Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models
Wang, Xiaojun, Yu, Xiaohong, Gavardinas, Kostas, Dey, Asim, Zhang, Hong Y, Porter, Gina, Porras, Leah, Yu, Lan, Guo, Haihong, Reidy, Charles A, Haas, Joseph V, Xu, Yanping, Kowala, Mark C, Jadhav, Prabhakar K, Wetterau, John R
Published in PloS one (26.01.2024)
Published in PloS one (26.01.2024)
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Copper-catalyzed general CN and CO bond cross-coupling with arylboronic acid
Lam, Patrick Y.S, Vincent, Guillaume, Clark, Charles G, Deudon, Sophie, Jadhav, Prabhakar K
Published in Tetrahedron letters (14.05.2001)
Published in Tetrahedron letters (14.05.2001)
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Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm
Jadhav, Prabhakar K, Schiffler, Matthew A, Gavardinas, Kostas, Kim, Euibong J, Matthews, Donald P, Staszak, Michael A, Coffey, D. Scott, Shaw, Bruce W, Cassidy, Kenneth C, Brier, Richard A, Zhang, Yuke, Christie, Robert M, Matter, William F, Qing, Keyun, Durbin, Jim D, Wang, Yong, Deng, Gary G
Published in ACS medicinal chemistry letters (09.10.2014)
Published in ACS medicinal chemistry letters (09.10.2014)
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Chiral synthesis via organoboranes. 13. A highly diastereoselective and enantioselective addition of [(Z)-.gamma.-alkoxyallyl]diisopinocampheylboranes to aldehydes
Brown, Herbert C, Jadhav, Prabhakar K, Bhat, Krishna S
Published in Journal of the American Chemical Society (01.03.1988)
Published in Journal of the American Chemical Society (01.03.1988)
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(S)-N-{3-[1-Cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: A Potent, Nonsteroidal, Functional Antagonist of the Mineralocorticoid Receptor
Bell, Michael G, Gernert, Douglas L, Grese, Timothy A, Belvo, Matthew D, Borromeo, Peter S, Kelley, Sally A, Kennedy, Joseph H, Kolis, Stanley P, Lander, Peter A, Richey, Rachel, Sharp, V. Scott, Stephenson, Gregory A, Williams, Jeffrey D, Yu, Hannah, Zimmerman, Karen M, Steinberg, Mitchell I, Jadhav, Prabhakar K
Published in Journal of medicinal chemistry (27.12.2007)
Published in Journal of medicinal chemistry (27.12.2007)
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ESR and X-ray Structure Investigations on the Binding and Mechanism of Inhibition of the Native State of Myeloperoxidase with Low Molecular Weight Fragments
Chavali, Balagopalakrishna, Masquelin, Thierry, Nilges, Mark J., Timm, David E., Stout, Stephanie L., Matter, William F., Jin, Najia, Jadhav, Prabhakar K., Deng, Gary G.
Published in Applied magnetic resonance (2015)
Published in Applied magnetic resonance (2015)
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SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa
SMALLHEER, Joanne M, ALEXANDER, Richard S, KNABB, Robert M, WEXLER, Ruth R, JADHAV, Prabhakar K, JIANMIN WANG, SHUAIGE WANG, NAKAJIMA, Suanne, ROSSI, Karen A, SMALLWOOD, Angela, BARBERA, Frank, BURDICK, Debra, LUETTGEN, Joseph M
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
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Cyclic Urea Amides: HIV-1 Protease Inhibitors with Low Nanomolar Potency against both Wild Type and Protease Inhibitor Resistant Mutants of HIV
Jadhav, Prabhakar K, Ala, Paul, Woerner, Francis J, Chang, Chong-Hwan, Garber, Sena S, Anton, Elizabeth D, Bacheler, Lee T
Published in Journal of medicinal chemistry (17.01.1997)
Published in Journal of medicinal chemistry (17.01.1997)
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An asymmetric synthesis of the diastereomeric 1-(2-cyclohexenyl)-1-alkanols in high optical purity via a stereochemically stable allylic borane, B-2-cyclohexen-1-yldiisopinocampheylborane
Brown, Herbert C, Jadhav, Prabhakar K, Bhat, Krishna S
Published in Journal of the American Chemical Society (01.04.1985)
Published in Journal of the American Chemical Society (01.04.1985)
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Cyclic HIV Protease Inhibitors: Design and Synthesis of Orally Bioavailable, Pyrazole P2/P2‘ Cyclic Ureas with Improved Potency
Han, Qi, Chang, Chong-Hwan, Li, Renhua, Ru, Yu, Jadhav, Prabhakar K, Lam, Patrick Y. S
Published in Journal of medicinal chemistry (04.06.1998)
Published in Journal of medicinal chemistry (04.06.1998)
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Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors
Nugiel, David A, Jacobs, Kim, Worley, Tabitha, Patel, Mona, Kaltenbach, Robert F, Meyer, Dayton T, Jadhav, Prabhakar K, De Lucca, George V, Smyser, Thomas E, Klabe, Ronald M, Bacheler, Lee T, Rayner, Marlene M, Seitz, Steven P
Published in Journal of medicinal chemistry (24.05.1996)
Published in Journal of medicinal chemistry (24.05.1996)
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3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists
Neel, David A., Brown, Matthew L., Lander, Peter A., Grese, Timothy A., Defauw, Jean M., Doti, Robert A., Fields, Todd, Kelley, Sally Ann, Smith, Stephon, Zimmerman, Karen M., Steinberg, Mitchell I., Jadhav, Prabhakar K.
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
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Synthesis of Cis and Trans Isomers of an Isoxazoline Ring-Hydroxylated Metabolite of Roxifiban, a Platelet Glycoprotein IIb/IIIa Receptor Antagonist
Batt, Douglas G, Houghton, Gregory C, Daneker, Wayne F, Jadhav, Prabhakar K
Published in Journal of organic chemistry (17.11.2000)
Published in Journal of organic chemistry (17.11.2000)
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Counteracting HIV-1 Protease Drug Resistance: Structural Analysis of Mutant Proteases Complexed with XV638 and SD146, Cyclic Urea Amides with Broad Specificities
Ala, Paul J, Huston, Edward E, Klabe, Ronald M, Jadhav, Prabhakar K, Lam, Patrick Y. S, Chang, Chong-Hwan
Published in Biochemistry (Easton) (27.10.1998)
Published in Biochemistry (Easton) (27.10.1998)
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Journal Article
Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies
Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan
Published in Journal of medicinal chemistry (23.04.1998)
Published in Journal of medicinal chemistry (23.04.1998)
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Journal Article
Molecular Recognition of Cyclic Urea HIV-1 Protease Inhibitors
Ala, Paul J., DeLoskey, Richard J., Huston, Edward E., Jadhav, Prabhakar K., Lam, Patrick Y.S., Eyermann, Charles J., Hodge, C. Nicholas, Schadt, Margaret C., Lewandowski, Frank A., Weber, Patricia C., McCabe, Denise D., Duke, Jodie L., Chang, Chong-Hwan
Published in The Journal of biological chemistry (15.05.1998)
Published in The Journal of biological chemistry (15.05.1998)
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