Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity
Iyamu, Iredia D., Zhao, Yingzhao, Parvatkar, Prakash T., Roberts, Bracken F., Casandra, Debora R., Wojtas, Lukasz, Kyle, Dennis E., Chakrabarti, Debopam, Manetsch, Roman
Published in Bioorganic & medicinal chemistry (01.03.2022)
Published in Bioorganic & medicinal chemistry (01.03.2022)
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Journal Article
A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes
Iyamu, Iredia D, Al-Hamashi, Ayad A, Huang, Rong
Published in Biomolecules (Basel, Switzerland) (08.06.2021)
Published in Biomolecules (Basel, Switzerland) (08.06.2021)
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Journal Article
Structure–Activity Relationship Studies on Cell-Potent Nicotinamide N‑Methyltransferase Bisubstrate Inhibitors
Iyamu, Iredia D., Zhao, Tianqi, Huang, Rong
Published in Journal of medicinal chemistry (10.08.2023)
Published in Journal of medicinal chemistry (10.08.2023)
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Journal Article
Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages
Roberts, Bracken F., Iyamu, Iredia D., Lee, Sukjun, Lee, Eunyoung, Ayong, Lawrence, Kyle, Dennis E., Yuan, Yu, Manetsch, Roman, Chakrabarti, Debopam
Published in International journal for parasitology -- drugs and drug resistance (01.04.2016)
Published in International journal for parasitology -- drugs and drug resistance (01.04.2016)
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Journal Article
Nicotinamide N-methyltransferase upregulation contributes to palmitate-elicited peroxisome proliferator-activated receptor transactivation in hepatocytes
Song, Qing, Wang, Jun, Griffiths, Alexandra, Lee, Samuel Man, Iyamu, Iredia D, Huang, Rong, Cordoba-Chacon, Jose, Song, Zhenyuan
Published in American Journal of Physiology: Cell Physiology (01.07.2023)
Published in American Journal of Physiology: Cell Physiology (01.07.2023)
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Journal Article
Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes
Griffiths, Alexandra, Wang, Jun, Song, Qing, Iyamu, Iredia D., Liu, Lifeng, Park, Jooman, Jiang, Yuwei, Huang, Rong, Song, Zhenyuan
Published in American Journal of Physiology: Cell Physiology (01.09.2021)
Published in American Journal of Physiology: Cell Physiology (01.09.2021)
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Journal Article
Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity
Meng, Ying, Iyamu, Iredia D., Ahmed, Noha A. M., Huang, Rong
Published in ACS chemical biology (19.01.2024)
Published in ACS chemical biology (19.01.2024)
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Journal Article
Effects of Small Molecule Ligands on ACKR3 Receptors
Hopkins, Brittany E., Masuho, Ikuo, Ren, Dongjun, Iyamu, Iredia D., Lv, Wei, Malik, Neha, Martemyanov, Kirill A., Schiltz, Gary E., Miller, Richard J.
Published in Molecular pharmacology (01.09.2022)
Published in Molecular pharmacology (01.09.2022)
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Journal Article
Going beyond Binary: Rapid Identification of Protein–Protein Interaction Modulators Using a Multifragment Kinetic Target-Guided Synthesis Approach
Nacheva, Katya, Kulkarni, Sameer S., Kassu, Mintesinot, Flanigan, David, Monastyrskyi, Andrii, Iyamu, Iredia D., Doi, Kenichiro, Barber, Megan, Namelikonda, Niranjan, Tipton, Jeremiah D., Parvatkar, Prakash, Wang, Hong-Gang, Manetsch, Roman
Published in Journal of medicinal chemistry (13.04.2023)
Published in Journal of medicinal chemistry (13.04.2023)
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Journal Article
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase
Zhou, Jujun, Deng, Youchao, Iyamu, Iredia D., Horton, John R., Yu, Dan, Hajian, Taraneh, Vedadi, Masoud, Rotili, Dante, Mai, Antonello, Blumenthal, Robert M., Zhang, Xing, Huang, Rong, Cheng, Xiaodong
Published in ACS chemical biology (21.04.2023)
Published in ACS chemical biology (21.04.2023)
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Journal Article
Synthesis of a novel fused pyrrolodiazepine-based library with anti-cancer activity
Malik, Neha, Iyamu, Iredia D., Scheidt, Karl A., Schiltz, Gary E.
Published in Tetrahedron letters (11.04.2018)
Published in Tetrahedron letters (11.04.2018)
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Journal Article
Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons
Han, Ye, Iyamu, Iredia D., Clutter, Matthew R., Mishra, Rama K., Lyman, Kyle A., Zhou, Chengwen, Michailidis, Ioannis, Xia, Maya Y., Sharma, Horrick, Luan, Chi-Hao, Schiltz, Gary E., Chetkovich, Dane M.
Published in The Journal of biological chemistry (01.07.2022)
Published in The Journal of biological chemistry (01.07.2022)
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Journal Article
Development of Tetrahydroindazole‐Based Potent and Selective Sigma‐2 Receptor Ligands
Iyamu, Iredia D., Lv, Wei, Malik, Neha, Mishra, Rama K., Schiltz, Gary E.
Published in ChemMedChem (03.07.2019)
Published in ChemMedChem (03.07.2019)
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Journal Article