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Published in Bioorganic & medicinal chemistry letters (05.07.1999)
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Published in Bioorganic & medicinal chemistry letters (2008)
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Identification and optimization of N3,N6-diaryl-lH-pyrazolo[3,4-d] pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors
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Published in Bioorganic & medicinal chemistry letters (2008)
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Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors
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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1
Tu, Hua, Powers, Jay P, Liu, Jinsong, Ursu, Stefania, Sudom, Athena, Yan, Xuelei, Xu, Haoda, Meininger, David, Degraffenreid, Michael, He, Xiao, Jaen, Juan C, Sun, Daqing, Labelle, Marc, Yamamoto, Hiroshi, Shan, Bei, Walker, Nigel P C, Wang, Zhulun
Published in Bioorganic & medicinal chemistry (01.10.2008)
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Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)
Sun, Daqing, Wang, Zhulun, Di, Yongmei, Jaen, Juan C, Labelle, Marc, Ma, Ji, Miao, Shichang, Sudom, Athena, Tang, Liang, Tomooka, Craig S, Tu, Hua, Ursu, Stefania, Walker, Nigel, Yan, Xuelei, Ye, Qiuping, Powers, Jay P
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Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model
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Synthesis and evaluation of 2-aryl-4H-3,1-benzoxazin-4-ones as C1r serine protease inhibitors
Gilmore, John L., Hays, Sheryl J., Caprathe, Bradley W., Lee, Chitase, Emmerling, Mark R., Michael, Walter, Jaen, Juan C.
Published in Bioorganic & medicinal chemistry letters (19.03.1996)
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Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist
Tecle, Haile, Barrett, Stephen D, Lauffer, David J, Augelli-Szafran, Corinne, Brann, Mark R, Callahan, Michael J, Caprathe, Bradley. W, Davis, Robert E, Doyle, Patricia D, Eubanks, David, Lipiniski, William, Mirzadegan, Tara, Moos, Walter H, Moreland, D. W, Nelson, Carrie B, Pavia, Michael R, Raby, Charlotte, Schwarz, Roy D, Spencer, Carolyn J, Thomas, Anthony J, Jaen, Juan C
Published in Journal of medicinal chemistry (02.07.1998)
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Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease
Plummer, Janet S., Cai, Cuiman, Hays, Sheryl J., Gilmore, John L., Emmerling, Mark R., Michael, Walter, Narasimhan, Lakshmi S., Watson, M.Desiree, Wang, Kevin, Nath, Rathna, Evans, Lori M., Jaen, Juan C.
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
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Zhang, Penglie, Malathong, Viengkham, Li, Yandong, Powers, Jay P, Dragoli, Dean R, Fan, Pingchen, Punna, Sreenivas, Tanaka, Hiroko, Jaen, Juan C, Chen, Xi
Year of Publication 09.07.2019
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Year of Publication 05.04.2018
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Year of Publication 05.04.2018
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CHEN Xi, FAN Pingchen, LI Yandong, PUNNA Sreenivas, DRAGOLI Dean R, JAEN Juan C, ZHANG Penglie, POWERS Jay P, MALATHONG Viengkham, TANAKA Hiroko
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Year of Publication 06.12.2017
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Year of Publication 04.12.2017
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