Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms
Barraud, Nicolas, Buson, Alberto, Jarolimek, Wolfgang, Rice, Scott A
Published in PloS one (13.12.2013)
Published in PloS one (13.12.2013)
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Journal Article
Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse
Nguyen, Long T., Saad, Sonia, Shi, Ying, Wang, Rosy, Chou, Angela S. Y., Gill, Anthony, Yao, Yimin, Jarolimek, Wolfgang, Pollock, Carol A.
Published in Scientific reports (14.06.2021)
Published in Scientific reports (14.06.2021)
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Journal Article
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis
Jones, Mark G, Andriotis, Orestis G, Roberts, James Jw, Lunn, Kerry, Tear, Victoria J, Cao, Lucy, Ask, Kjetil, Smart, David E, Bonfanti, Alessandra, Johnson, Peter, Alzetani, Aiman, Conforti, Franco, Doherty, Regan, Lai, Chester Y, Johnson, Benjamin, Bourdakos, Konstantinos N, Fletcher, Sophie V, Marshall, Ben G, Jogai, Sanjay, Brereton, Christopher J, Chee, Serena J, Ottensmeier, Christian H, Sime, Patricia, Gauldie, Jack, Kolb, Martin, Mahajan, Sumeet, Fabre, Aurelie, Bhaskar, Atul, Jarolimek, Wolfgang, Richeldi, Luca, O'Reilly, Katherine Ma, Monk, Phillip D, Thurner, Philipp J, Davies, Donna E
Published in eLife (03.07.2018)
Published in eLife (03.07.2018)
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Journal Article
Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis
Yao, Yimin, Findlay, Alison, Stolp, Jessica, Rayner, Benjamin, Ask, Kjetil, Jarolimek, Wolfgang
Published in International journal of molecular sciences (16.05.2022)
Published in International journal of molecular sciences (16.05.2022)
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Journal Article
Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice
Leiva, Orly, Ng, Seng Kah, Matsuura, Shinobu, Chitalia, Vipul, Lucero, Hector, Findlay, Alison, Turner, Craig, Jarolimek, Wolfgang, Ravid, Katya
Published in International journal of hematology (01.12.2019)
Published in International journal of hematology (01.12.2019)
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Journal Article
Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis
Chaudhari, Nutan, Findlay, Alison D., Stevenson, Andrew W., Clemons, Tristan D., Yao, Yimin, Joshi, Amar, Sayyar, Sepidar, Wallace, Gordon, Rea, Suzanne, Toshniwal, Priyanka, Deng, Zhenjun, Melton, Philip E., Hortin, Nicole, Iyer, K. Swaminathan, Jarolimek, Wolfgang, Wood, Fiona M., Fear, Mark W.
Published in Nature communications (22.09.2022)
Published in Nature communications (22.09.2022)
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Journal Article
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
Chang, Joan, Lucas, Morghan C, Leonte, Lidia E, Garcia-Montolio, Marc, Singh, Lukram Babloo, Findlay, Alison D, Deodhar, Mandar, Foot, Jonathan S, Jarolimek, Wolfgang, Timpson, Paul, Erler, Janine T, Cox, Thomas R
Published in Oncotarget (18.04.2017)
Published in Oncotarget (18.04.2017)
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Journal Article
Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy
Wong, May YW, Saad, Sonia, Wong, Muh Geot, Stangenberg, Stefanie, Jarolimek, Wolfgang, Schilter, Heidi, Zaky, Amgad, Gill, Anthony, Pollock, Carol, Joles, Jaap A
Published in PloS one (18.06.2020)
Published in PloS one (18.06.2020)
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Journal Article
Author Correction: Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis
Chaudhari, Nutan, Findlay, Alison D., Stevenson, Andrew W., Clemons, Tristan D., Yao, Yimin, Joshi, Amar, Sayyar, Sepidar, Wallace, Gordon, Rea, Suzanne, Toshniwal, Priyanka, Deng, Zhenjun, Melton, Philip E., Hortin, Nicole, Iyer, K. Swaminathan, Jarolimek, Wolfgang, Wood, Fiona M., Fear, Mark W.
Published in Nature communications (10.01.2023)
Published in Nature communications (10.01.2023)
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Journal Article
Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration
Schilter, Heidi C, Collison, Adam, Russo, Remo C, Foot, Jonathan S, Yow, Tin T, Vieira, Angelica T, Tavares, Livia D, Mattes, Joerg, Teixeira, Mauro M, Jarolimek, Wolfgang
Published in Respiratory research (20.03.2015)
Published in Respiratory research (20.03.2015)
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Journal Article
A Novel MAO-B/SSAO Inhibitor Improves Multiple Aspects of Dystrophic Phenotype in mdx Mice
Gasparella, Francesca, Nogara, Leonardo, Germinario, Elena, Tibaudo, Lucia, Ciciliot, Stefano, Piccoli, Giorgia, Venegas, Francisca Carolina, Fontana, Francesca, Sales, Gabriele, Sabbatini, Daniele, Foot, Jonathan, Jarolimek, Wolfgang, Blaauw, Bert, Canton, Marcella, Vitiello, Libero
Published in Antioxidants (21.05.2024)
Published in Antioxidants (21.05.2024)
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Journal Article
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
Findlay, Alison, Turner, Craig, Schilter, Heidi, Deodhar, Mandar, Zhou, Wenbin, Perryman, Lara, Foot, Jonathan, Zahoor, Amna, Yao, Yimin, Hamilton, Ross, Brock, Mary, Raso, Christina, Stolp, Jessica, Galati, Marie, Hamprecht, Dieter, Charlton, Brett, Jarolimek, Wolfgang
Published in Clinical and translational medicine (01.11.2021)
Published in Clinical and translational medicine (01.11.2021)
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Journal Article
Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model
Wong, May, Saad, Sonia, Zhang, Jie, Gross, Simon, Jarolimek, Wolfgang, Schilter, Heidi, Chen, Jason A, Gill, Anthony J, Pollock, Carol A, Wong, Muh Geot
Published in American journal of physiology. Renal physiology (15.10.2014)
Published in American journal of physiology. Renal physiology (15.10.2014)
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Journal Article
The effect of non-specific tight junction modulators on the transepithelial transport of poorly permeable drugs across airway epithelial cells
Ghadiri, Maliheh, Young, Paul M., Jarolimek, Wolfgang, Grau, Georges E. R., Oliver, Brian G. G., Traini, Daniela
Published in Journal of drug targeting (21.04.2017)
Published in Journal of drug targeting (21.04.2017)
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Journal Article
Molecular Determinants of Dofetilide Block of HERG K+ Channels
Ficker, Eckhard, Jarolimek, Wolfgang, Kiehn, Johann, Baumann, Arnd, Brown, Arthur M
Published in Circulation research (23.02.1998)
Published in Circulation research (23.02.1998)
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Journal Article
Functional Properties of the High-Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist (4-Hydroxy-5-iodo-3-methoxyphenylacetate ester) Iodo-Resiniferatoxin
Seabrook, Guy R, Sutton, Kathy G, Jarolimek, Wolfgang, Hollingworth, Gregory J, Teague, Simon, Webb, Janine, Clark, Natalie, Boyce, Susan, Kerby, Julie, Ali, Zahid, Chou, Margaret, Middleton, Richard, Kaczorowski, Gregory, Jones, A Brian
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
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Journal Article
Rational design of an in vitro safety profiling panel to reduce undesired secondary pharmacology of drug candidates
Whitebread, Steven, Bowes, Joanne, Brown, Andrew, Hamon, Jacques, Jarolimek, Wolfgang G., Waldron, Gareth, Sridhar, Arun
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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