Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
Bhattacharya, Akash, Alam, Steven L., Fricke, Thomas, Zadrozny, Kaneil, Sedzicki, Jaroslaw, Taylor, Alexander B., Demeler, Borries, Pornillos, Owen, Ganser-Pornillos, Barbie K., Diaz-Griffero, Felipe, Ivanov, Dmitri N., Yeager, Mark
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
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Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification
Yu, Corey H, Bhattacharya, Akash, Persaud, Mirjana, Taylor, Alexander B, Wang, Zhonghua, Bulnes-Ramos, Angel, Xu, Joella, Selyutina, Anastasia, Martinez-Lopez, Alicia, Cano, Kristin, Demeler, Borries, Kim, Baek, Hardies, Stephen C, Diaz-Griffero, Felipe, Ivanov, Dmitri N
Published in Nature communications (02.02.2021)
Published in Nature communications (02.02.2021)
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Structural and functional asymmetry of RING trimerization controls priming and extension events in TRIM5α autoubiquitylation
Herkules, Frank, Yu, Corey H, Taylor, Alexander B, Dougherty, Vi, Weintraub, Susan T, Ivanov, Dmitri N
Published in Nature communications (19.11.2022)
Published in Nature communications (19.11.2022)
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RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin
Yudina, Zinaida, Roa, Amanda, Johnson, Rory, Biris, Nikolaos, de Souza Aranha Vieira, Daniel A., Tsiperson, Vladislav, Reszka, Natalia, Taylor, Alexander B., Hart, P. John, Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
Published in Cell reports (Cambridge) (04.08.2015)
Published in Cell reports (Cambridge) (04.08.2015)
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Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis
Wheeler, Ryan, Yu, Xia, Hou, Caixia, Mitra, Prithiba, Chen, Jhong‐Min, Herkules, Frank, Ivanov, Dmitri N., Tsodikov, Oleg V., Rohr, Jürgen
Published in Angewandte Chemie International Edition (07.01.2020)
Published in Angewandte Chemie International Edition (07.01.2020)
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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins
Bowen, Nicole E., Temple, Joshua, Shepard, Caitlin, Oo, Adrian, Arizaga, Fidel, Kapoor-Vazirani, Priya, Persaud, Mirjana, Yu, Corey H., Kim, Dong-Hyun, Schinazi, Raymond F., Ivanov, Dmitri N., Diaz-Griffero, Felipe, Yu, David S., Xiong, Yong, Kim, Baek
Published in The Journal of biological chemistry (01.10.2021)
Published in The Journal of biological chemistry (01.10.2021)
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Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module
Biris, Nikolaos, Yang, Yang, Taylor, Alexander B., Tomashevski, Andrei, Guo, Miao, Hart, P. John, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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Acetylation of SAMHD1 at lysine 580 is crucial for blocking HIV-1 infection
Bulnes-Ramos, Angel, Schott, Kerstin, Rabinowitz, Jesse, Luchsinger, Charlotte, Bertelli, Cinzia, Miyagi, Eri, Yu, Corey H., Persaud, Mirjana, Shepard, Caitlin, König, Renate, Kim, Baek, Ivanov, Dmitri N., Strebel, Klaus, Diaz-Griffero, Felipe
Published in mBio (20.08.2024)
Published in mBio (20.08.2024)
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Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus
Lam, Tonika, Kulp, Dennis V, Wang, Rui, Lou, Zheng, Taylor, Julia, Rivera, Carlos E, Yan, Hui, Zhang, Qi, Wang, Zhonghua, Zan, Hong, Ivanov, Dmitri N, Zhong, Guangming, Casali, Paolo, Xu, Zhenming
Published in The Journal of immunology (1950) (15.11.2016)
Published in The Journal of immunology (1950) (15.11.2016)
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Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis
Wheeler, Ryan, Yu, Xia, Hou, Caixia, Mitra, Prithiba, Chen, Jhong‐Min, Herkules, Frank, Ivanov, Dmitri N., Tsodikov, Oleg V., Rohr, Jürgen
Published in Angewandte Chemie (07.01.2020)
Published in Angewandte Chemie (07.01.2020)
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Structural Insight into the DNA Binding Function of Transcription Factor ERF
Hou, Caixia, McCown, Claudia, Ivanov, Dmitri N, Tsodikov, Oleg V
Published in Biochemistry (Easton) (01.12.2020)
Published in Biochemistry (Easton) (01.12.2020)
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Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells
Wang, Zhonghua, Bhattacharya, Akash, Villacorta, Jessica, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
Published in The Journal of biological chemistry (07.10.2016)
Published in The Journal of biological chemistry (07.10.2016)
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Journal Article
Rhesus Monkey TRIM5α SPRY Domain Recognizes Multiple Epitopes That Span Several Capsid Monomers on the Surface of the HIV-1 Mature Viral Core
Biris, Nikolaos, Tomashevski, Andrei, Bhattacharya, Akash, Diaz-Griffero, Felipe, Ivanov, Dmitri N.
Published in Journal of molecular biology (13.12.2013)
Published in Journal of molecular biology (13.12.2013)
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Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect
Bhattacharya, Akash, Wang, Zhonghua, White, Tommy, Buffone, Cindy, Nguyen, Laura A, Shepard, Caitlin N, Kim, Baek, Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N
Published in Scientific reports (11.08.2016)
Published in Scientific reports (11.08.2016)
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Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair
Wang, Meiling, Li, Wenjing, Tomimatsu, Nozomi, Yu, Corey H., Ji, Jae-Hoon, Alejo, Salvador, Witus, Samuel R., Alimbetov, Dauren, Fitzgerald, O’Taveon, Wu, Bo, Wang, Qijing, Huang, Yuxin, Gan, Yaqi, Dong, Felix, Kwon, Youngho, Sareddy, Gangadhara R., Curiel, Tyler J., Habib, Amyn A., Hromas, Robert, dos Santos Passos, Carolina, Yao, Tingting, Ivanov, Dmitri N., Brzovic, Peter S., Burma, Sandeep, Klevit, Rachel E., Zhao, Weixing
Published in Molecular cell (19.10.2023)
Published in Molecular cell (19.10.2023)
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Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1
Hou, Caixia, Weidenbach, Stevi, Cano, Kristin E, Wang, Zhonghua, Mitra, Prithiba, Ivanov, Dmitri N, Rohr, Jürgen, Tsodikov, Oleg V
Published in Nucleic acids research (14.10.2016)
Published in Nucleic acids research (14.10.2016)
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General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins
Wagner, Jonathan M, Christensen, Devin E, Bhattacharya, Akash, Dawidziak, Daria M, Roganowicz, Marcin D, Wan, Yueping, Pumroy, Ruth A, Demeler, Borries, Ivanov, Dmitri N, Ganser-Pornillos, Barbie K, Sundquist, Wesley I, Pornillos, Owen
Published in Journal of virology (15.02.2018)
Published in Journal of virology (15.02.2018)
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Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells
Yi, Caihong, Li, Guiming, Ivanov, Dmitri N., Wang, Zhonghua, Velasco, Mitzli X., Hernández, Greco, Kaundal, Soni, Villarreal, Johanna, Gupta, Yogesh K., Qiao, Mei, Hubert, Christopher G., Hart, Matthew J., Penalva, Luiz O.F.
Published in RNA biology (02.11.2018)
Published in RNA biology (02.11.2018)
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