Magnetic relaxation pathways in lanthanide single-molecule magnets
Blagg, Robin J., Ungur, Liviu, Tuna, Floriana, Speak, James, Comar, Priyanka, Collison, David, Wernsdorfer, Wolfgang, McInnes, Eric J. L., Chibotaru, Liviu F., Winpenny, Richard E. P.
Published in Nature chemistry (01.08.2013)
Published in Nature chemistry (01.08.2013)
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Journal Article
A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors
Zhou, Jia, Gelot, Camille, Pantelidou, Constantia, Li, Adam, Yücel, Hatice, Davis, Rachel E, Färkkilä, Anniina, Kochupurakkal, Bose, Syed, Aleem, Shapiro, Geoffrey I, Tainer, John A, Blagg, Brian S J, Ceccaldi, Raphael, D'Andrea, Alan D
Published in Nature cancer (01.06.2021)
Published in Nature cancer (01.06.2021)
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Journal Article
Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
Khandelwal, Anuj, Kent, Caitlin N., Balch, Maurie, Peng, Shuxia, Mishra, Sanket J., Deng, Junpeng, Day, Victor W., Liu, Weiya, Subramanian, Chitra, Cohen, Mark, Holzbeierlein, Jeffery M., Matts, Robert, Blagg, Brian S. J.
Published in Nature communications (30.01.2018)
Published in Nature communications (30.01.2018)
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Journal Article
JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells
Walters, Z S, Villarejo-Balcells, B, Olmos, D, Buist, T W S, Missiaglia, E, Allen, R, Al-Lazikani, B, Garrett, M D, Blagg, J, Shipley, J
Published in Oncogene (27.02.2014)
Published in Oncogene (27.02.2014)
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Journal Article
Hsp90 activator Aha1 drives production of pathological tau aggregates
Shelton, Lindsey B., Baker, Jeremy D., Zheng, Dali, Sullivan, Leia E., Solanki, Parth K., Webster, Jack M., Sun, Zheying, Sabbagh, Jonathan J., Nordhues, Bryce A., Koren, John, Ghosh, Suman, Blagg, Brian S. J., Blair, Laura J., Dickey, Chad A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.09.2017)
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Journal Article
Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents
Zhao, Huiping, Donnelly, Alison C, Kusuma, Bhaskar R, Brandt, Gary E. L, Brown, Douglas, Rajewski, Roger A, Vielhauer, George, Holzbeierlein, Jeffrey, Cohen, Mark S, Blagg, Brian S. J
Published in Journal of medicinal chemistry (09.06.2011)
Published in Journal of medicinal chemistry (09.06.2011)
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Journal Article
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding
Que, Nanette L. S, Crowley, Vincent M, Duerfeldt, Adam S, Zhao, Jinbo, Kent, Caitlin N, Blagg, Brian S. J, Gewirth, Daniel T
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Inhibiting spinal cord-specific hsp90 isoforms reveals a novel strategy to improve the therapeutic index of opioid treatment
Duron, David I., Tanguturi, Parthasaradhireddy, Campbell, Christopher S., Chou, Kerry, Bejarano, Paul, Gabriel, Katherin A., Bowden, Jessica L., Mishra, Sanket, Brackett, Christopher, Barlow, Deborah, Houseknecht, Karen L., Blagg, Brian S. J., Streicher, John M.
Published in Scientific reports (26.06.2024)
Published in Scientific reports (26.06.2024)
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Journal Article
Pentametallic lanthanide-alkoxide square-based pyramids: high energy barrier for thermal relaxation in a holmium single molecule magnet
Blagg, Robin J, Tuna, Floriana, McInnes, Eric J L, Winpenny, Richard E P
Published in Chemical communications (Cambridge, England) (01.01.2011)
Published in Chemical communications (Cambridge, England) (01.01.2011)
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Journal Article
Gambogic Acid, a Natural Product Inhibitor of Hsp90
Davenport, Jason, Manjarrez, Jacob R, Peterson, Laura, Krumm, Brian, Blagg, Brian S. J, Matts, Robert L
Published in Journal of natural products (Washington, D.C.) (27.05.2011)
Published in Journal of natural products (Washington, D.C.) (27.05.2011)
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Journal Article
Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations
Tomašič, Tihomir, Durcik, Martina, Keegan, Bradley M, Skledar, Darja Gramec, Zajec, Živa, Blagg, Brian S J, Bryant, Sharon D
Published in International journal of molecular sciences (20.09.2020)
Published in International journal of molecular sciences (20.09.2020)
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Journal Article
QSAR Studies to Predict Activity of HSP90 Inhibitors
Patil, Vaishali M, Masand, Neeraj, Gupta, Satya P, Blagg, Brian S J
Published in Current topics in medicinal chemistry (01.01.2021)
Published in Current topics in medicinal chemistry (01.01.2021)
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Journal Article
Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer
Charlestin, Verodia, Tan, Elijah, Arias-Matus, Carlos Eduardo, Wu, Junmin, Miranda-Vergara, Maria Cristina, Lee, Mijoon, Wang, Man, Nannapaneni, Dharma T, Tennakoon, Parinda, Blagg, Brian S J, Ashfeld, Brandon L, Kaliney, William, Li, Jun, Littlepage, Laurie E
Published in Cancers (01.08.2024)
Published in Cancers (01.08.2024)
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Journal Article
C-Terminal Heat Shock Protein 90 Inhibitor Decreases Hyperglycemia-induced Oxidative Stress and Improves Mitochondrial Bioenergetics in Sensory Neurons
Zhang, Liang, Zhao, Huiping, Blagg, Brian S. J, Dobrowsky, Rick T
Published in Journal of proteome research (06.04.2012)
Published in Journal of proteome research (06.04.2012)
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Journal Article
3-Arylcoumarin Derivatives Manifest Anti-proliferative Activity through Hsp90 Inhibition
Zhao, Huiping, Yan, Bin, Peterson, Laura B, Blagg, Brian S. J
Published in ACS medicinal chemistry letters (12.04.2012)
Published in ACS medicinal chemistry letters (12.04.2012)
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Journal Article
Novel C‐terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self‐renewal, and epithelial–mesenchymal transition
Subramanian, Chitra, Grogan, Patrick T., Wang, Ton, Bazzill, Joseph, Zuo, Ang, White, Peter T., Kalidindi, Avinaash, Kuszynski, Dawn, Wang, Grace, Blagg, Brian S. J., Cohen, Mark S.
Published in Molecular oncology (01.09.2020)
Published in Molecular oncology (01.09.2020)
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Journal Article
Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target
Pal, Ranu, Hui, Dongwei, Menchen, Heather, Zhao, Huiping, Mozziconacci, Olivier, Wilkins, Heather, Blagg, Brian S J, Schöneich, Christian, Swerdlow, Russell H, Michaelis, Mary L, Michaelis, Elias K
Published in Frontiers in aging neuroscience (14.11.2023)
Published in Frontiers in aging neuroscience (14.11.2023)
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Preliminary demonstration of benchtop NMR metabolic profiling of feline urine: chronic kidney disease as a case study
Finch, Natalie, Percival, Benita, Hunter, Elena, Blagg, Robin J, Blackwell, Emily, Sagar, James, Ahmad, Zeeshan, Chang, Ming-Wei, Hunt, John A, Mather, Melissa L, Tasker, Séverine, De Risio, Luisa, Wilson, Philippe B
Published in BMC research notes (24.12.2021)
Published in BMC research notes (24.12.2021)
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