Synthesis and pharmacological activity of SC-53228, a leukotriene B4 receptor antagonist with high intrinsic potency and selectivity
DJURIC, S. W, DOCTER, S. H, VILLANI-PRICE, D, RAO, T. S, WALSH, R. E, WIDOMSKI, D. L, FRETLAND, D. J, YU, S. S, SPANGLER, D, BIE-SHUNG TSAI, ANGLIN, C. P, GAGINELLA, T. S, KACHUR, J. F, KEITH, R. H, MAZIASZ, T. J
Published in Bioorganic & medicinal chemistry letters (24.03.1994)
Published in Bioorganic & medicinal chemistry letters (24.03.1994)
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Neurohumoral control of ileal electrolyte transport. I. Bombesin and related peptides
Kachur, J F, Miller, R J, Field, M, Rivier, J
Published in The Journal of pharmacology and experimental therapeutics (01.03.1982)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1982)
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Neuromodulation of guinea pig intestinal electrolyte transport by cholecystokinin octapeptide
Kachur, J F, Phillips, G S, Gaginella, T S
Published in Gastroenterology (New York, N.Y. 1943) (01.02.1991)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.1991)
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Synthesis and pharmacological activity of rationally designed inhibitors of the leukotriene A4 hydrolase enzyme
Djuric, Stevan W., Huff, Renee M., Penning, Thomas D., Clare, Michael, Swenton, Lydia, Kachur, James F., Villani-Price, Doreen, Krivi, Gwen G., Pyla, E.Yvonne, Warren, Thomas G.
Published in Bioorganic & medicinal chemistry letters (01.11.1992)
Published in Bioorganic & medicinal chemistry letters (01.11.1992)
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In vitro effects of somatostatin on ion transport in rabbit intestine
Guandalini, S, Kachur, J F, Smith, P L, Miller, R J, Field, M
Published in The American journal of physiology (01.02.1980)
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Published in The American journal of physiology (01.02.1980)
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Peptides in the control of gastrointestinal function
Miller, R J, Kachur, J F, Smith, P L, Guandalini, S, Field, M
Published in Society of General Physiologists series (1980)
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Published in Society of General Physiologists series (1980)
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Synthesis and pharmacologic properties of 6-succinylcodeine
Toro-Goyco, E, Zenk, P C, Estrada, U, Kachur, J F, Harris, L S
Published in Pharmacological research communications (01.08.1987)
Published in Pharmacological research communications (01.08.1987)
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Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase I: in vitro studies
Askonas, Leslie J, Kachur, James F, Villani-Price, Doreen, Liang, Chi-Dean D, Russell, Mark A, Smith, Walter G
Published in The Journal of pharmacology and experimental therapeutics (01.02.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2002)
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Synthesis of potent leukotriene A(4) hydrolase inhibitors. identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid
Penning, TD, Russell, MA, Chen, BB, Chen, HY, Liang, CD, Mahoney, MW, Malecha, JW, Miyashiro, JM, Yu, SS, Askonas, LJ, Gierse, JK, Harding, EI, Highkin, MK, Kachur, JF, Kim, SH, Villani-Price, D, Pyla, EY, Ghoreishi-Haack, NS, Smith, WG
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Journal Article
Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies
Kachur, James F, Askonas, Leslie J, Villani-Price, Doreen, Ghoreishi-Haack, Nayereh, Won-Kim, Suzanne, Liang, Chi-Dean D, Russell, Mark A, Smith, Walter G
Published in The Journal of pharmacology and experimental therapeutics (01.02.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2002)
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Ca-mediated stimulation of CI secretion by reactive oxygen metabolites in human colonic T84 cells
Tamai, H, Gaginella, T S, Kachur, J F, Musch, M W, Chang, E B
Published in The Journal of clinical investigation (01.01.1992)
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Published in The Journal of clinical investigation (01.01.1992)
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Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase
Penning, Thomas D, Chandrakumar, Nizal S, Desai, Bipin N, Djuric, Stevan W, Gasiecki, Alan F, Liang, Chi-Dean, Miyashiro, Julie M, Russell, Mark A, Askonas, Leslie J, Gierse, James K, Harding, Elizabeth I, Highkin, Maureen K, Kachur, James F, Kim, Suzanne H, Villani-Price, Doreen, Pyla, E Yvonne, Ghoreishi-Haack, Nayereh S, Smith, Walter G
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
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Regulation of guinea pig ileal electrolyte transport by M sub(3)-muscarinic acetylcholine receptors in vitro
Kachur, J F, Sturm, B L, Gaginella, T S, Noronha-Blob, L
Published in Molecular pharmacology (01.01.1990)
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Published in Molecular pharmacology (01.01.1990)
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In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues
Noronha-Blob, L, Sturm, B L, Lowe, V C, Jackson, K N, Kachur, J F
Published in Life sciences (1973) (1990)
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Published in Life sciences (1973) (1990)
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Multiple actions of the leukotriene B sub(4) receptor antagonist SC-41930
Villani-Price, D, Yang, D C, Walsh, R E, Fretland, D J, Keith, R H, Kocan, G, Kachur, J F, Gaginella, T S, Tsai, B S
Published in The Journal of pharmacology and experimental therapeutics (01.01.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1992)
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