A Small-Molecule Dengue Virus Entry Inhibitor
WANG, Qing-Yin, PATEL, Sejal J, MEE KIAN POH, WAI YEE PHONG, KELLER, Thomas H, JACOBY, Edgar, VASUDEVAN, Subhash G, VANGREVELINGHE, Eric, HAO YING XU, RAO, Ranga, JABER, Deana, SCHUL, Wouter, FENG GU, HEUDI, Olivier, NGAI LING MA
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
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Journal Article
New Methods for Ligand-Based Virtual Screening: Use of Data Fusion and Machine Learning to Enhance the Effectiveness of Similarity Searching
Hert, Jérôme, Willett, Peter, Wilton, David J, Acklin, Pierre, Azzaoui, Kamal, Jacoby, Edgar, Schuffenhauer, Ansgar
Published in Journal of chemical information and modeling (01.03.2006)
Published in Journal of chemical information and modeling (01.03.2006)
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Journal Article
The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research
Ratnam, Joseline, Zdrazil, Barbara, Digles, Daniela, Cuadrado-Rodriguez, Emiliano, Neefs, Jean-Marc, Tipney, Hannah, Siebes, Ronald, Waagmeester, Andra, Bradley, Glyn, Chau, Chau Han, Richter, Lars, Brea, Jose, Evelo, Chris T, Jacoby, Edgar, Senger, Stefan, Loza, Maria Isabel, Ecker, Gerhard F, Chichester, Christine
Published in PloS one (18.12.2014)
Published in PloS one (18.12.2014)
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Journal Article
Probing the Bioactivity-Relevant Chemical Space of Robust Reactions and Common Molecular Building Blocks
Hartenfeller, Markus, Eberle, Martin, Meier, Peter, Nieto-Oberhuber, Cristina, Altmann, Karl-Heinz, Schneider, Gisbert, Jacoby, Edgar, Renner, Steffen
Published in Journal of chemical information and modeling (25.05.2012)
Published in Journal of chemical information and modeling (25.05.2012)
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Journal Article
Molecular Lipophilicity in Protein Modeling and Drug Design
Efremov, Roman G, Chugunov, Anton O, Pyrkov, Timothy V, Priestle, John P, Arseniev, Alexander S, Jacoby, Edgar
Published in Current medicinal chemistry (01.02.2007)
Published in Current medicinal chemistry (01.02.2007)
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Journal Article
Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor
Yu, Xiaodi, Abeywickrema, Pravien, Bonneux, Brecht, Behera, Ishani, Anson, Brandon, Jacoby, Edgar, Fung, Amy, Adhikary, Suraj, Bhaumik, Anusarka, Carbajo, Rodrigo J., De Bruyn, Suzanne, Miller, Robyn, Patrick, Aaron, Pham, Quyen, Piassek, Madison, Verheyen, Nick, Shareef, Afzaal, Sutto-Ortiz, Priscila, Ysebaert, Nina, Van Vlijmen, Herman, Jonckers, Tim H. M., Herschke, Florence, McLellan, Jason S., Decroly, Etienne, Fearns, Rachel, Grosse, Sandrine, Roymans, Dirk, Sharma, Sujata, Rigaux, Peter, Jin, Zhinan
Published in Communications biology (21.10.2023)
Published in Communications biology (21.10.2023)
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Journal Article
Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling
Wandinger, Sebastian K, Lahortiga, Idoya, Jacobs, Kris, Klammer, Martin, Jordan, Nicole, Elschenbroich, Sarah, Parade, Marc, Jacoby, Edgar, Linders, Joannes T M, Brehmer, Dirk, Cools, Jan, Daub, Henrik
Published in PloS one (08.01.2016)
Published in PloS one (08.01.2016)
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Journal Article
Library design for fragment based screening
Schuffenhauer, Ansgar, Ruedisser, Simon, Marzinzik, Andreas L, Jahnke, Wolfgang, Blommers, Marcel, Selzer, Paul, Jacoby, Edgar
Published in Current topics in medicinal chemistry (01.01.2005)
Published in Current topics in medicinal chemistry (01.01.2005)
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Journal Article
Comparison of Fingerprint-Based Methods for Virtual Screening Using Multiple Bioactive Reference Structures
Hert, Jérôme, Willett, Peter, Wilton, David J, Acklin, Pierre, Azzaoui, Kamal, Jacoby, Edgar, Schuffenhauer, Ansgar
Published in Journal of Chemical Information and Computer Sciences (01.05.2004)
Published in Journal of Chemical Information and Computer Sciences (01.05.2004)
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Journal Article
Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection
Jacoby, Edgar, Schuffenhauer, Ansgar, Popov, Maxim, Azzaoui, Kamal, Havill, Benjamin, Schopfer, Ulrich, Engeloch, Caroline, Stanek, Jaroslav, Acklin, Pierre, Rigollier, Pascal, Stoll, Friederike, Koch, Guido, Meier, Peter, Orain, David, Giger, Rudolph, Hinrichs, Jürgen, Malagu, Karine, Zimmermann, Jürg, Roth, Hans-Joerg
Published in Current topics in medicinal chemistry (01.01.2005)
Published in Current topics in medicinal chemistry (01.01.2005)
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Journal Article
The 7 TM G-Protein-Coupled Receptor Target Family
Jacoby, Edgar, Bouhelal, Rochdi, Gerspacher, Marc, Seuwen, Klaus
Published in ChemMedChem (11.08.2006)
Published in ChemMedChem (11.08.2006)
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Journal Article
An Ontology for Pharmaceutical Ligands and Its Application for in Silico Screening and Library Design
Schuffenhauer, Ansgar, Zimmermann, Jürg, Stoop, Ruedi, van der Vyver, Jan-Jan, Lecchini, Steffano, Jacoby, Edgar
Published in Journal of Chemical Information and Computer Sciences (01.07.2002)
Published in Journal of Chemical Information and Computer Sciences (01.07.2002)
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Journal Article
Direct-acting antivirals for RSV treatment, a review
Bonneux, Brecht, Jacoby, Edgar, Ceconi, Martina, Stobbelaar, Kim, Delputte, Peter, Herschke, Florence
Published in Antiviral research (01.09.2024)
Published in Antiviral research (01.09.2024)
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