Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
Glaser, Stefan P, Lee, Erinna F, Trounson, Evelyn, Bouillet, Philippe, Wei, Andrew, Fairlie, W Douglas, Izon, David J, Zuber, Johannes, Rappaport, Amy R, Herold, Marco J, Alexander, Warren S, Lowe, Scott W, Robb, Lorraine, Strasser, Andreas
Published in Genes & development (15.01.2012)
Published in Genes & development (15.01.2012)
Get full text
Journal Article
Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment
Singbrant, Sofie, Russell, Megan R., Jovic, Tanja, Liddicoat, Brian, Izon, David J., Purton, Louise E., Sims, Natalie A., Martin, T. John, Sankaran, Vijay G., Walkley, Carl R.
Published in Blood (26.05.2011)
Published in Blood (26.05.2011)
Get full text
Journal Article
Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma
Smeets, Monique F M A, Chan, Angela C, Dagger, Samantha, Bradley, Cara K, Wei, Andrew, Izon, David J
Published in PloS one (07.05.2013)
Published in PloS one (07.05.2013)
Get full text
Journal Article
The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim
Jurado, Sabine, Gleeson, Kimberly, O'Donnell, Kristy, Izon, David J, Walkley, Carl R, Strasser, Andreas, Tarlinton, David M, Heierhorst, Jörg
Published in The Journal of experimental medicine (27.08.2012)
Published in The Journal of experimental medicine (27.08.2012)
Get full text
Journal Article
The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis
Smeets, Monique F, DeLuca, Elisabetta, Wall, Meaghan, Quach, Julie M, Chalk, Alistair M, Deans, Andrew J, Heierhorst, Jörg, Purton, Louise E, Izon, David J, Walkley, Carl R
Published in The Journal of clinical investigation (01.08.2014)
Published in The Journal of clinical investigation (01.08.2014)
Get full text
Journal Article
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms
Oliaro, Jane, Van Ham, Vanessa, Sacirbegovic, Faruk, Pasam, Anupama, Bomzon, Ze'ev, Pham, Kim, Ludford-Menting, Mandy J, Waterhouse, Nigel J, Bots, Michael, Hawkins, Edwin D, Watt, Sally V, Cluse, Leonie A, Clarke, Chris J P, Izon, David J, Chang, John T, Thompson, Natalie, Gu, Min, Johnstone, Ricky W, Smyth, Mark J, Humbert, Patrick O, Reiner, Steven L, Russell, Sarah M
Published in The Journal of immunology (1950) (01.07.2010)
Published in The Journal of immunology (1950) (01.07.2010)
Get full text
Journal Article
ATM Substrate Chk2-interacting Zn2+ Finger (ASCIZ) Is a Bi-functional Transcriptional Activator and Feedback Sensor in the Regulation of Dynein Light Chain (DYNLL1) Expression
Jurado, Sabine, Conlan, Lindus A., Baker, Emma K., Ng, Jane-Lee, Tenis, Nora, Hoch, Nicolas C., Gleeson, Kimberly, Smeets, Monique, Izon, David, Heierhorst, Jörg
Published in The Journal of biological chemistry (27.01.2012)
Published in The Journal of biological chemistry (27.01.2012)
Get full text
Journal Article
In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis
Göthert, Joachim R., Gustin, Sonja E., Hall, Mark A., Green, Anthony R., Göttgens, Berthold, Izon, David J., Begley, C.Glenn
Published in Blood (01.04.2005)
Published in Blood (01.04.2005)
Get full text
Journal Article
Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium
Göthert, Joachim R., Gustin, Sonja E., van Eekelen, J. Anke M., Schmidt, Uli, Hall, Mark A., Jane, Stephen M., Green, Anthony R., Göttgens, Berthold, Izon, David J., Begley, C. Glenn
Published in Blood (15.09.2004)
Published in Blood (15.09.2004)
Get full text
Journal Article
Removal of myeloid cytokines from the cellular environment enhances T-cell development in vitro
Smeets, Monique F M A, Mackenzie-Kludas, Charley, Mohtashami, Mahmood, Zhang, Hui-Hua, Zúñiga-Pflücker, Juan Carlos, Izon, David J
Published in International immunology (01.10.2013)
Published in International immunology (01.10.2013)
Get full text
Journal Article
The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7
Miller, Juli P, Izon, David, DeMuth, William, Gerstein, Rachel, Bhandoola, Avinash, Allman, David
Published in The Journal of experimental medicine (02.09.2002)
Published in The Journal of experimental medicine (02.09.2002)
Get full text
Journal Article
Deltex1 Redirects Lymphoid Progenitors to the B Cell Lineage by Antagonizing Notch1
Izon, David J, Aster, Jon C, He, Yiping, Weng, Andrew, Karnell, Fredrick G, Patriub, Vytas, Xu, Lanwei, Bakkour, Sonia, Rodriguez, Carlos, Allman, David, Pear, Warren S
Published in Immunity (Cambridge, Mass.) (01.02.2002)
Published in Immunity (Cambridge, Mass.) (01.02.2002)
Get full text
Journal Article
Constitutive Notch signalling promotes CD4−CD8− thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals
Michie, Alison M., Chan, Angela C., Ciofani, Maria, Carleton, Michael, Lefebvre, Juliette M., He, Yiping, Allman, David M., Wiest, David L., Zúñiga-Pflücker, Juan Carlos, Izon, David J.
Published in International immunology (01.12.2007)
Published in International immunology (01.12.2007)
Get full text
Journal Article
An Invitation to T and More: Notch Signaling in Lymphopoiesis
Allman, David, Punt, Jennifer A, Izon, David J, Aster, Jon C, Pear, Warren S
Published in Cell (01.04.2002)
Published in Cell (01.04.2002)
Get full text
Book Review
Journal Article
A method for prolonged imaging of motile lymphocytes
Day, Daniel, Pham, Kim, Ludford‐Menting, Mandy J, Oliaro, Jane, Izon, David, Russell, Sarah M, Gu, Min
Published in Immunology and cell biology (01.02.2009)
Published in Immunology and cell biology (01.02.2009)
Get full text
Journal Article
NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis
Göthert, Joachim R., Brake, Rachael L., Smeets, Monique, Dührsen, Ulrich, Begley, C. Glenn, Izon, David J.
Published in Blood (15.11.2007)
Published in Blood (15.11.2007)
Get full text
Journal Article
Overexpression of stem cell associated ALDH1A1 , a target of the leukemogenic transcription factor TLX1/HOX11, inhibits lymphopoiesis and promotes myelopoiesis in murine hematopoietic progenitors
Rice, Kim L, Izon, David J, Ford, Jette, Boodhoo, Alvin, Kees, Ursula R, Greene, Wayne K
Published in Leukemia research (01.06.2008)
Published in Leukemia research (01.06.2008)
Get full text
Journal Article