MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice
Hense, Jessica D., Garcia, Driele N., Zanini, Bianka M., Barreto, Mariana M., Perreira, Giulia C., Isola, José V. V., de Brito, Camila, Fornalik, Michal, Mondal, Samim A., Ávila, Bianca M., Oliveira, Thais L., Rice, Heather C., Lacy, Charles I., Vaucher, Rodrigo A., Mason, Jeffrey B., Masternak, Michal M., Stout, Michael B., Schneider, Augusto
Published in Scientific reports (27.07.2024)
Published in Scientific reports (27.07.2024)
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Journal Article
Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletion
Ansere, Victor A., Ali-Mondal, Samim, Sathiaseelan, Roshini, Garcia, Driele N., Isola, José V.V., Henseb, Jéssica D., Saccon, Tatiana D., Ocañas, Sarah R., Tooley, Kyla B., Stout, Michael B., Schneider, Augusto, Freeman, Willard M.
Published in Mechanisms of ageing and development (01.03.2021)
Published in Mechanisms of ageing and development (01.03.2021)
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Journal Article
17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice
Ali Mondal, Samim, Sathiaseelan, Roshini, Mann, Shivani N, Kamal, Maria, Luo, Wenyi, Saccon, Tatiana D, Isola, José V V, Peelor, 3rd, Frederick F, Li, Tiangang, Freeman, Willard M, Miller, Benjamin F, Stout, Michael B
Published in American journal of physiology: endocrinology and metabolism (01.02.2023)
Published in American journal of physiology: endocrinology and metabolism (01.02.2023)
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Journal Article
A single-cell atlas of the aging mouse ovary
Isola, José V V, Ocañas, Sarah R, Hubbart, Chase R, Ko, Sunghwan, Mondal, Samim Ali, Hense, Jessica D, Carter, Hannah N C, Schneider, Augusto, Kovats, Susan, Alberola-Ila, José, Freeman, Willard M, Stout, Michael B
Published in Nature aging (01.01.2024)
Published in Nature aging (01.01.2024)
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Journal Article
The role of cellular senescence in ovarian aging
Hense, Jéssica D., Isola, José V. V., Garcia, Driele N., Magalhães, Larissa S., Masternak, Michal M., Stout, Michael B., Schneider, Augusto
Published in npj aging (20.07.2024)
Published in npj aging (20.07.2024)
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Journal Article
Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
Ocañas, Sarah R, Isola, José V V, Saccon, Tatiana D, Pham, Kevin D, Chucair-Elliott, Ana J, Schneider, Augusto, Freeman, Willard M, Stout, Michael B
Published in Journal of visualized experiments (24.02.2023)
Published in Journal of visualized experiments (24.02.2023)
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Journal Article
17α-estradiol does not adversely affect sperm parameters or fertility in male mice: implications for reproduction-longevity trade-offs
Isola, José V. V., Veiga, Gabriel B., de Brito, Camila R. C., Alvarado-Rincón, Joao A., Garcia, Driele N., Zanini, Bianka M., Hense, Jéssica D., Vieira, Arnaldo D., Garratt, Michael, Gasperin, Bernardo G., Schneider, Augusto, Stout, Michael B.
Published in GeroScience (01.08.2023)
Published in GeroScience (01.08.2023)
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Journal Article
Dasatinib and quercetin increase testosterone and sperm concentration in mice
Garcia, Driele N, Hense, Jéssica D, Zanini, Bianka M, Isola, José V V, Pradiee, Jorgea, Prosczek, Juliane B, Alvarado-Rincón, Joao A, Mondadori, Rafael G, Mason, Jeffrey B, Brieño-Enríquez, Miguel A, Barros, Carlos C, Stout, Michael B, Masternak, Michal M, Schneider, Augusto
Published in Physiology international (12.06.2023)
Published in Physiology international (12.06.2023)
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Journal Article
Reproductive Ageing: Inflammation, immune cells, and cellular senescence in the aging ovary
Isola, José V V, Hense, Jessica D, Osório, César A P, Biswas, Subhasri, Alberola-Ila, José, Ocañas, Sarah R, Schneider, Augusto, Stout, Michael B
Published in Reproduction (Cambridge, England) (01.08.2024)
Published in Reproduction (Cambridge, England) (01.08.2024)
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Journal Article
Mild calorie restriction, but not 17α-estradiol, extends ovarian reserve and fertility in female mice
Isola, José V.V., Zanini, Bianka M., Hense, Jessica D., Alvarado-Rincón, Joao A., Garcia, Driele N., Pereira, Giulia C., Vieira, Arnaldo D., Oliveira, Thais L., Collares, Tiago, Gasperin, Bernardo G., Stout, Michael B., Schneider, Augusto
Published in Experimental gerontology (01.03.2022)
Published in Experimental gerontology (01.03.2022)
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Journal Article
17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates
Isola, José V.V., Zanini, Bianka M., Sidhom, Silvana, Kopchick, John J., Bartke, Andrzej, Masternak, Michal M., Stout, Michael B., Schneider, Augusto
Published in Experimental gerontology (01.01.2020)
Published in Experimental gerontology (01.01.2020)
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Journal Article
Effects of calorie, protein, and branched chain amino acid restriction on ovarian aging in mice
Veiga, Gabriel B., Zanini, Bianka M., Garcia, Driele Neske, Hense, Jéssica D., Barreto, Mariana M., Isola, José V.V., Mondadori, Rafael G., Masternak, Michal M., Stout, Michael B., Schneider, Augusto
Published in Reproductive biology (01.03.2024)
Published in Reproductive biology (01.03.2024)
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Journal Article
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary
Hense, Jéssica D., Garcia, Driele N., Isola, José V., Alvarado-Rincón, Joao A., Zanini, Bianka M., Prosczek, Juliane B., Stout, Michael B., Mason, Jeffrey B., Walsh, Patrick T., Brieño-Enríquez, Miguel A., Schadock, Ines, Barros, Carlos C., Masternak, Michal M., Schneider, Augusto
Published in GeroScience (01.06.2022)
Published in GeroScience (01.06.2022)
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Journal Article
Senolytic treatment fails to improve ovarian reserve or fertility in female mice
Garcia, Driele N., Hense, Jessica D., Zanini, Bianka M., Isola, Jose V. V., Prosczek, Juliane B., Ashiqueali, Sarah, Oliveira, Thais L., Mason, Jeffrey B., Schadock, Ines C., Barros, Carlos C., Stout, Michael B., Masternak, Michal M., Schneider, Augusto
Published in GeroScience (01.06.2024)
Published in GeroScience (01.06.2024)
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Journal Article
Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques
Stout, Michael B., Vaughan, Kelli L., Isola, Jose V. V., Mann, Shivani N., Wellman, Bayli, Hoffman, Jessica M., Porter, Hunter L., Freeman, Willard M., Mattison, Julie A.
Published in GeroScience (01.08.2023)
Published in GeroScience (01.08.2023)
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Journal Article
A single-cell atlas of the aging murine ovary
Isola, José V V, Ocañas, Sarah R, Hubbart, Chase R, Ko, Sunghwan, Mondal, Samim Ali, Hense, Jessica D, Carter, Hannah N C, Schneider, Augusto, Kovats, Susan, Alberola-Ila, José, Freeman, Willard M, Stout, Michael B
Published in bioRxiv : the preprint server for biology (06.09.2023)
Published in bioRxiv : the preprint server for biology (06.09.2023)
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Journal Article
A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus)
Sathiaseelan, Roshini, Isola, Jose V V, Santín-Márquez, Roberto, Adekunbi, Daniel, Fornalik, Michal, Salmon, Adam B, Stout, Michael B
Published in GeroScience (06.08.2024)
Published in GeroScience (06.08.2024)
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Journal Article
Role of Estrogen Receptor α in Aging and Chronic Disease
Published in Advances in Geriatric Medicine and Research
(2023)
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Journal Article