Prodrugs: design and clinical applications
Rautio, Jarkko, Kumpulainen, Hanna, Heimbach, Tycho, Oliyai, Reza, Oh, Dooman, Järvinen, Tomi, Savolainen, Jouko
Published in Nature reviews. Drug discovery (01.03.2008)
Published in Nature reviews. Drug discovery (01.03.2008)
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Journal Article
Antimicrobial activity of piperazine derivatives of chitosan
Másson, Már, Holappa, Jukka, Hjálmarsdóttir, Martha, Rúnarsson, Ögmundur V., Nevalainen, Tapio, Järvinen, Tomi
Published in Carbohydrate polymers (04.11.2008)
Published in Carbohydrate polymers (04.11.2008)
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Journal Article
In vitro toxicity and permeation of cyclodextrins in Calu-3 cells
Matilainen, Laura, Toropainen, Tarja, Vihola, Henna, Hirvonen, Jouni, Järvinen, Tomi, Jarho, Pekka, Järvinen, Kristiina
Published in Journal of controlled release (18.02.2008)
Published in Journal of controlled release (18.02.2008)
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Journal Article
In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs
Garnier, Tracy, Mäntylä, Antti, Järvinen, Tomi, Lawrence, Jayne, Brown, Marc, Croft, Simon
Published in Journal of antimicrobial chemotherapy (01.10.2007)
Published in Journal of antimicrobial chemotherapy (01.10.2007)
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Journal Article
The Effect of Cyclodextrins on Chemical and Physical Stability of Glucagon and Characterization of Glucagon/γ-CD Inclusion Complexes
Matilainen, Laura, Larsen, Kim Lambertsen, Wimmer, Reinhard, Keski-Rahkonen, Pekka, Auriola, Seppo, Järvinen, Tomi, Jarho, Pekka
Published in Journal of pharmaceutical sciences (01.07.2008)
Published in Journal of pharmaceutical sciences (01.07.2008)
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Journal Article
Synthesis of Novel Quaternary Chitosan Derivatives via N-Chloroacyl- 6-O-triphenylmethylchitosans
Holappa, Jukka, Nevalainen, Tapio, Soininen, Pasi, Masson, Mar, Jaervinen, Tomi
Published in Biomacromolecules (01.01.2006)
Published in Biomacromolecules (01.01.2006)
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Journal Article
Novel Water-Soluble Quaternary Piperazine Derivatives of Chitosan: Synthesis and Characterization
Holappa, Jukka, Nevalainen, Tapio, Safin, Rustam, Soininen, Pasi, Asplund, Tomas, Luttikhedde, Tiina, Másson, Már, Järvinen, Tomi
Published in Macromolecular bioscience (10.02.2006)
Published in Macromolecular bioscience (10.02.2006)
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Journal Article
Novel cyclic phosphate prodrug approach for cytochrome p450-activated drugs containing an alcohol functionality
HUTTUNEN, Kristiina M, MÄHÖNEN, Niina, LEPPÄNEN, Jukka, VEPSÄLÄINEN, Jouko, JUVONEN, Risto O, RAUNIO, Hannu, KUMPULAINEN, Hanna, JÄRVINEN, Tomi, RAUTIO, Jarkko
Published in Pharmaceutical research (01.04.2007)
Published in Pharmaceutical research (01.04.2007)
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Journal Article
N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors
Kiviranta, Päivi H., Leppänen, Jukka, Rinne, Valtteri M., Suuronen, Tiina, Kyrylenko, Olga, Kyrylenko, Sergiy, Kuusisto, Erkki, Tervo, Anu J., Järvinen, Tomi, Salminen, Antero, Poso, Antti, Wallén, Erik A.A.
Published in Bioorganic & medicinal chemistry letters (01.05.2007)
Published in Bioorganic & medicinal chemistry letters (01.05.2007)
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Journal Article
Design, Synthesis, and In Vitro Evaluation of Carbamate Derivatives of 2-Benzoxazolyl- and 2-Benzothiazolyl-(3-hydroxyphenyl)-methanones as Novel Fatty Acid Amide Hydrolase Inhibitors
Myllymäki, Mikko J, Saario, Susanna M, Kataja, Antti O, Castillo-Melendez, Joel A, Nevalainen, Tapio, Juvonen, Risto O, Järvinen, Tomi, Koskinen, Ari M. P
Published in Journal of medicinal chemistry (15.11.2007)
Published in Journal of medicinal chemistry (15.11.2007)
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Journal Article
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide
Parkkari, Teija, Savinainen, Juha R., Raitio, Katri H., Saario, Susanna M., Matilainen, Laura, Sirviö, Tuomas, Laitinen, Jarmo T., Nevalainen, Tapio, Niemi, Riku, Järvinen, Tomi
Published in Bioorganic & medicinal chemistry (01.08.2006)
Published in Bioorganic & medicinal chemistry (01.08.2006)
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Journal Article
Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE)
Parkkari, Teija, Salo, Outi M.H., Huttunen, Kristiina M., Savinainen, Juha R., Laitinen, Jarmo T., Poso, Antti, Nevalainen, Tapio, Järvinen, Tomi
Published in Bioorganic & medicinal chemistry (15.04.2006)
Published in Bioorganic & medicinal chemistry (15.04.2006)
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Journal Article
An introduction of a pyridine group into the structure of prolyl oligopeptidase inhibitors
Jarho, Elina M., Venäläinen, Jarkko I., Juntunen, Juha, Yli-Kokko, A. Leena, Vepsäläinen, Jouko, Christiaans, Johannes A.M., Forsberg, Markus M., Järvinen, Tomi, Männistö, Pekka T., Wallén, Erik A.A.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
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Journal Article
α-Methylated derivatives of 2-arachidonoyl glycerol: Synthesis, CB1 receptor activity, and enzymatic stability
Parkkari, Teija, Myllymäki, Mikko, Savinainen, Juha R., Saario, Susanna M., Castillo-Meléndez, Joel A., Laitinen, Jarmo T., Nevalainen, Tapio, Koskinen, Ari M.P., Järvinen, Tomi
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Journal Article