Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging
Hou, Ying-Chen Claire, Yu, Hung-Chun, Martin, Rick, Cirulli, Elizabeth T., Schenker-Ahmed, Natalie M., Hicks, Michael, Cohen, Isaac V., Jönsson, Thomas J., Heister, Robyn, Napier, Lori, Swisher, Christine Leon, Dominguez, Saints, Tang, Haibao, Li, Weizhong, Perkins, Bradley A., Barea, Jaime, Rybak, Christina, Smith, Emily, Duchicela, Keegan, Doney, Michael, Brar, Pamila, Hernandez, Nathaniel, Kirkness, Ewen F., Kahn, Andrew M., Venter, J. Craig, Karow, David S., Caskey, C. Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2020)
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Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults
Perkins, Bradley A., Caskey, C. Thomas, Brar, Pamila, Dec, Eric, Karow, David S., Kahn, Andrew M., Hou, Ying-Chen Claire, Shah, Naisha, Boeldt, Debbie, Coughlin, Erin, Hands, Gabby, Lavrenko, Victor, Yu, James, Procko, Andrea, Appis, Julia, Dale, Anders M., Guo, Lining, Jönsson, Thomas J., Wittmann, Bryan M., Bartha, Istvan, Ramakrishnan, Smriti, Bernal, Axel, Brewer, James B., Brewerton, Suzanne, Biggs, William H., Turpaz, Yaron, Venter, J. Craig
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
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Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery
Phalen, Timothy J, Weirather, Kelly, Deming, Paula B, Anathy, Vikas, Howe, Alan K, van der Vliet, Albert, Jönsson, Thomas J, Poole, Leslie B, Heintz, Nicholas H
Published in The Journal of cell biology (04.12.2006)
Published in The Journal of cell biology (04.12.2006)
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Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
Summitt, Candice B, Johnson, Lynnette C, Jönsson, Thomas J, Parsonage, Derek, Holmes, Ross P, Lowther, W Todd
Published in Biochemical journal (01.03.2015)
Published in Biochemical journal (01.03.2015)
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Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins
Cox, Andrew G, Pearson, Andree G, Pullar, Juliet M, Jönsson, Thomas J, Lowther, W Todd, Winterbourn, Christine C, Hampton, Mark B
Published in Biochemical journal (12.06.2009)
Published in Biochemical journal (12.06.2009)
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Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State
Forshaw, Tom E, Reisz, Julie A, Nelson, Kimberly J, Gumpena, Rajesh, Lawson, J Reed, Jönsson, Thomas J, Wu, Hanzhi, Clodfelter, Jill E, Johnson, Lynnette C, Furdui, Cristina M, Lowther, W Todd
Published in Antioxidants (11.06.2021)
Published in Antioxidants (11.06.2021)
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Identification of Intact Protein Thiosulfinate Intermediate in the Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Human Sulfiredoxin
Jönsson, Thomas J., Tsang, Allen W., Lowther, W. Todd, Furdui, Cristina M.
Published in The Journal of biological chemistry (22.08.2008)
Published in The Journal of biological chemistry (22.08.2008)
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Metabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in rats
Fujieda, Yusuke, Ueno, Shinya, Ogino, Ryoko, Kuroda, Mariko, Jönsson, Thomas J, Guo, Lining, Bamba, Takeshi, Fukusaki, Eiichiro
Published in PloS one (13.08.2012)
Published in PloS one (13.08.2012)
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The Thioredoxin Domain of Neisseria gonorrhoeae PilB Can Use Electrons from DsbD to Reduce Downstream Methionine Sulfoxide Reductases
Brot, Nathan, Collet, Jean-François, Johnson, Lynnette C., Jönsson, Thomas J., Weissbach, Herbert, Lowther, W. Todd
Published in The Journal of biological chemistry (27.10.2006)
Published in The Journal of biological chemistry (27.10.2006)
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Cognitive enhancement in old dogs from dietary supplementation with a nutrient blend containing arginine, antioxidants, B vitamins and fish oil
Pan, Yuanlong, Kennedy, Adam D., Jönsson, Thomas J., Milgram, Nortan W.
Published in British journal of nutrition (14.02.2018)
Published in British journal of nutrition (14.02.2018)
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A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone
Jönsson, Thomas J, Schäfer, Hans-Ludwig, Herling, Andreas W, Brönstrup, Mark
Published in PloS one (27.11.2018)
Published in PloS one (27.11.2018)
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Protein Engineering of the Quaternary Sulfiredoxin·Peroxiredoxin Enzyme·Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation
Jönsson, Thomas J., Johnson, Lynnette C., Lowther, W.Todd
Published in The Journal of biological chemistry (27.11.2009)
Published in The Journal of biological chemistry (27.11.2009)
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Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Sulfiredoxin Proceeds Directly through a Sulfinic Phosphoryl Ester Intermediate
Jönsson, Thomas J., Murray, Michael S., Johnson, Lynnette C., Lowther, W. Todd
Published in The Journal of biological chemistry (29.08.2008)
Published in The Journal of biological chemistry (29.08.2008)
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Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones
Cohen, Isaac V., Cirulli, Elizabeth T., Mitchell, Matthew W., Jonsson, Thomas J., Yu, James, Shah, Naisha, Spector, Tim D., Guo, Lining, Venter, J. Craig, Telenti, Amalio
Published in EBioMedicine (01.02.2018)
Published in EBioMedicine (01.02.2018)
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Mutant AhpC Peroxiredoxins Suppress Thiol-Disulfide Redox Deficiencies and Acquire Deglutathionylating Activity
Yamamoto, Yuji, Ritz, Dani, Planson, Anne-Gaëlle, Jönsson, Thomas J., Faulkner, Melinda J., Boyd, Dana, Beckwith, Jon, Poole, Leslie B.
Published in Molecular cell (18.01.2008)
Published in Molecular cell (18.01.2008)
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