal S6 kinase (RSK) inhibitor for triple negative breast cancer (TNBC)
Dunn, Sandra E., Jayanthan, Aarthi, Huynh, My-my, Flahive, Erik, Pambid, Mary Rose, Dorr, Andrew, Los, Gerrit
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Get full text
Journal Article
Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion
Kosnopfel, Corinna, Wendlinger, Simone, Niessner, Heike, Siewert, Johannes, Sinnberg, Tobias, Hofmann, Angelika, Wohlfarth, Jonas, Schrama, David, Berthold, Marion, Siedel, Claudia, Sauer, Birgit, Jayanthan, Aarthi, Lenz, Georg, Dunn, Sandra E, Schilling, Bastian, Schittek, Birgit
Published in Journal of experimental & clinical cancer research (19.07.2023)
Published in Journal of experimental & clinical cancer research (19.07.2023)
Get full text
Journal Article
Abstract PS11-33: A first-in-human Phase 1/1b multicenter, open-label dose escalation study to assess safety and tolerability of PMD-026, a first-in-class oral RSK inhibitor, in metastatic breast cancer patients
Beeram, Murali, Wang, Judy S., Chalasani, Pavani, Mina, Lida, Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Los, Gerrit, Dunn, Sandra E., Dorr, F. Andrew
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Get full text
Journal Article
In Vitro Sensitivity Profiling of Neuroblastoma Cells Against A Comprehensive Small Molecule Kinase Inhibitor Library to Identify Agents for Future Therapeutic Studies
Singh, Anjali, Meier-Stephenson, Vanessa, Jayanthan, Aarthi, Narendran, Aru
Published in Current cancer drug targets (01.01.2017)
Published in Current cancer drug targets (01.01.2017)
Get more information
Journal Article
Double-deleted vaccinia virus in virotherapy for refractory and metastatic pediatric solid tumors
Lun, Xueqing, Ruan, Yibing, Jayanthan, Aarthi, Liu, David J., Singh, Anjali, Trippett, Tanya, Bell, John, Forsyth, Peter, Johnston, Randal N., Narendran, Aru
Published in Molecular oncology (01.10.2013)
Published in Molecular oncology (01.10.2013)
Get full text
Journal Article
Establishment of atypical-teratoid/rhabdoid tumor (AT/RT) cell cultures from disseminated CSF cells: a model to elucidate biology and potential targeted therapeutics
Narendran, Aru, Coppes, Lucas, Jayanthan, Aarthi, Coppes, Michael, Teja, Bijan, Bernoux, Delphine, George, David, Strother, Douglas
Published in Journal of neuro-oncology (01.11.2008)
Published in Journal of neuro-oncology (01.11.2008)
Get full text
Journal Article
Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on pediatric acute lymphoblastic leukemia (ALL) with respect to Bcr-Abl status and imatinib mesylate sensitivity
HAWKINS, Lindsay M, JAYANTHAN, Aarthi A, NARENDRAN, Aru
Published in Pediatric research (01.03.2005)
Published in Pediatric research (01.03.2005)
Get full text
Journal Article
Establishment of a t(11;19), KMT2A Rearranged B-ALL Cell Line for Preclinical Evaluation and Novel Therapeutics Development for Refractory Infant Leukemia
Sharma, Ritul, Incoronato, Andrea, Zhang, Chunfen, Jayanthan, Aarthi, Shah, Ravi, Narendran, Aru
Published in Journal of pediatric hematology/oncology (01.08.2023)
Published in Journal of pediatric hematology/oncology (01.08.2023)
Get more information
Journal Article
Human SNF5 arming of double-deleted vaccinia virus shows oncolytic and cytostatic activity against central nervous system atypical teratoid/rhabdoid tumor cells
Thakur, Satbir, Ruan, Yibing, Zhang, Chunfen, Lun, Xueqing, Jayanthan, Aarthi, Narendran, Aru
Published in Cancer gene therapy (01.08.2021)
Published in Cancer gene therapy (01.08.2021)
Get full text
Journal Article
Abstract 1038: PMD-026, a first in class oral RSK inhibitor, demonstrates synergy when combined with standard of care in breast cancer tumor models
Jayanthan, Aarthi, Huynh, My-my, Lee, Jangsoon, Los, Gerrit, Yue, Lambert, Pambid, Mary Rose, Ueno, Naoto T., Dunn, Sandra E.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 1218: Targeting B-RAF and checkpoint inhibitor resistant melanoma with RSK inhibitor PMD-026 in pre-clinical models
Ramos, Joe William, Si, Stephanie, Fujii, Takeo, Haun, Brien, Yang, Won Seok, Jayanthan, Aarthi, Dunn, Sandra E.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients
MIETTUNEN, Paivi M, NARENDRAN, Aru, JAYANTHAN, Aarthi, BEHRENS, Edward M, CRON, Randy Q
Published in Rheumatology (Oxford, England) (01.02.2011)
Published in Rheumatology (Oxford, England) (01.02.2011)
Get full text
Journal Article
The dawn of targeted therapies for triple negative breast cancer (TNBC): a snapshot of investigational drugs in phase I and II trials
Huynh, My-My, Pambid, Mary Rose, Jayanthan, Aarthi, Dorr, Andrew, Los, Gerrit, Dunn, Sandra E
Published in Expert opinion on investigational drugs (01.11.2020)
Published in Expert opinion on investigational drugs (01.11.2020)
Get more information
Journal Article
The T-type Calcium Channel Cav3.1 in Y79 Retinoblastoma Cells is Regulated by the Epidermal Growth Factor Receptor via the MAPK Signaling Pathway
Banderali, Umberto, Jain, Mohit, Thakur, Satbir, Jayanthan, Aarthi, Belke, Darrell D., Giles, Wayne R., Narendran, Aru
Published in Current eye research (04.03.2022)
Published in Current eye research (04.03.2022)
Get full text
Journal Article
First-in-human phase I/Ib multicenter, open-label dose escalation study to assess safety and tolerability of PMD-026 in patients with metastatic breast cancer with expansion in metastatic triple negative breast cancer
Beeram, Muralidhar, Wang, Judy Sing-Zan, Mina, Lida A., Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Dunn, Sandra Elaine, Los, Gerrit, Dorr, Andrew
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
Get full text
Journal Article
First-in-human phase 1/1b expansion of PMD-026, an oral RSK inhibitor, in patients with metastatic triple-negative breast cancer
Beeram, Muralidhar, Chalasani, Pavani, Wang, Judy S., Mina, Lida A., Shatsky, Rebecca Arielle, Trivedi, Meghna S., Wesolowski, Robert, Hurvitz, Sara A., Han, Hyo S., Patnaik, Amita, Pambid, Mary Rose, Jayanthan, Aarthi, Huynh, My-my, Los, Gerrit, Dunn, Sandra Elaine, Dorr, Andrew
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Abstract P5-17-12: First-in-human expansion study of oral PMD-026 in metastatic triple negative breast cancer patients
Beeram, Muralidhar, Wang, Judy S., Mina, Lida A., Chalasani, Pavani, Shatsky, Rebecca A., Wesolowski, Robert, Hurvitz, Sara A., Trivedi, Meghna S., Han, Hyo S., Patnaik, Amita, Huynh, My-my, Jayanthan, Aarthi, Pambid, Mary Rose, Yue, Lambert, Los, Gerrit, Dunn, Sandra E., Dorr, Andrew
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Get full text
Journal Article