DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex
Zhang, Jun, Chalmers, Michael J, Stayrook, Keith R, Burris, Lorri L, Wang, Yongjun, Busby, Scott A, Pascal, Bruce D, Garcia-Ordonez, Ruben D, Bruning, John B, Istrate, Monica A, Kojetin, Douglas J, Dodge, Jeffrey A, Burris, Thomas P, Griffin, Patrick R
Published in Nature structural & molecular biology (01.05.2011)
Published in Nature structural & molecular biology (01.05.2011)
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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
Solt, Laura A., Kumar, Naresh, Nuhant, Philippe, Wang, Yongjun, Lauer, Janelle L., Liu, Jin, Istrate, Monica A., Kamenecka, Theodore M., Roush, William R., Vidović, Dušica, Schürer, Stephan C., Xu, Jihong, Wagoner, Gail, Drew, Paul D., Griffin, Patrick R., Burris, Thomas P.
Published in Nature (London) (28.04.2011)
Published in Nature (London) (28.04.2011)
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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist
Kumar, Naresh, Solt, Laura A, Conkright, Juliana J, Wang, Yongjun, Istrate, Monica A, Busby, Scott A, Garcia-Ordonez, Ruben D, Burris, Thomas P, Griffin, Patrick R
Published in Molecular pharmacology (01.02.2010)
Published in Molecular pharmacology (01.02.2010)
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Identification of SR1078, a Synthetic Agonist for the Orphan Nuclear Receptors RORα and RORγ
Wang, Yongjun, Kumar, Naresh, Nuhant, Philippe, Cameron, Michael D, Istrate, Monica A, Roush, William R, Griffin, Patrick R, Burris, Thomas P
Published in ACS chemical biology (19.11.2010)
Published in ACS chemical biology (19.11.2010)
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Identification of a Novel Non-retinoid Pan Inverse Agonist of the Retinoic Acid Receptors
Busby, Scott A, Kumar, Naresh, Kuruvilla, Dana S, Istrate, Monica A, Conkright, Juliana J, Wang, Yongjun, Kamenecka, Theodore M, Cameron, Michael D, Roush, William R, Burris, Thomas P, Griffin, Patrick R
Published in ACS chemical biology (17.06.2011)
Published in ACS chemical biology (17.06.2011)
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Development of an HTS-compatible assay for discovery of RORα modulators using AlphaScreen® technology
Istrate, Monica A, Spicer, Timothy P, Wang, Yan, Bernard, Jerrold A, Helvering, Leah M, Bocchinfuso, Wayne P, Richardson, Timothy I, Zink, Richard, Kumar, Naresh, Montrose-Rafizadeh, Chahrzad, Dodge, Jeffrey, Hodder, Peter, Griffin, Patrick R
Published in Journal of biomolecular screening (01.02.2011)
Published in Journal of biomolecular screening (01.02.2011)
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Suppression of T^sub H^17 differentiation and autoimmunity by a synthetic ROR ligand
Solt, Laura A, Kumar, Naresh, Nuhant, Philippe, Wang, Yongjun, Lauer, Janelle L, Liu, Jin, Istrate, Monica A, Kamenecka, Theodore M, Roush, William R, Vidovic, Dusica, Schürer, Stephan C, Xu, Jihong, Wagoner, Gail, Drew, Paul D, Griffin, Patrick R, Burris, Thomas P
Published in Nature (London) (28.04.2011)
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Published in Nature (London) (28.04.2011)
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Suppression of [T.sub.H]17 differentiation and autoimmunity by a synthetic ROR ligand
Solt, Laura A, Kumar, Naresh, Nuhant, Philippe, Wang, Yongjun, Lauer, Janelle L, Liu, Jin, Istrate, Monica A, Kamenecka, Theodore M, Roush, William R, Vidovic, DuSica, Schurer, Stephan C, Xu, Jihong, Wagoner, Gail, Drew, Paul D, Griffin, Patrick R, Burris, Thomas P
Published in Nature (London) (28.04.2011)
Published in Nature (London) (28.04.2011)
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Journal Article
Suppression of T sub(H)17 differentiation and autoimmunity by a synthetic ROR ligand
Solt, Laura A, Kumar, Naresh, Nuhant, Philippe, Wang, Yongjun, Lauer, Janelle L, Liu, Jin, Istrate, Monica A, Kamenecka, Theodore M, Roush, William R, Vidovic, Dusica, Schuerer, Stephan C, Xu, Jihong, Wagoner, Gail, Drew, Paul D, Griffin, Patrick R, Burris, Thomas P
Published in Nature (London) (08.04.2011)
Published in Nature (London) (08.04.2011)
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Journal Article
The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist
Naresh Kumar, Laura A. Solt, Juliana J. Conkright, Yongjun Wang, Monica A. Istrate, Scott A. Busby, Ruben D. Garcia-Ordonez, Thomas P. Burris, Patrick R. Griffin
Published in Molecular pharmacology (01.02.2010)
Published in Molecular pharmacology (01.02.2010)
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Journal Article
Identification of a Synthetic Agonist for the Orphan Nuclear Receptors RORα and RORγ, SR1078
Wang, Yongjun, Kumar, Naresh, Nuhant, Philippe, Cameron, Michael D., Istrate, Monica A., Roush, William R., Griffin, Patrick R., Burris, Thomas P.
Published in ACS chemical biology (19.11.2010)
Published in ACS chemical biology (19.11.2010)
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