The Methylation Effect in Medicinal Chemistry
Barreiro, Eliezer J, Kümmerle, Arthur E, Fraga, Carlos A. M
Published in Chemical reviews (14.09.2011)
Published in Chemical reviews (14.09.2011)
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Recent Advances in Development of Polyphenols as Anticancer Agents
Thota, Sreekanth, Rodrigues, Daniel Alencar, Barreiro, Eliezer J
Published in Mini reviews in medicinal chemistry (01.01.2018)
Published in Mini reviews in medicinal chemistry (01.01.2018)
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Journal Article
Effect of S–Se Bioisosteric Exchange on Affinity and Intrinsic Efficacy of Novel N-acylhydrazone Derivatives at the Adenosine A2A Receptor
Pedreira, Júlia Galvez Bulhões, Silva, Rafaela Ribeiro, Noël, François G., Barreiro, Eliezer J.
Published in Molecules (Basel, Switzerland) (04.12.2021)
Published in Molecules (Basel, Switzerland) (04.12.2021)
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Chemical Intuition in Drug Design and Discovery
Pedreira, Julia Galvez B, Franco, Lucas S, Barreiro, Eliezer J
Published in Current topics in medicinal chemistry (01.01.2019)
Published in Current topics in medicinal chemistry (01.01.2019)
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The total synthesis of calcium atorvastatin
Dias, Luiz C., Vieira, Adriano S., Barreiro, Eliezer J.
Published in Organic & biomolecular chemistry (21.02.2016)
Published in Organic & biomolecular chemistry (21.02.2016)
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Characterization of amide bond conformers for a novel heterocyclic template of N-acylhydrazone derivatives
Lopes, Alexandra Basilio, Miguez, Eduardo, Kümmerle, Arthur Eugen, Rumjanek, Victor Marcos, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J
Published in Molecules (Basel, Switzerland) (25.09.2013)
Published in Molecules (Basel, Switzerland) (25.09.2013)
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The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease
da Rocha, Miguel Divino, Viegas, Flávia Pereira Dias, Campos, Helineide Cristina, Nicastro, Patrícia Carolina, Fossaluzza, Poliana Calve, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J, Viegas, Jr, Claudio
Published in CNS & neurological disorders drug targets (01.03.2011)
Published in CNS & neurological disorders drug targets (01.03.2011)
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Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors
Kümmerle, Arthur E, Schmitt, Martine, Cardozo, Suzana V. S, Lugnier, Claire, Villa, Pascal, Lopes, Alexandra B, Romeiro, Nelilma C, Justiniano, Hélène, Martins, Marco A, Fraga, Carlos A. M, Bourguignon, Jean-Jacques, Barreiro, Eliezer J
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile
Pillpe-Meza, Raysa Magali, Gouveia, Wesley Leandro, Barbosa, Gisele, Fraga, Carlos A M, Barreiro, Eliezer J, Lima, Lidia Moreira
Published in Pharmaceuticals (Basel, Switzerland) (01.03.2024)
Published in Pharmaceuticals (Basel, Switzerland) (01.03.2024)
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Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2- a]pyridine symbiotic prototypes
Lacerda, Renata B., de Lima, Cleverton K.F., da Silva, Leandro L., Romeiro, Nelilma C., Miranda, Ana Luisa P., Barreiro, Eliezer J., Fraga, Carlos A.M.
Published in Bioorganic & medicinal chemistry (2009)
Published in Bioorganic & medicinal chemistry (2009)
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Design and Synthesis In Silico Drug-like Prediction and Pharmacological Evaluation of Cyclopolymethylenic Homologous of LASSBio-1514
Lima, Lidia Moreira, da Silva, Tiago Fernandes, da Silva Monteiro, Carlos Eduardo, Aparecida-Silva, Cristiane, Bispo Júnior, Walfrido, de Queiroz, Aline Cavalcanti, Alexandre-Moreira, Magna Suzana, Zapata-Sudo, Gisele, Barreiro, Eliezer J
Published in Molecules (Basel, Switzerland) (10.08.2021)
Published in Molecules (Basel, Switzerland) (10.08.2021)
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Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues
do Amaral, Daniel Nascimento, Cavalcanti, Bruno C, Bezerra, Daniel P, Ferreira, Paulo Michel P, Castro, Rosane de Paula, Sabino, José Ricardo, Machado, Camila Maria Longo, Chammas, Roger, Pessoa, Claudia, Sant'Anna, Carlos M R, Barreiro, Eliezer J, Lima, Lídia Moreira
Published in PloS one (10.03.2014)
Published in PloS one (10.03.2014)
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Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
Thota, Sreekanth, Rodrigues, Daniel A, Crans, Debbie C, Barreiro, Eliezer J
Published in Journal of medicinal chemistry (26.07.2018)
Published in Journal of medicinal chemistry (26.07.2018)
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Comparative chemical and biological hydrolytic stability of homologous esters and isosteres
de Souza, Hygor M. R., Guedes, Jéssica S., Freitas, Rosana H. C. N., Gelves, Luis G. V., Fokoue, Harold H., Sant'Anna, Carlos Mauricio R., Barreiro, Eliezer J., Lima, Lidia M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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A novel scaffold for EGFR inhibition: Introducing N-(3-(3-phenylureido)quinoxalin-6-yl) acrylamide derivatives
do Amaral, Daniel Nascimento, Lategahn, Jonas, Fokoue, Harold Hilarion, da Silva, Eduardo Miguez Bastos, Sant’Anna, Carlos Mauricio R., Rauh, Daniel, Barreiro, Eliezer J., Laufer, Stefan, Lima, Lidia Moreira
Published in Scientific reports (09.01.2019)
Published in Scientific reports (09.01.2019)
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Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs
Barbosa, Gisele, Gelves, Luis Gabriel Valdivieso, Costa, Caroline Marques Xavier, Franco, Lucas Silva, Lima, João Alberto Lins de, Aparecida-Silva, Cristiane, Teixeira, John Douglas, Mermelstein, Claudia Dos Santos, Barreiro, Eliezer J, Lima, Lidia Moreira
Published in Pharmaceuticals (Basel, Switzerland) (23.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (23.07.2022)
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