Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography
PERUMAL, Meg, PILLAI, Radhakrishna G, BARTHEL, Henryk, LEYTON, Julius, LATIGO, John R, FORSTER, Martin, MITCHELL, Fraser, JACKMAN, Ann L, ABOAGYE, Eric O
Published in Cancer research (Chicago, Ill.) (01.09.2006)
Published in Cancer research (Chicago, Ill.) (01.09.2006)
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Thymidylate Synthase Expression in Advanced Colorectal Cancer Predicts for Response to Raltitrexed
FARRUGIA, David C, FORD, Hugo E. R, JACKMAN, Ann L, CUNNINGHAM, David, DANENBERG, Kathleen D, DANENBERG, Peter V, BRABENDER, Jan, MCVICAR, A. David, AHERNE, G. Wynne, HARDCASTLE, Anthea, MCCARTHY, Keith
Published in Clinical cancer research (01.02.2003)
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Published in Clinical cancer research (01.02.2003)
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Inhibition by Uridine but not Thymidine of p53-Dependent Intestinal Apoptosis Initiated by 5-fluorouracil: Evidence for the Involvement of RNA Perturbation
Pritchard, D. Mark, Alastair J. M. Watson, Potten, Christopher S., Jackman, Ann L., Hickman, John A.
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
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Design and Synthesis of Cyclopenta[g]quinazoline-Based Antifolates as Inhibitors of Thymidylate Synthase and Potential Antitumor Agents
Bavetsias, Vassilios, Marriott, Jonathan H, Melin, Camille, Kimbell, Rosemary, Matusiak, Zbigniew S, Boyle, F. Thomas, Jackman, Ann L
Published in Journal of medicinal chemistry (18.05.2000)
Published in Journal of medicinal chemistry (18.05.2000)
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Targeting the α-folate receptor with cyclopenta[ g]quinazoline-based inhibitors of thymidylate synthase
Henderson, Elisa A., Bavetsias, Vassilios, Theti, Davinder S., Wilson, Stuart C., Clauss, Rainer, Jackman, Ann L.
Published in Bioorganic & medicinal chemistry (15.07.2006)
Published in Bioorganic & medicinal chemistry (15.07.2006)
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Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models
Banerji, Udai, Sain, Nivedita, Sharp, Swee Y., Valenti, Melanie, Asad, Yasmin, Ruddle, Ruth, Raynaud, Florence, Walton, Michael, Eccles, Suzanne A., Judson, Ian, Jackman, Ann L., Workman, Paul
Published in Cancer chemotherapy and pharmacology (01.11.2018)
Published in Cancer chemotherapy and pharmacology (01.11.2018)
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Patterns of Elevation of Plasma 2′-Deoxyuridine, a Surrogate Marker of Thymidylate Synthase (TS) Inhibition, after Administration of Two Different Schedules of 5-Fluorouracil and the Specific TS Inhibitors Raltitrexed (Tomudex) and ZD9331
FORD, Hugo E. R, MITCHELL, Fraser, CUNNINGHAM, David, FARRUGIA, David C, HILL, Mark E, REES, Charlotte, CALVERT, A. Hilary, JUDSON, Ian R, JACKMAN, Ann L
Published in Clinical cancer research (01.01.2002)
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Published in Clinical cancer research (01.01.2002)
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A liquid chromatographic–tandem mass spectrometric method for the determination of two selective thymidylate synthase inhibitors, BGC945 and BGC638, in mouse plasma
Wood, Nadya, Gibbs, David D., Jackman, Ann L., Henley, Alan, Workman, Paul, Raynaud, Florence
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.09.2005)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.09.2005)
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Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT
Sain, Nivedita, Krishnan, Bhavani, Ormerod, Michael G, De Rienzo, Assunta, Liu, Wai M, Kaye, Stanley B, Workman, Paul, Jackman, Ann L
Published in Molecular cancer therapeutics (01.05.2006)
Published in Molecular cancer therapeutics (01.05.2006)
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BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to α-folate receptor-overexpressing tumors
GIBBS, David D, THETI, Davinder S, JACKMAN, Ann L, WOOD, Nadya, GREEN, Matthew, RAYNAUD, Florence, VALENTI, Melanie, FORSTER, Martin D, MITCHELL, Fraser, BAVETSIAS, Vassilios, HENDERSON, Elisa
Published in Cancer research (Chicago, Ill.) (15.12.2005)
Published in Cancer research (Chicago, Ill.) (15.12.2005)
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Antifolates targeted specifically to the folate receptor
Jackman, Ann L, Theti, Davinder S, Gibbs, David D
Published in Advanced drug delivery reviews (29.04.2004)
Published in Advanced drug delivery reviews (29.04.2004)
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Journal Article
Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945
Pillai, Radhakrishna G, Forster, Martin, Perumal, Meg, Mitchell, Fraser, Leyton, Julius, Aibgirhio, Franklin I, Golovko, Oksana, Jackman, Ann L, Aboagye, Eric O
Published in Cancer research (Chicago, Ill.) (15.05.2008)
Published in Cancer research (Chicago, Ill.) (15.05.2008)
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An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models
Banerji, Udai, Sain, Nivedita, Sharp, Swee Y., Valenti, Melanie, Asad, Yasmin, Ruddle, Ruth, Raynaud, Florence, Walton, Michael, Eccles, Suzanne A., Judson, Ian, Jackman, Ann L., Workman, Paul
Published in Cancer chemotherapy and pharmacology (01.10.2008)
Published in Cancer chemotherapy and pharmacology (01.10.2008)
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The Importance of p53-Independent Apoptosis in the Intestinal Toxicity Induced by Raltitrexed (ZD1694, Tomudex): Genetic Differences between BALB/c and DBA/2 Mice
PRITCHARD, D. Mark, BOWER, Lawrence, POTTEN, Christopher S, JACKMAN, Ann L, HICKMAN, John A
Published in Clinical cancer research (01.11.2000)
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Published in Clinical cancer research (01.11.2000)
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Flow cytometric method for determining folate receptor expression on ovarian carcinoma cells
Forster, Martin D, Ormerod, Michael G, Agarwal, Roshan, Kaye, Stanley B, Jackman, Ann L
Published in Cytometry. Part A (01.11.2007)
Published in Cytometry. Part A (01.11.2007)
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Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications
Marsham, Peter R, Hughes, Leslie R, Jackman, Ann L, Hayter, Anthony J, Oldfield, John, Wardleworth, J. Michael, Bishop, Joel A. M, O'Connor, Brigid M, Calvert, A. Hilary
Published in Journal of medicinal chemistry (01.05.1991)
Published in Journal of medicinal chemistry (01.05.1991)
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Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the α-isoform of the folate receptor
THETI, Davinder S, BAVETSIAS, Vassilios, SKELTON, Lorraine A, TITLEY, Jenny, GIBBS, David, JANSEN, Gerrit, JACKMAN, Ann L
Published in Cancer research (Chicago, Ill.) (01.07.2003)
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Published in Cancer research (Chicago, Ill.) (01.07.2003)
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