ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis
Shi, Y, Nikulenkov, F, Zawacka-Pankau, J, Li, H, Gabdoulline, R, Xu, J, Eriksson, S, Hedström, E, Issaeva, N, Kel, A, Arnér, E S J, Selivanova, G
Published in Cell death and differentiation (01.04.2014)
Published in Cell death and differentiation (01.04.2014)
Get full text
Journal Article
sROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis
Shi, Y, Nikulenkov, F, Zawacka-Pankau, J, Li, H, Gabdoulline, R, Xu, J, Eriksson, S, Hedstroem, E, Issaeva, N, Kel, A
Published in Cell death and differentiation (01.04.2014)
Published in Cell death and differentiation (01.04.2014)
Get full text
Journal Article
TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior
Ivanov, S V, Panaccione, A, Brown, B, Guo, Y, Moskaluk, C A, Wick, M J, Brown, J L, Ivanova, A V, Issaeva, N, El-Naggar, A K, Yarbrough, W G
Published in Oncogene (08.08.2013)
Published in Oncogene (08.08.2013)
Get full text
Journal Article
Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner
Wamsley, J J, Gary, C, Biktasova, A, Hajek, M, Bellinger, G, Virk, R, Issaeva, N, Yarbrough, W G
Published in Oncogenesis (New York, NY) (10.04.2017)
Published in Oncogenesis (New York, NY) (10.04.2017)
Get full text
Journal Article
Predictive Genetic Biomarkers of Survival in HPV-associated HNSCC
Yarbrough, W., Issaeva, N.
Published in International journal of radiation oncology, biology, physics (01.04.2020)
Published in International journal of radiation oncology, biology, physics (01.04.2020)
Get full text
Journal Article
191 (PB179): Novel strategy to improve response of high risk HPV+ HNSCC to radiation therapy
Vemulamanda, S., Kothari, A., Schrank, T., Yarbrough, W.G., Issaeva, N.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
Get full text
Journal Article
Predictive Molecular Biomarkers for HPV-Associated Head and Neck Squamous Cell Carcinoma
Yarbrough, W., Schrank, T.P., Blumberg, J., Patel, S., Hackman, T., Lumley, C., Burtness, B., Issaeva, N.
Published in International journal of radiation oncology, biology, physics (01.04.2022)
Published in International journal of radiation oncology, biology, physics (01.04.2022)
Get full text
Journal Article
HPV16-A1 Genotype is Associated with Poor Recurrence-Free Survival in HPV16 Associated Squamous Cell Carcinoma of the Oropharynx
Schrank, T.P., Landess, L., Stepp, W.H., Rehmani, H., Weir, W., Lenze, N., Lal, A., Jefferys, S., Blumberg, J., Patel, S., Lumley, C., Hackman, T., Issaeva, N., Yarbrough, W.
Published in International journal of radiation oncology, biology, physics (01.04.2022)
Published in International journal of radiation oncology, biology, physics (01.04.2022)
Get full text
Journal Article
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
Selivanova, Galina, Issaeva, Natalia, Bozko, Przemyslaw, Enge, Martin, Protopopova, Marina, Verhoef, Lisette G G C, Masucci, Maria, Pramanik, Aladdin
Published in Nature medicine (01.12.2004)
Published in Nature medicine (01.12.2004)
Get full text
Journal Article
Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers
Zhang, Jialing, Chen, Tony, Yang, Xinping, Cheng, Hui, Späth, Stephan S, Clavijo, Paul E, Chen, Jianhong, Silvin, Christopher, Issaeva, Natalia, Su, Xiulan, Yarbrough, Wendell G, Annunziata, Christina M, Chen, Zhong, Van Waes, Carter
Published in Cancer research (Chicago, Ill.) (15.08.2018)
Published in Cancer research (Chicago, Ill.) (15.08.2018)
Get full text
Journal Article
Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival
GUBANOVA, Evgenia, BROWN, Brandee, IVANOV, Sergei V, HELLEDAY, Thomas, MILLS, Gordon B, YARBROUGH, Wendell G, ISSAEVA, Natalia
Published in Clinical cancer research (01.03.2012)
Published in Clinical cancer research (01.03.2012)
Get full text
Journal Article
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
Wiman, Klas G, Bykov, Vladimir J.N, Issaeva, Natalia, Shilov, Alexandre, Hultcrantz, Monica, Pugacheva, Elena, Chumakov, Peter, Bergman, Jan, Selivanova, Galina
Published in Nature medicine (01.03.2002)
Published in Nature medicine (01.03.2002)
Get full text
Journal Article
Reactivation of Mutant p53 and Induction of Apoptosis in Human Tumor Cells by Maleimide Analogs
Bykov, Vladimir J.N., Issaeva, Natalia, Zache, Nicole, Shilov, Alexandre, Hultcrantz, Monica, Bergman, Jan, Selivanova, Galina, Wiman, Klas G.
Published in The Journal of biological chemistry (26.08.2005)
Published in The Journal of biological chemistry (26.08.2005)
Get full text
Journal Article
PRIMA-1Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo
Bao, Wenjie, Chen, Ming, Zhao, Xu, Kumar, Ravjiv, Spinnler, Clemens, Thullberg, Minna, Issaeva, Natalia, Selivanova, Galina, Stromblad, Staffan
Published in Cell cycle (Georgetown, Tex.) (15.01.2011)
Published in Cell cycle (Georgetown, Tex.) (15.01.2011)
Get full text
Journal Article
Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database
Bykov, Vladimir J.N., Issaeva, Natalia, Selivanova, Galina, Wiman, Klas G.
Published in Carcinogenesis (New York) (01.12.2002)
Published in Carcinogenesis (New York) (01.12.2002)
Get full text
Journal Article
RPA Mediates Recombination Repair During Replication Stress and Is Displaced from DNA by Checkpoint Signalling in Human Cells
Sleeth, Kate M., Sørensen, Claus Storgaard, Issaeva, Natalia, Dziegielewski, Jaroslaw, Bartek, Jiri, Helleday, Thomas
Published in Journal of molecular biology (12.10.2007)
Published in Journal of molecular biology (12.10.2007)
Get full text
Journal Article
Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule
Grinkevich, Vera V, Vema, Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R, Hedström, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlén, Anders, Wilhelm, Margareta, Barran, Perdita E, Okorokov, Andrei L, Selivanova, Galina, Zawacka-Pankau, Joanna E
Published in Frontiers in molecular biosciences (01.06.2022)
Published in Frontiers in molecular biosciences (01.06.2022)
Get full text
Journal Article
Rescue of Mutants of the Tumor Suppressor p53 in Cancer Cells by a Designed Peptide
Issaeva, Natalia, Friedler, Assaf, Bozko, Przemyslaw, Wiman, Klas G., Fersht, Alan R., Selivanova, Galina
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2003)
Get full text
Journal Article