The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models
Zhang, Sen, Anjum, Rana, Squillace, Rachel, Nadworny, Sara, Zhou, Tianjun, Keats, Jeff, Ning, Yaoyu, Wardwell, Scott D, Miller, David, Song, Youngchul, Eichinger, Lindsey, Moran, Lauren, Huang, Wei-Sheng, Liu, Shuangying, Zou, Dong, Wang, Yihan, Mohemmad, Qurish, Jang, Hyun Gyung, Ye, Emily, Narasimhan, Narayana, Wang, Frank, Miret, Juan, Zhu, Xiaotian, Clackson, Tim, Dalgarno, David, Shakespeare, William C, Rivera, Victor M
Published in Clinical cancer research (15.11.2016)
Published in Clinical cancer research (15.11.2016)
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Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
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Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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Recurrent SETBP1 mutations in atypical chronic myeloid leukemia
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Published in Nature genetics (01.01.2013)
Published in Nature genetics (01.01.2013)
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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Published in Nature (London) (10.12.2009)
Published in Nature (London) (10.12.2009)
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Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models
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Published in Nature communications (08.02.2021)
Published in Nature communications (08.02.2021)
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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Published in Nature (London) (17.06.2010)
Published in Nature (London) (17.06.2010)
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Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
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Published in The Journal of experimental medicine (15.02.2010)
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METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS
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Year of Publication 09.02.2017
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Year of Publication 09.02.2017
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METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS
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Year of Publication 12.03.2015
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Year of Publication 12.03.2015
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TCT-652 Coronary Artery Calcium Score in Predicting Periprocedural Myocardial Infarction in Patients Undergoing Elective Percutaneous Coronary Intervention
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2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)
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Published in Bioanalysis (01.11.2018)
Published in Bioanalysis (01.11.2018)
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O4‐05‐02: THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE‐3972‐01 PREFERENTIALLY REDUCES G4C2 REPEAT‐CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA
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Published in Alzheimer's & dementia (01.07.2018)
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O4‐05‐02: THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE‐3972‐01 PREFERENTIALLY REDUCES G 4 C 2 REPEAT‐CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA
Dodart, Jean-Cosme, Liu, Yuanjing, Tran, Helene, Berkovitch, Shaunna, Byrne, Michael, Durbin, Ann, Iwamoto, Naoki, Jang, Hyun Gyung, Kandasamy, Pachamuthu, Liu, Fangjun, Mohapatra, Susovan, Yang, Hailin, Yin, Yuan, Zhang, Jason, Zhong, Zhong, Vargeese, Chandra, Brown, Robert H.
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE-3972-01 PREFERENTIALLY REDUCES G4C2 REPEAT-CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA
Dodart, Jean-Cosme, Liu, Yuanjing, Tran, Helene, Berkovitch, Shaunna, Byrne, Michael, Durbin, Ann, Iwamoto, Naoki, Jang, Hyun Gyung, Kandasamy, Pachamuthu, Liu, Fangjun, Mohapatra, Susovan, Yang, Hailin, Yin, Yuan, Zhang, Jason, Zhong, Zhong, Vargeese, Chandra, Brown, Robert H.
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Published in World journal of clinical cases (26.01.2021)
Published in World journal of clinical cases (26.01.2021)
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Coronary artery calcium score in predicting periprocedural myocardial infarction in patients undergoing an elective percutaneous coronary intervention
Kang, Min Gyu, Kang, Yoomee, Jang, Hyun Gyung, Kim, Kyehwan, Koh, Jin-Sin, Park, Jeong Rang, Hwang, Seok-Jae, Hwang, Jin-Yong, Bae, Jae Seok, Ahn, Jong-Hwa, Jang, Jeong Yoon, Park, Yongwhi, Jeong, Young-Hoon, Kwak, Choong Hwan, Park, Hyun Woong
Published in Coronary artery disease (01.11.2018)
Published in Coronary artery disease (01.11.2018)
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2018 White Paper on Recent Issues in Bioanalysis
Welink, Jan, Xu, Yuanxin, Yang, Eric, Wilson, Amanda, Henderson, Neil, Luo, Lina, Fraser, Stephanie, Kavita, Uma, Musuku, Adrien, James, Christopher, Fraier, Daniela, Zhang, Yan, Goykhman, Dina, Summerfield, Scott, Woolf, Eric, Verhaeghe, Tom, Hughes, Nicola, Behling, Alexander, Brown, Kirk, Bulychev, Alex, Buonarati, Michael, Cherry, Elana, Cho, Seongeun (Julia), Cludts, Isabelle, Dillen, Lieve, Dodge, Robert, Edmison, Anna, Garofolo, Fabio, Green, Rachel, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jang, Hyun Gyung, Ji, Allena, Jones, Barry, Kassim, Sean, Ma, Mark, Lima Santos, Gustavo Mendes, Norris, Daniel A, Owen, Tate, Piccoli, Steven, Ramanathan, Ragu, Röhl, Ingo, Rosenbaum, Anton I, Saito, Yoshiro, Sangster, Timothy, Savoie, Natasha, Stebbins, Christopher, Sydor, Jens, de Merbel, Nico van, Verthelyi, Daniela, Vinter, Stephen, Whale, Emma
Published in Bioanalysis (01.11.2018)
Published in Bioanalysis (01.11.2018)
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Abstract 3176: Recurrent SETBP1 mutations in atypical chronic myeloid leukemia abrogate an ubiquitination site and dysregulate SETBP1 protein levels
Piazza, Rocco, Valletta, Simona, Winkelmann, Nils, Redaelli, Sara, Spinelli, Roberta, Pirola, Alessandra, Antolini, Laura, Mologni, Luca, Donadoni, Carla, Papaemmanuil, Elli, Schnittger, Susanne, Dong-Wook, Kim, Boultwood, Jacqueline, Rossi, Fabio, Gaipa, Giuseppe, De Martini, Greta, di Celle, Paola Francia, Jang, Hyun Gyung, Fantin, Valeria, Bignell, Graham R., Magistroni, Vera, Haferlach, Torsten, Pogliani, Enrico Maria, Campbell, Peter, Chase, Andrew J., Tapper, William J., Cross, Nick C.P., Gambacorti Passerini, Carlo
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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