Prolyl hydroxylase inhibitor desidustat attenuates autoimmune hemolytic anemia in mice
Patel, Vishal J., Joharapurkar, Amit A., Kshirsagar, Samadhan G., Patel, Maulik S., Savsani, Hardikkumar H., Rakhasiya, Milan H., Dodiya, Harshad S., Jain, Mukul R.
Published in International immunopharmacology (05.12.2024)
Published in International immunopharmacology (05.12.2024)
Get full text
Journal Article
Effects of adverse childhood experiences on university students' ability to lead healthy lives: an exploratory qualitative study in Lahore, Pakistan
Fatima, Rabia, Saleem, Javeria, Ishaq, Muhammad, Khan, Humera Zaib, Javaid Bukhari, Gul Mehar, Naz, Mahwish, Fatima, Aneela, Abdi, Gholamreza, Jain, Mukul
Published in BMC public health (21.10.2024)
Published in BMC public health (21.10.2024)
Get full text
Journal Article
Overcoming Prohibitively Large Radiofrequency Demands for the Measurement of Internuclear Distances with Solid-State NMR under Fast Magic-Angle Spinning
Jain, Mukul G, Rajalakshmi, G, Madhu, P. K, Agarwal, Vipin, Mote, Kaustubh R
Published in The journal of physical chemistry. B (27.02.2020)
Published in The journal of physical chemistry. B (27.02.2020)
Get full text
Journal Article
Selection of solvent and positive control concentration for enhanced Ames test conditions for N-nitrosamine compounds
Kajavadara, Chetan K., Patel, Satyam N., Shukla, Rushikesh M., Valani, Darshan T., Patel, Rajesh J., Bhatt, Laxit K., Sundar, Rajesh, Jain, Mukul R.
Published in Regulatory toxicology and pharmacology (01.12.2024)
Published in Regulatory toxicology and pharmacology (01.12.2024)
Get full text
Journal Article
ZYKR1, a novel, potent, and peripherally selective kappa opioid receptor agonist reduces visceral pain and pruritus in animal models
Jain, Mukul R., Patel, Rakesh B., Prajapati, Kanaiyalal D., Vyas, Purvi, Bandyopadhyay, Debdutta, Prajapati, Vijay, Bahekar, Rajesh, Patel, Prakash N., Kawade, Harish M., Kokare, Dadasaheb M., Pawar, Vishwanath, Desai, Ranjit
Published in European journal of pharmacology (05.06.2022)
Published in European journal of pharmacology (05.06.2022)
Get full text
Journal Article
Desidustat: a novel PHD inhibitor for the treatment of CKD-induced anemia
Joharapurkar, Amit, Pandya, Vrajesh, Patel, Harilal, Jain, Mukul, Desai, Ranjit
Published in Frontiers in Nephrology (Online) (22.10.2024)
Published in Frontiers in Nephrology (Online) (22.10.2024)
Get full text
Journal Article
Prolyl hydroxylase inhibitor desidustat protects against acute and chronic kidney injury by reducing inflammatory cytokines and oxidative stress
Joharapurkar, Amit A., Patel, Vishal J., Kshirsagar, Samadhan G., Patel, Maulik S., Savsani, Hardikkumar H., Jain, Mukul R.
Published in Drug development research (01.09.2021)
Published in Drug development research (01.09.2021)
Get full text
Journal Article
Pharmacokinetics, Safety, and Tolerability of Saroglitazar (ZYH1), a Predominantly PPARα Agonist with Moderate PPARγ Agonist Activity in Healthy Human Subjects
Jani, Rajendra H., Kansagra, Kevinkumar, Jain, Mukul R., Patel, Harilal
Published in Clinical drug investigation (01.11.2013)
Published in Clinical drug investigation (01.11.2013)
Get full text
Journal Article
Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes
Pola, Suresh, Shah, Shailesh R., Pingali, Harikishore, Zaware, Pandurang, Thube, Baban, Makadia, Pankaj, Patel, Hoshang, Bandyopadhyay, Debdutta, Rath, Akshyaya, Giri, Suresh, Patel, Jitendra H., Ranvir, R.K., Sundar, S.R., Patel, Harilal, Kumar, Jeevan, Jain, Mukul R.
Published in Bioorganic & medicinal chemistry (01.04.2021)
Published in Bioorganic & medicinal chemistry (01.04.2021)
Get full text
Journal Article
HIF Stabilizer Desidustat Protects against Complement-Mediated Diseases
Patel, Vishal J, Joharapurkar, Amit A, Kshirsagar, Samadhan G, Patel, Maulik S, Savsani, Hardikkumar H, Dodiya, Harshad S, Rakhasiya, Milan H, Patel, Ashvin K, Sundar, Rajesh, Jain, Mukul R
Published in Drug research (01.09.2024)
Published in Drug research (01.09.2024)
Get more information
Journal Article
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral NLRP3 Inflammasome Inhibitor ZYIL1: First‐in‐Human Phase 1 Studies (Single Ascending Dose and Multiple Ascending Dose)
Parmar, Deven V., Kansagra, Kevinkumar A., Momin, Taufik, Patel, Hardik B., Jansari, Gaurav A., Bhavsar, Jay, Shah, Chintan, Patel, Jayesh M., Ghoghari, Ashok, Barot, Ajay, Sharma, Bhavesh, Viswanathan, Kasinath, Patel, Harilal V., Jain, Mukul R.
Published in Clinical pharmacology in drug development (01.02.2023)
Published in Clinical pharmacology in drug development (01.02.2023)
Get full text
Journal Article
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats
Bhatt, Laxit K, Shah, Chitrang R, Patel, Jitendra H, Rajwadi, Viral I, Dwivedi, Pankaj, Patel, Rajesh J, Ranvir, Ramchandra K, Patel, Harilal, Sundar, Rajesh, Jain, Mukul R
Published in International journal of toxicology (01.10.2024)
Published in International journal of toxicology (01.10.2024)
Get more information
Journal Article
Comparison of different QT correction methods for nonclinical safety assessment in ketamine-anesthetized Indian rhesus monkeys (Macaca mulatta)
Bhatt, Laxit K., Shah, Chitrang R., Patel, Rajesh J., Patel, Shital D., Patel, Sudhir R., Patel, Vipul A., Patel, Jitendra H., Dwivedi, Pankaj, Shah, Niraj A., Sundar, Rajesh S., Jain, Mukul R.
Published in Toxicology mechanisms and methods (24.07.2023)
Published in Toxicology mechanisms and methods (24.07.2023)
Get full text
Journal Article
Phase I Clinical Study of ZYAN1, A Novel Prolyl-Hydroxylase (PHD) Inhibitor to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Oral Administration in Healthy Volunteers
Kansagra, Kevinkumar A., Parmar, Deven, Jani, Rajendra H., Srinivas, Nuggehally R., Lickliter, Jason, Patel, Harilal V., Parikh, Devang P., Heading, Heather, Patel, Hardik B., Gupta, Rahul J., Shah, Chintan Y., Patel, Maulik R., Dholakia, Vyom N., Sukhadiya, Raghav, Jain, Mukul R., Parmar, Krupi V., Barot, Kinjal
Published in Clinical pharmacokinetics (01.01.2018)
Published in Clinical pharmacokinetics (01.01.2018)
Get full text
Journal Article
Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
Joharapurkar, Amit A, Dhanesha, Nirav A, Jain, Mukul R
Published in Diabetes, metabolic syndrome and obesity (01.01.2014)
Published in Diabetes, metabolic syndrome and obesity (01.01.2014)
Get full text
Journal Article
Balanced Coagonist of GLP-1 and Glucagon Receptors Corrects Dyslipidemia by Improving FGF21 Sensitivity in Hamster Model
Patel, Vishal, Joharapurkar, Amit, Kshirsagar, Samadhan, Patel, Hiren M, Pandey, Dheerendra, Patel, Dipam, Sutariya, Brijesh, Patel, Maulik, Bahekar, Rajesh, Jain, Mukul R
Published in Drug research (01.12.2017)
Published in Drug research (01.12.2017)
Get more information
Journal Article
Discovery of N‑Cyano-sulfoximineurea Derivatives as Potent and Orally Bioavailable NLRP3 Inflammasome Inhibitors
Agarwal, Sameer, Sasane, Santosh, Shah, Hardik A, Pethani, Jignesh P, Deshmukh, Prashant, Vyas, Vismit, Iyer, Pravin, Bhavsar, Harsh, Viswanathan, Kasinath, Bandyopadhyay, Debdutta, Giri, Poonam, Mahapatra, Jogeswar, Chatterjee, Abhijit, Jain, Mukul R, Sharma, Rajiv
Published in ACS medicinal chemistry letters (09.04.2020)
Published in ACS medicinal chemistry letters (09.04.2020)
Get full text
Journal Article
Central and Peripheral Glucagon Reduces Hyperlipidemia in Rats and Hamsters
Patel, Vishal, Joharapurkar, Amit, Kshirsagar, Samadhan, Patel, Hiren M, Pandey, Dheerendra, Patel, Dipam, Shah, Kiran, Bahekar, Rajesh, Shah, Gaurang B, Jain, Mukul R
Published in Drug research (01.06.2017)
Published in Drug research (01.06.2017)
Get more information
Journal Article