A Comparison of the Pharmacokinetics and Pharmacodynamics of Pregabalin and Gabapentin
Bockbrader, Howard N., Wesche, David, Miller, Raymond, Chapel, Sunny, Janiczek, Nancy, Burger, Paula
Published in Clinical pharmacokinetics (01.10.2010)
Published in Clinical pharmacokinetics (01.10.2010)
Get full text
Journal Article
Rational Design, Synthesis, and Biological Activity of Benzoxazinones as Novel Factor Xa Inhibitors
Dudley, Danette A, Bunker, Amy M, Chi, Liguo, Cody, Wayne L, Holland, Debra R, Ignasiak, Diane P, Janiczek-Dolphin, Nancy, McClanahan, Thomas B, Mertz, Thomas E, Narasimhan, Lakshmi S, Rapundalo, Stephen T, Trautschold, Julia A, Van Huis, Chad A, Edmunds, Jeremy J
Published in Journal of medicinal chemistry (02.11.2000)
Published in Journal of medicinal chemistry (02.11.2000)
Get full text
Journal Article
The antithrombotic effects of CI-1031 (ZK-807834) and enoxaparin in a canine electrolytic injury model of arterial and venous thrombosis
McClanahan, Thomas B, Hicks, Gary W, Morrison, Angela L, Peng, Yun-Wen, Janiczek-Dolphin, Nancy, Mertz, Thomas E, Sullivan, Mark E, Morser, John, Juneau, Paul L, Leadley, Robert
Published in European journal of pharmacology (07.12.2001)
Published in European journal of pharmacology (07.12.2001)
Get full text
Journal Article
The Discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an Orally Efficacious Factor Xa Inhibitor
Kohrt, Jeffrey T., Bigge, Christopher F., Bryant, John W., Casimiro-Garcia, Agustin, Chi, Liguo, Cody, Wayne L., Dahring, Tawny, Dudley, Danette A., Filipski, Kevin J., Haarer, Staci, Heemstra, Ron, Janiczek, Nancy, Narasimhan, Lakshmi, McClanahan, Thomas, Peterson, J. Thomas, Sahasrabudhe, Vaisheli, Schaum, Robert, Van Huis, Chad A., Welch, Kathleen M., Zhang, Erli, Leadley, Robert J., Edmunds, Jeremy J.
Published in Chemical biology & drug design (01.08.2007)
Published in Chemical biology & drug design (01.08.2007)
Get full text
Journal Article
The discovery of glycine and related amino acid-based factor Xa inhibitors
Kohrt, Jeffrey T., Filipski, Kevin J., Cody, Wayne L., Bigge, Christopher F., La, Frances, Welch, Kathleen, Dahring, Tawny, Bryant, John W., Leonard, Daniele, Bolton, Gary, Narasimhan, Lakshmi, Zhang, Erli, Peterson, J. Thomas, Haarer, Staci, Sahasrabudhe, Vaishali, Janiczek, Nancy, Desiraju, Shrilakshmi, Hena, Mostofa, Fiakpui, Charles, Saraswat, Neerja, Sharma, Raman, Sun, Shaoyi, Maiti, Samarendra N., Leadley, Robert, Edmunds, Jeremy J.
Published in Bioorganic & medicinal chemistry (01.07.2006)
Published in Bioorganic & medicinal chemistry (01.07.2006)
Get full text
Journal Article
Structure-based Drug Design of Pyrrolidine-1, 2-dicarboxamides as a Novel Series of Orally Bioavailable Factor Xa Inhibitors
Van Huis, Chad A., Bigge, Christopher F., Casimiro-Garcia, Agustin, Cody, Wayne L., Dudley, Danette A., Filipski, Kevin J., Heemstra, Ronald J., Kohrt, Jeffrey T., Narasimhan, Lakshmi S., Schaum, Robert P., Zhang, Erli, Bryant, John W., Haarer, Staci, Janiczek, Nancy, Leadley Jr, Robert J., McClanahan, Thomas, Thomas Peterson, J., Welch, Kathleen M., Edmunds, Jeremy J.
Published in Chemical biology & drug design (01.06.2007)
Published in Chemical biology & drug design (01.06.2007)
Get full text
Journal Article
Formulation modifications of PD 0313052, a direct Factor Xa Inhibitor, alter pharmacokinetics and pharma-codynamics following subcutaneous administration to rabbits
Peng, Yun-Wen, Chi, Liguo, Gibson, Glenn, Janiczek, Nancy, Juneau, Paul, Ross, Daniel, A Perrin, Lisa, Leadley, Robert
Published in Journal of pharmacy & pharmaceutical sciences (2006)
Get full text
Published in Journal of pharmacy & pharmaceutical sciences (2006)
Journal Article
In vitro and in vivo antithrombotic activity of PD-198961, a novel synthetic factor Xa inhibitor
Chi, Liguo, Peng, Yun-Wen, Gibson, Glenn, Hicks, Gary, Mertz, Thomas E, Rapundalo, Stephen, Janiczek, Nancy, Edmunds, Jeremy J, Leadley, Robert
Published in Journal of cardiovascular pharmacology (01.10.2004)
Published in Journal of cardiovascular pharmacology (01.10.2004)
Get more information
Journal Article
The Discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolid ine-1,2-dicarboxamide (PD 0348292), an Orally Efficacious Factor Xa Inhibitor
Kohrt, Jeffrey T, Bigge, Christopher F, Bryant, John W, Casimiro-Garcia, Agustin, Chi, Liguo, Cody, Wayne L, Dahring, Tawny, Dudley, Danette A, Filipski, Kevin J, Haarer, Staci, Heemstra, Ron, Janiczek, Nancy, Narasimhan, Lakshmi, McClanahan, Thomas, Peterson, JThomas, Sahasrabudhe, Vaisheli, Schaum, Robert, Van Huis, Chad A, Welch, Kathleen M, Zhang, Erli, Leadley, Robert J, Edmunds, Jeremy J
Published in Chemical biology & drug design (01.08.2007)
Published in Chemical biology & drug design (01.08.2007)
Get full text
Journal Article
Assessment of ex vivo Pharmacodynamic Markers during Inhibition of Thrombosis by CI-1031 (ZK-807834), a Novel Direct Factor Xa Inhibitor
Chi, Liguo, Pen, Yun-Wen, Potoczak, Ronald, Gibson, Glenn, Hicks, Gary, Mertz, Thomas E., Janiczek, Nancy, Juneau, Paul L., Gallagher, Kim, Leadley, Robert
Published in Pharmacology (01.02.2002)
Published in Pharmacology (01.02.2002)
Get full text
Journal Article
Antithrombotic effect of LB-30057 (CI-1028), a new synthetic thrombin inhibitor, in a rabbit model of thrombosis: Comparison with inogatran
LIGUO CHI, MERTZ, Thomas E, ROGERS, Karen L, JANICZEK, Nancy, PENG, Yun-Wen, SAGANEK, Lori, BOUSLEY, Richard F, JUNEAU, Paul L, UPRICHARD, Andrew C. G, GALLAGHER, Kim P
Published in Journal of thrombosis and thrombolysis (01.02.2001)
Published in Journal of thrombosis and thrombolysis (01.02.2001)
Get full text
Journal Article
Tandem-in-Time Mass Spectrometry as a Quantitative Bioanalytical Tool
Rossi, David T, Hoffman, Keith L, Janiczek-Dolphin, Nancy, Bockbrader, Howard, Parker, Tresavon D
Published in Analytical chemistry (Washington) (15.11.1997)
Published in Analytical chemistry (Washington) (15.11.1997)
Get full text
Journal Article
The antithrombotic effects of CI-1028, an orally bioavailable direct thrombin inhibitor, in a canine model of venous and arterial thrombosis
MCCLANAHAN, Thomas B, HICKS, Gary W, IGNASIAK, Diane P, BOUSLEY, Richard, MERTZ, Thomas E, JUNEAU, Paul, JANICZEK-DOLPHIN, Nancy, KIM, In-Chull, GALLAGHER, Kim P
Published in Journal of thrombosis and thrombolysis (01.12.2000)
Published in Journal of thrombosis and thrombolysis (01.12.2000)
Get full text
Journal Article