Total Synthesis of Norhalichondrin B
Jackson, Katrina L, Henderson, James A, Motoyoshi, Hajime, Phillips, Andrew J
Published in Angewandte Chemie (International ed.) (01.01.2009)
Published in Angewandte Chemie (International ed.) (01.01.2009)
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Journal Article
Synthesis and Structure of Two New Mycolactones Isolated from M. ulcerans subsp. shinshuense
Hande, Sudhir M, Kazumi, Yuko, Lai, W. George, Jackson, Katrina L, Maeda, Shinji, Kishi, Yoshito
Published in Organic letters (07.09.2012)
Published in Organic letters (07.09.2012)
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Journal Article
The Halichondrins and E7389
Jackson, Katrina L, Henderson, James A, Phillips, Andrew J
Published in Chemical reviews (01.07.2009)
Published in Chemical reviews (01.07.2009)
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Journal Article
Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1
Boyd, Michael J, Collier, Philip N, Clark, Michael P, Deng, Hongbo, Kesavan, Sarathy, Ronkin, Steven M, Waal, Nathan, Wang, Jian, Cao, Jingrong, Li, Pan, Come, Jon, Davies, Ioana, Duffy, John P, Cochran, John E, Court, John J, Chandupatla, Kishan, Jackson, Katrina L, Maltais, Francois, O’Dowd, Hardwin, Boucher, Christina, Considine, Tony, Taylor, William P, Gao, Hong, Chakilam, Ananthisrinivas, Engtrakul, Juntyma, Crawford, Dan, Doyle, Elizabeth, Phillips, Jonathan, Kemper, Raymond, Swett, Rebecca, Empfield, James, Bunnage, Mark E, Charifson, Paul S, Magavi, Sanjay Shivayogi
Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
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Journal Article
Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1
Come, Jon H, Senter, Timothy J, Clark, Michael P, Court, John J, Gale-Day, Zachary, Gu, Wenxin, Krueger, Elaine, Liang, Jianglin, Morris, Mark, Nanthakumar, Suganthini, O’Dowd, Hardwin, Maltais, Francois, Iyer, Ganesh, Andreassi, John, Boucher, Christina, Considine, Tony, Moody, Cameron S, Taylor, William, Mohanty, Arun K, Huang, Yulin, Zuccola, Harmon, Coll, Joyce, Bonanno, Kenneth C, Gagnon, Kevin J, Gan, Lu, Lu, Fan, Gao, Hong, Chakilam, Ananthisrinivas, Engtrakul, Juntyma, Song, Bin, Crawford, Dan, Doyle, Elisabeth, Kramer, Tal, Vought, Bryan, Phillips, Jonathan, Kemper, Raymond, Sanders, Martin, Swett, Rebecca, Furey, Brinley, Winquist, Ray, Bunnage, Mark E, Jackson, Katrina L, Charifson, Paul S, Magavi, Sanjay S
Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
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Journal Article
A synthesis of the C1–C15 domain of the halichondrins
Jackson, Katrina L., Henderson, James A., Morris, Jonathan C., Motoyoshi, Hajime, Phillips, Andrew J.
Published in Tetrahedron letters (01.04.2008)
Published in Tetrahedron letters (01.04.2008)
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Journal Article
Heterogeneity in the stereochemistry of mycolactones isolated from M. marinum: toxins produced by fresh vs. saltwater fish pathogens
Kim, Han-Je, Jackson, Katrina L, Kishi, Yoshito, Williamson, Heather R, Mosi, Lydia, Small, Pamela L C
Published in Chemical communications (Cambridge, England) (01.01.2009)
Published in Chemical communications (Cambridge, England) (01.01.2009)
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Journal Article
표적화 단백질의 분해를 위한 트리시클릭 이종이관능성 화합물
HENDERSON JAMES A, JACKSON KATRINA L, MOUSTAKIM MOSES, LIANG YANKE, ANDERSON COREY DON, GARZA VICTORIA, DUPLESSIS MARTIN, NASVESCHUK CHRISTOPHER G
Year of Publication 17.07.2023
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Year of Publication 17.07.2023
Patent
BRD9의 표적화된 분해를 위한 화합물
YAP JEREMY L, JACKSON KATRINA L, VEITS GESINE KERSTIN, MOUSTAKIM MOSES, ZEID RHAMY, YIN NING, NASVESCHUK CHRISTOPHER G
Year of Publication 19.12.2022
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Year of Publication 19.12.2022
Patent
돌연변이 BRAF의 분해를 위한 요법
JACKSON KATRINA L, VEITS GESINE KERSTIN, PETTAZZONI PIERGIORGIO FRANCESO TOMMASO, FITZGERALD MARK E, HEWING DAVID STEPHEN, HUNZIKER DANIEL, DOLENTE COSIMO, GARZA VICTORIA, WICHMANN JUERGEN, YU ROBERT T, DUPLESSIS MARTIN, O'SHEA MORGAN WELZEL, NASVESCHUK CHRISTOPHER G, KRUMMENACHER DANIELA, LIANG YANKE, GOOD ANDREW CHARLES
Year of Publication 13.02.2024
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Year of Publication 13.02.2024
Patent
BRAF 분해제
JACKSON KATRINA L, PETTAZZONI PIERGIORGIO FRANCESCO TOMMASO, VEITS GESINE KERSTIN, MOUSTAKIM MOSES, FITZGERALD MARK E, KUHN BERND, HUNZIKER DANIEL, DOLENTE COSIMO, GARZA VICTORIA, HEWINGS DAVID STEPHEN, WICHMANN JUERGEN, DUPLESSIS MARTIN, O'SHEA MORGAN WELZEL, YU ROBERT T, NASVESCHUK CHRISTOPHER G, RIEMER CLAUS, YAP JEREMY L, RICKLIN FABIENNE, LIANG YANKE, GOOD ANDREW CHARLES
Year of Publication 23.03.2023
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Year of Publication 23.03.2023
Patent
CFT8634, a Clinical Stage BRD9 Bi DAC™ Degrader, Is Active in a Subset of Multiple Myeloma Cell Line Models and Synergistic When Combined with Pomalidomide
Poling, Laura L, Cocozziello, David, He, Minsheng, Hurh, Eunju, Lobbardi, Riadh, Jackson, Katrina L, Fisher, Stewart L, Pollock, Roy M
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Abstract 6046: CFT8634, a BRD9 BiDAC™ degrader, is active in a subset of multiple myeloma cell line models and synergistic when combined with pomalidomide or dexamethasone
Poling, Laura L., Cocozziello, David, he, Minsng, Hurh, Eunju, Lobbardi, Riadh, Jackson, Katrina L., Fisher, Stewart L., Pollock, Roy M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract ND05: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers
Liang, Yanke, Sowa, Mathew E., Jackson, Katrina L., Simard, Jeffrey R., Kreger, Bridget, Li, Ping, Poling, Laura, Baddour, Joelle, Good, Andrew, Huang, Hongwei, Eron, Scott, Nasveschuk, Christopher G., Yu, Robert, Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan W., Veits, Gesine, Yap, Jeremy L., Moustakim, Moses, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe S., Deibler, Richard, Cole, Kyle S., Cocozziello, David, Rahman, Fazlur, Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Pollock, Roy M., Fisher, Stewart L.
Published in Cancer research (Chicago, Ill.) (29.05.2023)
Published in Cancer research (Chicago, Ill.) (29.05.2023)
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Journal Article
Abstract 3425: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers
Liang, Yanke, Sowa, Mathew E., Jackson, Katrina L., Simard, Jeffrey R., Kreger, Bridget, Li, Ping, Poling, Laura, Baddour, Joelle, Good, Andrew, Huang, Hongwei, Eron, Scott, Nasveschuk, Christopher G., Yu, Robert, Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan W., Veits, Gesine, Yap, Jeremy Y., Moustakim, Moses, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe S., Deibler, Richard, Cole, Kyle S., Cocozziello, David, Rahman, Fazlur, Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Pollock, Roy M., Fisher, Stewart L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 2158: Preclinical evaluation of CFT1946 as a selective degrader of mutant BRAF for the treatment of BRAF driven cancers
Sowa, Mathew E., Kreger, Bridget, Baddour, Joelle, Liang, Yanke, Simard, Jeffrey R., Poling, Laura, Li, Ping, Yu, Robert, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe Sahil, Deibler, Richard, Cole, Kyle S., Eron, Scott, Cocozziello, David, Rahman, Fazlur, Moustakim, Moses, Nasveschuk, Christopher G., Jackson, Katrina L., Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan, Veits, Gesine, Yap, Jeremy L., Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Fisher, Stewart L., Pollock, Roy M.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers
Jackson, Katrina L., Agafonov, Roman V., Carlson, Mark W., Chaturvedi, Prasoon, Cocozziello, David, Cole, Kyle, Deibler, Richard, Eron, Scott J., Good, Andrew, Hart, Ashley A., He, Minsheng, Henderson, Christina S., Huang, Hongwei, Isasa, Marta, Kirby, R. Jason, Lee, Linda, Mahler, Michelle, Moustakim, Moses, Nasveschuk, Christopher G., Palmer, Michael, Poling, Laura L., Pollock, Roy M., Schnaderbeck, Matthew, Spence, Stan, Veits, Gesine K., Yap, Jeremy L., Yin, Ning, Zeid, Rhamy, Crystal, Adam S., Phillips, Andrew J., Fisher, Stewart L.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article