Charting a dynamic DNA methylation landscape of the human genome
Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Philip L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas, Meissner, Alexander
Published in Nature (London) (22.08.2013)
Published in Nature (London) (22.08.2013)
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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
Ng, Bernard, White, Charles C, Klein, Hans-Ulrich, Sieberts, Solveig K, McCabe, Cristin, Patrick, Ellis, Xu, Jishu, Yu, Lei, Gaiteri, Chris, Bennett, David A, Mostafavi, Sara, De Jager, Philip L
Published in Nature neuroscience (01.10.2017)
Published in Nature neuroscience (01.10.2017)
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Journal Article
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain
Felsky, Daniel, Roostaei, Tina, Nho, Kwangsik, Risacher, Shannon L., Bradshaw, Elizabeth M., Petyuk, Vlad, Schneider, Julie A., Saykin, Andrew, Bennett, David A., De Jager, Philip L.
Published in Nature communications (24.01.2019)
Published in Nature communications (24.01.2019)
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Journal Article
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
Villani, Alexandra-Chloé, Satija, Rahul, Reynolds, Gary, Sarkizova, Siranush, Shekhar, Karthik, Fletcher, James, Griesbeck, Morgane, Butler, Andrew, Zheng, Shiwei, Lazo, Suzan, Jardine, Laura, Dixon, David, Stephenson, Emily, Nilsson, Emil, Grundberg, Ida, McDonald, David, Filby, Andrew, Li, Weibo, De Jager, Philip L., Rozenblatt-Rosen, Orit, Lane, Andrew A., Haniffa, Muzlifah, Regev, Aviv, Hacohen, Nir
Published in Science (American Association for the Advancement of Science) (21.04.2017)
Published in Science (American Association for the Advancement of Science) (21.04.2017)
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Journal Article
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
Mathys, Hansruedi, Adaikkan, Chinnakkaruppan, Gao, Fan, Young, Jennie Z., Manet, Elodie, Hemberg, Martin, De Jager, Philip L., Ransohoff, Richard M., Regev, Aviv, Tsai, Li-Huei
Published in Cell reports (Cambridge) (10.10.2017)
Published in Cell reports (Cambridge) (10.10.2017)
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Journal Article
Parkinson's disease: genetics and pathogenesis
Shulman, Joshua M, De Jager, Philip L, Feany, Mel B
Published in Annual review of pathology (01.01.2011)
Published in Annual review of pathology (01.01.2011)
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Journal Article
Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
Gaublomme, Jellert T., Li, Bo, McCabe, Cristin, Knecht, Abigail, Yang, Yiming, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Waldman, Julia, Dionne, Danielle, Nguyen, Lan, De Jager, Philip L., Yeung, Bertrand, Zhao, Xinfang, Habib, Naomi, Rozenblatt-Rosen, Orit, Regev, Aviv
Published in Nature communications (02.07.2019)
Published in Nature communications (02.07.2019)
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Journal Article
Parsing the Interferon Transcriptional Network and Its Disease Associations
Mostafavi, Sara, Yoshida, Hideyuki, Moodley, Devapregasan, LeBoité, Hugo, Rothamel, Katherine, Raj, Towfique, Ye, Chun Jimmie, Chevrier, Nicolas, Zhang, Shen-Ying, Feng, Ting, Lee, Mark, Casanova, Jean-Laurent, Clark, James D., Hegen, Martin, Telliez, Jean-Baptiste, Hacohen, Nir, De Jager, Philip L., Regev, Aviv, Mathis, Diane, Benoist, Christophe
Published in Cell (28.01.2016)
Published in Cell (28.01.2016)
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Journal Article
Brain proteome-wide association study implicates novel proteins in depression pathogenesis
Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Gockley, Jake, Logsdon, Benjamin A., Duong, Duc M., Dammer, Eric B., Lori, Adriana, Kim, Paul J., Ressler, Kerry J., Beach, Thomas G., Reiman, Eric M., Epstein, Michael P., De Jager, Philip L., Lah, James J., Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.
Published in Nature neuroscience (01.06.2021)
Published in Nature neuroscience (01.06.2021)
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Journal Article
Alterations of the human gut microbiome in multiple sclerosis
Jangi, Sushrut, Gandhi, Roopali, Cox, Laura M., Li, Ning, von Glehn, Felipe, Yan, Raymond, Patel, Bonny, Mazzola, Maria Antonietta, Liu, Shirong, Glanz, Bonnie L., Cook, Sandra, Tankou, Stephanie, Stuart, Fiona, Melo, Kirsy, Nejad, Parham, Smith, Kathleen, Topçuolu, Begüm D., Holden, James, Kivisäkk, Pia, Chitnis, Tanuja, De Jager, Philip L., Quintana, Francisco J., Gerber, Georg K., Bry, Lynn, Weiner, Howard L.
Published in Nature communications (28.06.2016)
Published in Nature communications (28.06.2016)
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Journal Article
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease
Mahoney, Emily R., Dumitrescu, Logan, Moore, Annah M., Cambronero, Francis E., De Jager, Philip L., Koran, Mary Ellen I., Petyuk, Vladislav A., Robinson, Renã A. S., Goyal, Sandeep, Schneider, Julie A., Bennett, David A., Jefferson, Angela L., Hohman, Timothy J.
Published in Molecular psychiatry (01.03.2021)
Published in Molecular psychiatry (01.03.2021)
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Journal Article
Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
Chun, Sung, Casparino, Alexandra, Patsopoulos, Nikolaos A, Croteau-Chonka, Damien C, Raby, Benjamin A, De Jager, Philip L, Sunyaev, Shamil R, Cotsapas, Chris
Published in Nature genetics (01.04.2017)
Published in Nature genetics (01.04.2017)
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Journal Article
Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues
Zhu, Jiang, Adli, Mazhar, Zou, James Y., Verstappen, Griet, Coyne, Michael, Zhang, Xiaolan, Durham, Timothy, Miri, Mohammad, Deshpande, Vikram, De Jager, Philip L., Bennett, David A., Houmard, Joseph A., Muoio, Deborah M., Onder, Tamer T., Camahort, Ray, Cowan, Chad A., Meissner, Alexander, Epstein, Charles B., Shoresh, Noam, Bernstein, Bradley E.
Published in Cell (31.01.2013)
Published in Cell (31.01.2013)
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Journal Article
A transcriptomic atlas of aged human microglia
Olah, Marta, Patrick, Ellis, Villani, Alexandra-Chloe, Xu, Jishu, White, Charles C., Ryan, Katie J., Piehowski, Paul, Kapasi, Alifiya, Nejad, Parham, Cimpean, Maria, Connor, Sarah, Yung, Christina J., Frangieh, Michael, McHenry, Allison, Elyaman, Wassim, Petyuk, Vlad, Schneider, Julie A., Bennett, David A., De Jager, Philip L., Bradshaw, Elizabeth M.
Published in Nature communications (07.02.2018)
Published in Nature communications (07.02.2018)
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Journal Article
Gut Microbiome in Progressive Multiple Sclerosis
Cox, Laura M., Maghzi, Amir Hadi, Liu, Shirong, Tankou, Stephanie K., Dhang, Fyonn H., Willocq, Valerie, Song, Anya, Wasén, Caroline, Tauhid, Shahamat, Chu, Renxin, Anderson, Mark C., De Jager, Philip L., Polgar‐Turcsanyi, Mariann, Healy, Brian C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Weiner, Howard L.
Published in Annals of neurology (01.06.2021)
Published in Annals of neurology (01.06.2021)
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Journal Article
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Lunnon, Katie, Smith, Rebecca, Hannon, Eilis, De Jager, Philip L, Srivastava, Gyan, Volta, Manuela, Troakes, Claire, Al-Sarraj, Safa, Burrage, Joe, Macdonald, Ruby, Condliffe, Daniel, Harries, Lorna W, Katsel, Pavel, Haroutunian, Vahram, Kaminsky, Zachary, Joachim, Catharine, Powell, John, Lovestone, Simon, Bennett, David A, Schalkwyk, Leonard C, Mill, Jonathan
Published in Nature neuroscience (01.09.2014)
Published in Nature neuroscience (01.09.2014)
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Journal Article
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Farh, Kyle Kai-How, Marson, Alexander, Zhu, Jiang, Kleinewietfeld, Markus, Housley, William J., Beik, Samantha, Shoresh, Noam, Whitton, Holly, Ryan, Russell J. H., Shishkin, Alexander A., Hatan, Meital, Carrasco-Alfonso, Marlene J., Mayer, Dita, Luckey, C. John, Patsopoulos, Nikolaos A., De Jager, Philip L., Kuchroo, Vijay K., Epstein, Charles B., Daly, Mark J., Hafler, David A., Bernstein, Bradley E.
Published in Nature (London) (19.02.2015)
Published in Nature (London) (19.02.2015)
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Journal Article
Natural selection in mimicry
Anderson, Bruce, Jager, Marinus L.
Published in Biological reviews of the Cambridge Philosophical Society (01.04.2020)
Published in Biological reviews of the Cambridge Philosophical Society (01.04.2020)
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