Search Results - "JAMES C POWERS" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis

Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis

by Gloeckl, Sarina, Ong, Vanissa A., Patel, Pooja, Tyndall, Joel D. A., Timms, Peter, Beagley, Kenneth W., Allan, John A., Armitage, Charles W., Turnbull, Lynne, Whitchurch, Cynthia B., Merdanovic, Melisa, Ehrmann, Michael, Powers, James C., Oleksyszyn, Jozef, Verdoes, Martijn, Bogyo, Matthew, Huston, Wilhelmina M.
Published in Molecular microbiology (01.08.2013)

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Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide

Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide

by Lee, Ting-Wai, Cherney, Maia M., Huitema, Carly, Liu, Jie, James, Karen Ellis, Powers, James C., Eltis, Lindsay D., James, Michael N.G.
Published in Journal of molecular biology (11.11.2005)

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Substrate specificity of transthyretin: identification of natural substrates in the nervous system

Substrate specificity of transthyretin: identification of natural substrates in the nervous system

by Liz, Márcia A, Fleming, Carolina E, Nunes, Ana F, Almeida, Maria R, Mar, Fernando M, Choe, Youngchool, Craik, Charles S, Powers, James C, Bogyo, Matthew, Sousa, Mónica M
Published in Biochemical journal (15.04.2009)

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Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase

Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase

by Lee, Ting-Wai, Cherney, Maia M., Liu, Jie, James, Karen Ellis, Powers, James C., Eltis, Lindsay D., James, Michael N.G.
Published in Journal of molecular biology (23.02.2007)

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Aza-Peptide Michael Acceptors: A New Class of Inhibitors Specific for Caspases and Other Clan CD Cysteine Proteases

Aza-Peptide Michael Acceptors: A New Class of Inhibitors Specific for Caspases and Other Clan CD Cysteine Proteases

by Ekici, Özlem Doǧan, Götz, Marion G., James, Karen Ellis, Li, Zhao Zhao, Rukamp, Brian J., Asgian, Juliana L., Caffrey, Conor R., Hansell, Elizabeth, Dvořák, Jan, McKerrow, James H., Potempa, Jan, Travis, James, Mikolajczyk, Jowita, Salvesen, Guy S., Powers, James C.
Published in Journal of medicinal chemistry (08.04.2004)

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Design, Synthesis, and Evaluation of Aza-Peptide Epoxides as Selective and Potent Inhibitors of Caspases-1, -3, -6, and -8

Design, Synthesis, and Evaluation of Aza-Peptide Epoxides as Selective and Potent Inhibitors of Caspases-1, -3, -6, and -8

by James, Karen Ellis, Asgian, Juliana L, Li, Zhao Zhao, Ekici, Özlem Doǧan, Rubin, John R, Mikolajczyk, Jowita, Salvesen, Guy S, Powers, James C
Published in Journal of medicinal chemistry (11.03.2004)

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Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

by Bogyo, Matthew, Arastu-Kapur, Shirin, Ponder, Elizabeth L, Fonovi, Urša Pe ar, Yeoh, Sharon, Yuan, Fang, Fonovi, Marko, Grainger, Munira, Phillips, Carolyn I, Powers, James C
Published in Nature chemical biology (01.03.2008)

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Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases

Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases

by Powers, James C, Asgian, Juliana L, Ekici, Özlem Doǧan, James, Karen Ellis
Published in Chemical reviews (01.12.2002)

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Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion

Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion

by Child, Matthew A, Hall, Carolyn I, Beck, Josh R, Ofori, Leslie O, Albrow, Victoria E, Garland, Megan, Bowyer, Paul W, Bradley, Peter J, Powers, James C, Boothroyd, John C, Weerapana, Eranthie, Bogyo, Matthew
Published in Nature chemical biology (01.10.2013)

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Inhibition of Human Neutrophil Elastase by Erythromycin and Flurythromycin, Two Macrolide Antibiotics

Inhibition of Human Neutrophil Elastase by Erythromycin and Flurythromycin, Two Macrolide Antibiotics

by Gorrini, Marina, Lupi, Anna, Viglio, Simona, Pamparana, Franco, Cetta, Giuseppe, Iadarola, Paolo, Powers, James C, Luisetti, Maurizio
Published in American journal of respiratory cell and molecular biology (01.10.2001)

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Recombinant Human Granzyme A Binds to Two Putative HLA-Associated Proteins and Cleaves One of them

Recombinant Human Granzyme A Binds to Two Putative HLA-Associated Proteins and Cleaves One of them

by Beresford, Paul J., Kam, Chih-Min, Powers, James C., Lieberman, Judy
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.1997)

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Human leukocyte and porcine pancreatic elastase: x-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors

Human leukocyte and porcine pancreatic elastase: x-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors

by Bode, Wolfram, Meyer, Edgar, Powers, James C
Published in Biochemistry (Easton) (07.03.1989)

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Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin

Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin

by Shen, Aimee, Bogyo, Matthew, Lupardus, Patrick J, Albrow, Victoria E, Guzzetta, Andrew, Powers, James C, Garcia, K Christopher
Published in Nature chemical biology (01.07.2009)

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Irreversible inhibition of serine proteases by peptide derivatives of (.alpha.-aminoalkyl)phosphonate diphenyl esters

Irreversible inhibition of serine proteases by peptide derivatives of (.alpha.-aminoalkyl)phosphonate diphenyl esters

by Oleksyszyn, Jozef, Powers, James C
Published in Biochemistry (Easton) (15.01.1991)

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Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex

Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex

by Vinitsky, Alexander, Michaud, Charlene, Powers, James C, Orlowski, Marian
Published in Biochemistry (Easton) (01.10.1992)

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Fluorescently labeled inhibitors detect localized serine protease activities in Drosophila melanogaster pole cells, embryos, and ovarian egg chambers

Fluorescently labeled inhibitors detect localized serine protease activities in Drosophila melanogaster pole cells, embryos, and ovarian egg chambers

by Jakobsen, Rasmus Kragh, Ono, Shin, Powers, James C, DeLotto, Robert
Published in Histochemistry and cell biology (01.01.2005)

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Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis

Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis

by Lentz, Christian S, Ordonez, Alvaro A, Kasperkiewicz, Paulina, La Greca, Florencia, O’Donoghue, Anthony J, Schulze, Christopher J, Powers, James C, Craik, Charles S, Drag, Marcin, Jain, Sanjay K, Bogyo, Matthew
Published in ACS infectious diseases (11.11.2016)

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Peptidyl α-Ketoamides with Nucleobases, Methylpiperazine, and Dimethylaminoalkyl Substituents as Calpain Inhibitors

Peptidyl α-Ketoamides with Nucleobases, Methylpiperazine, and Dimethylaminoalkyl Substituents as Calpain Inhibitors

by Ovat, Asli, Li, Zhao Zhao, Hampton, Christina Y, Asress, Seneshaw A, Fernández, Facundo M, Glass, Jonathan D, Powers, James C
Published in Journal of medicinal chemistry (09.09.2010)

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Synthesis and Evaluation of Diphenyl Phosphonate Esters as Inhibitors of the Trypsin-like Granzymes A and K and Mast Cell Tryptase

Synthesis and Evaluation of Diphenyl Phosphonate Esters as Inhibitors of the Trypsin-like Granzymes A and K and Mast Cell Tryptase

by Jackson, Delwin S, Fraser, Stephanie A, Ni, Li-Ming, Kam, Chih-Min, Winkler, Ulrike, Johnson, David A, Froelich, Christopher J, Hudig, Dorothy, Powers, James C
Published in Journal of medicinal chemistry (18.06.1998)

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Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and -10

Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and -10

by Ekici, Özlem Doǧan, Li, Zhao Zhao, Campbell, Amy J, James, Karen Ellis, Asgian, Juliana L, Mikolajczyk, Jowita, Salvesen, Guy S, Ganesan, Rajkumar, Jelakovic, Stjepan, Grütter, Markus G, Powers, James C
Published in Journal of medicinal chemistry (21.09.2006)

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