The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease
Kumar, Divya P., Caffrey, Rebecca, Marioneaux, Jonathon, Santhekadur, Prasanna K., Bhat, Madhavi, Alonso, Cristina, Koduru, Srinivas V., Philip, Binu, Jain, Mukul R., Giri, Suresh R., Bedossa, Pierre, Sanyal, Arun J.
Published in Scientific reports (09.06.2020)
Published in Scientific reports (09.06.2020)
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Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet
Giri, Suresh R, Bhoi, Bibhuti, Trivedi, Chitrang, Rath, Akshyaya, Rathod, Rohan, Sharma, Anish, Ranvir, Ramchandra, Kadam, Shekhar, Ingale, Kailash, Patel, Hiren, Nyska, Abraham, Jain, Mukul R
Published in BMC cancer (17.01.2023)
Published in BMC cancer (17.01.2023)
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Prolyl hydroxylase inhibitor desidustat protects against acute and chronic kidney injury by reducing inflammatory cytokines and oxidative stress
Joharapurkar, Amit A., Patel, Vishal J., Kshirsagar, Samadhan G., Patel, Maulik S., Savsani, Hardikkumar H., Jain, Mukul R.
Published in Drug development research (01.09.2021)
Published in Drug development research (01.09.2021)
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Comparison of different QT correction methods for nonclinical safety assessment in ketamine-anesthetized Indian rhesus monkeys (Macaca mulatta)
Bhatt, Laxit K., Shah, Chitrang R., Patel, Rajesh J., Patel, Shital D., Patel, Sudhir R., Patel, Vipul A., Patel, Jitendra H., Dwivedi, Pankaj, Shah, Niraj A., Sundar, Rajesh S., Jain, Mukul R.
Published in Toxicology mechanisms and methods (24.07.2023)
Published in Toxicology mechanisms and methods (24.07.2023)
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Journal Article
ZY12201, A Potent TGR5 Agonist: Identification of a Novel Pan CYP450 Inhibitor Tool Compound for In-Vitro Assessment
Giri, Poonam, Gupta, Lakshmikant, Rathod, Anil, Joshi, Vipul, Giri, Shyamkumar, Patel, Nirmal, Agarwal, Sameer, R Jain, Mukul
Published in Drug metabolism letters (15.03.2022)
Published in Drug metabolism letters (15.03.2022)
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Effect of GLP-1 based therapies on diabetic dyslipidemia
Patel, Vishal J, Joharapurkar, Amit A, Shah, Gaurang B, Jain, Mukul R
Published in Current diabetes reviews (01.01.2014)
Published in Current diabetes reviews (01.01.2014)
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Journal Article
Hematological and biochemical reference intervals of wild-caught and inhouse adult Indian rhesus macaques (Macaca mulatta)
Shah, Niraj A., Bhatt, Laxit K., Patel, Rajesh J., Patel, Tushar M., Patel, Nayankumar V., Trivedi, Harshida G., Patel, Nilam R., Patel, Jitendra H., Patel, Satish D., Sundar, Rajesh S., Jain, Mukul R.
Published in Laboratory animal research (11.11.2022)
Published in Laboratory animal research (11.11.2022)
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Synthesis and antidiabetic activity of 2,5-disubstituted-3-imidazol-2-yl-pyrrolo[2,3- b]pyridines and thieno[2,3- b]pyridines
Bahekar, Rajesh H., Jain, Mukul R., Jadav, Pradip A., Prajapati, Vijay M., Patel, Dipam N., Gupta, Arun A., Sharma, Ajay, Tom, Robby, Bandyopadhya, Debdutta, Modi, Honey, Patel, Pankaj R.
Published in Bioorganic & medicinal chemistry (01.11.2007)
Published in Bioorganic & medicinal chemistry (01.11.2007)
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Prolyl hydroxylase inhibitor desidustat improves anemia in erythropoietin hyporesponsive state
Joharapurkar, Amit A., Patel, Vishal J., Kshirsagar, Samadhan G., Patel, Maulik S., Savsani, Hardikkumar H., Kajavadara, Chetan, Valani, Darshan, Jain, Mukul R.
Published in Current research in pharmacology and drug discovery (2022)
Published in Current research in pharmacology and drug discovery (2022)
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Journal Article
Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone
Patel, Vishal J, Joharapurkar, Amit A, Kshirsagar, Samadhan G, Sutariya, Brijesh K, Patel, Maulik S, Bahekar, Rajesh H, Jain, Mukul R
Published in Current molecular pharmacology (01.01.2019)
Published in Current molecular pharmacology (01.01.2019)
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Design, synthesis, and biological evaluation of substituted- N-(thieno[2,3- b]pyridin-3-yl)-guanidines, N-(1 H-pyrrolo[2,3- b]pyridin-3-yl)-guanidines, and N-(1 H-indol-3-yl)-guanidines
Bahekar, Rajesh H., Jain, Mukul R., Goel, Ashish, Patel, Dipam N., Prajapati, Vijay M., Gupta, Arun A., Jadav, Pradip A., Patel, Pankaj R.
Published in Bioorganic & medicinal chemistry (01.05.2007)
Published in Bioorganic & medicinal chemistry (01.05.2007)
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Journal Article
Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models
Jain, Mukul R., Giri, Suresh R., Bhoi, Bibhuti, Trivedi, Chitrang, Rath, Akshyaya, Rathod, Rohan, Ranvir, Ramchandra, Kadam, Shekhar, Patel, Hiren, Swain, Prabodha, Roy, Sib Sankar, Das, Nabanita, Karmakar, Eshani, Wahli, Walter, Patel, Pankaj R.
Published in Liver international (01.06.2018)
Published in Liver international (01.06.2018)
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Efficient Synthesis of Unsymmetrical Dibenzothiophenes by Acid-Mediated Intramolecular Cyclization of Biaryl Methyl Sulfoxides
Pandya, Vrajesh B., Jain, Mukul R., Chaugule, Balaji V., Patel, Jigar S., Parmar, Bhavesh M., Joshi, Jignesh K., Patel, Pankaj R.
Published in Synthetic communications (15.02.2012)
Published in Synthetic communications (15.02.2012)
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Journal Article
Effect of fasting duration on clinical pathology results in Wistar rats
Kale, Vijay P, Joshi, Girish S, Gohil, Parikshit B, Jain, Mukul R
Published in Veterinary clinical pathology (01.09.2009)
Published in Veterinary clinical pathology (01.09.2009)
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Journal Article
Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor
Agarwal, Sameer, Pethani, Jignesh P., Shah, Hardik A., Vyas, Vismit, Sasane, Santosh, Bhavsar, Harsh, Bandyopadhyay, Debdutta, Giri, Poonam, Viswanathan, Kasinath, Jain, Mukul R., Sharma, Rajiv
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
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Simultaneous determination of sacubitrilat and fimasartan in rat plasma by a triple quad liquid chromatography–tandem mass spectrometry method utilizing electrospray ionization in positive mode
Giri, Poonam, Joshi, Vipul, Giri, Shyamkumar, Delvadia, Prashant, Jain, Mukul R.
Published in Biomedical chromatography (01.02.2021)
Published in Biomedical chromatography (01.02.2021)
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Journal Article
HIF-PHD inhibitor desidustat ameliorates iron deficiency anemia
Patel, Vishal J., Joharapurkar, Amit, Kshirsagar, Samadhan G., Patel, Maulik S., Savsani, Hardikkumar H., Dodiya, Harshad S., Rakhasiya, Milan H., Kajavadara, Chetan, Valani, Darshan, Jain, Mukul R.
Published in Toxicology and applied pharmacology (01.02.2024)
Published in Toxicology and applied pharmacology (01.02.2024)
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