Microfluidic-Assisted Engineering of Quasi-Monodisperse pH-Responsive Polymersomes toward Advanced Platforms for the Intracellular Delivery of Hydrophilic Therapeutics
Albuquerque, Lindomar J. C, Sincari, Vladimir, Jäger, Alessandro, Konefał, Rafal, Pánek, Jiří, Černoch, Peter, Pavlova, Ewa, Štěpánek, Petr, Giacomelli, Fernando C, Jäger, Eliézer
Published in Langmuir (25.06.2019)
Published in Langmuir (25.06.2019)
Get full text
Journal Article
Reactive Oxygen Species (ROS)-Responsive Polymersomes with Site-Specific Chemotherapeutic Delivery into Tumors via Spacer Design Chemistry
Jäger, Eliézer, Sincari, Vladimir, Albuquerque, Lindomar J. C, Jäger, Alessandro, Humajova, Jana, Kucka, Jan, Pankrac, Jan, Paral, Petr, Heizer, Tomas, Janouskova, Olga, Konefał, Rafał, Pavlova, Ewa, Sedlacek, Ondrej, Giacomelli, Fernando C, Pouckova, Pavla, Sefc, Ludek, Stepanek, Petr, Hruby, Martin
Published in Biomacromolecules (13.04.2020)
Published in Biomacromolecules (13.04.2020)
Get full text
Journal Article
pH and ROS Responsiveness of Polymersome Nanovaccines for Antigen and Adjuvant Codelivery: An In Vitro and In Vivo Comparison
Jäger, Eliézer, Ilina, Olga, Dölen, Yusuf, Valente, Michael, van Dinther, Eric A.W., Jäger, Alessandro, Figdor, Carl G., Verdoes, Martijn
Published in Biomacromolecules (11.03.2024)
Published in Biomacromolecules (11.03.2024)
Get full text
Journal Article
Role of Membrane Features on the Permeability Behavior of Polymersomes and the Potential Impacts on Drug Encapsulation and Release
de Oliveira, Fernando A., Batista, Carin Cristina da Silva, Černoch, Peter, Sincari, Vladimir, Jäger, Alessandro, Jäger, Eliézer, Giacomelli, Fernando C.
Published in Biomacromolecules (08.05.2023)
Published in Biomacromolecules (08.05.2023)
Get full text
Journal Article
Membrane Permeability and Responsiveness Drive Performance: Linking Structural Features with the Antitumor Effectiveness of Doxorubicin-Loaded Stimuli-Triggered Polymersomes
Jäger, Eliézer, Černoch, Peter, Vragovic, Martina, Calumby Albuquerque, Lindomar Jose, Sincari, Vladimir, Heizer, Tomáš, Jäger, Alessandro, Kučka, Jan, Janoušková, Olga Šebestová, Pavlova, Ewa, Šefc, Luděk, Giacomelli, Fernando Carlos
Published in Biomacromolecules (08.07.2024)
Published in Biomacromolecules (08.07.2024)
Get full text
Journal Article
Probing the inner structure and dynamics of pH-sensitive block copolymer nanoparticles with nitroxide radicals using scattering and EPR techniques
Lukáš Petrova, Svetlana, Jäger, Alessandro, Pavlova, Ewa, Vragović, Martina, Jäger, Eliézer, Steinhart, Miloš, Klepac, Damir
Published in European polymer journal (15.11.2024)
Published in European polymer journal (15.11.2024)
Get full text
Journal Article
pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects
Albuquerque, Lindomar J.C., Sincari, Vladimir, Jäger, Alessandro, Kucka, Jan, Humajova, Jana, Pankrac, Jan, Paral, Petr, Heizer, Tomas, Janouškova, Olga, Davidovich, Irina, Talmon, Yeshayahu, Pouckova, Pavla, Štěpánek, Petr, Sefc, Ludek, Hruby, Martin, Giacomelli, Fernando C., Jäger, Eliézer
Published in Journal of controlled release (10.04.2021)
Published in Journal of controlled release (10.04.2021)
Get full text
Journal Article
Nanoparticle–Cell Interactions: Surface Chemistry Effects on the Cellular Uptake of Biocompatible Block Copolymer Assemblies
de Castro, Carlos E, Ribeiro, Caroline A. S, Alavarse, Alex C, Albuquerque, Lindomar J. C, da Silva, Maria C. C, Jäger, Eliézer, Surman, František, Schmidt, Vanessa, Giacomelli, Cristiano, Giacomelli, Fernando C
Published in Langmuir (06.02.2018)
Published in Langmuir (06.02.2018)
Get full text
Journal Article
pH-induced morphological reversible transition from microparticles to vesicles for effective bacteria entrapment
Sincari, Vladimir, Lukáš Petrova, Svetlana, Jäger, Eliézer, Jäger, Alessandro, Konefał, Rafał, Gajdošová, Veronika, Šlouf, Miroslav, Michaela, Hympánová, Marek, Jan, Soukup, Ondrej, Hrubý, Martin
Published in European polymer journal (11.12.2024)
Published in European polymer journal (11.12.2024)
Get full text
Journal Article
Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses
Dölen, Yusuf, Valente, Michael, Tagit, Oya, Jäger, Eliezer, Van Dinther, Eric A. W., van Riessen, N. Koen, Hruby, Martin, Gileadi, Uzi, Cerundolo, Vincenzo, Figdor, Carl G.
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
Get full text
Journal Article
Endolysosomal‐Escape Nanovaccines through Adjuvant‐Induced Tumor Antigen Assembly for Enhanced Effector CD8+ T Cell Activation
Qiu, Liping, Valente, Michael, Dolen, Yusuf, Jäger, Eliezer, Beest, Martin ter, Zheng, Liyan, Figdor, Carl G., Verdoes, Martijn
Published in Small (Weinheim an der Bergstrasse, Germany) (01.04.2018)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.04.2018)
Get full text
Journal Article
Outstanding protein-repellent feature of soft nanoparticles based on poly(N-(2-hydroxypropyl) methacrylamide) outer shells
de Oliveira, Fernando A., Albuquerque, Lindomar J.C., Riske, Karin A., Jäger, Eliézer, Giacomelli, Fernando C.
Published in Journal of colloid and interface science (15.08.2020)
Published in Journal of colloid and interface science (15.08.2020)
Get full text
Journal Article
Proteome changes of plasma-derived extracellular vesicles in patients with myelodysplastic syndrome
Pecankova, Klara, Pecherkova, Pavla, Gasova, Zdenka, Sovova, Zofie, Riedel, Tomas, Jäger, Eliézer, Cermak, Jaroslav, Majek, Pavel
Published in PloS one (10.01.2022)
Published in PloS one (10.01.2022)
Get full text
Journal Article
PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses
Dölen, Yusuf, Gileadi, Uzi, Chen, Ji-Li, Valente, Michael, Creemers, Jeroen H A, Van Dinther, Eric A W, van Riessen, N Koen, Jäger, Eliezer, Hruby, Martin, Cerundolo, Vincenzo, Diken, Mustafa, Figdor, Carl G, de Vries, I Jolanda M
Published in Frontiers in immunology (25.02.2021)
Published in Frontiers in immunology (25.02.2021)
Get full text
Journal Article
Poly(ethylene oxide monomethyl ether)-block-poly(propylene succinate) Nanoparticles: Synthesis and Characterization, Enzymatic and Cellular Degradation, Micellar Solubilization of Paclitaxel, and in Vitro and in Vivo Evaluation
Jäger, Alessandro, Jäger, Eliézer, Syrová, Zdeňka, Mazel, Tomas, Kováčik, Lubomír, Raška, Ivan, Höcherl, Anita, Kučka, Jan, Konefal, Rafal, Humajova, Jana, Poučková, Pavla, Štěpánek, Petr, Hrubý, Martin
Published in Biomacromolecules (09.07.2018)
Published in Biomacromolecules (09.07.2018)
Get full text
Journal Article
Smart Poly(lactide)- b -poly(triethylene glycol methyl ether methacrylate) (PLA- b -PTEGMA) Block Copolymers: One-Pot Synthesis, Temperature Behavior, and Controlled Release of Paclitaxel
Lukáš Petrova, Svetlana, Vragović, Martina, Pavlova, Ewa, Černochová, Zulfiya, Jäger, Alessandro, Jäger, Eliézer, Konefał, Rafał
Published in Pharmaceutics (08.04.2023)
Published in Pharmaceutics (08.04.2023)
Get full text
Journal Article
pH-Dependent disruption of giant polymer vesicles: a step towards biomimetic membranes
Sincari, Vladimir, Jäger, Eliézer, Loureiro, Kahynna Cavalcante, Vragovic, Martina, Hofmann, Eddie, Schlenk, Mathias, Filipová, Marcela, Rydvalová, Eliška, Št pánek, Petr, Hrubý, Martin, Förster, Stephan, Jäger, Alessandro
Published in Polymer chemistry (24.01.2023)
Published in Polymer chemistry (24.01.2023)
Get full text
Journal Article
Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation
Operti, Maria Camilla, Bernhardt, Alexander, Sincari, Vladimir, Jager, Eliezer, Grimm, Silko, Engel, Andrea, Hruby, Martin, Figdor, Carl Gustav, Tagit, Oya
Published in Pharmaceutics (25.01.2022)
Published in Pharmaceutics (25.01.2022)
Get full text
Journal Article