Synthesis and biological evaluation of novel orally available 1-phenyl-6-aminouracils containing dimethyldihydrobenzofuranol structure for the treatment of allergic skin diseases
Tobe, Masanori, Tsuboi, Katsunori, Hasegawa, Futoshi, Fujiwara, Norio, Inoue, Yoshifumi, Isobe, Masakazu, Isobe, Yoshiaki
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex
Kimura, Tomoki, Li, Yong, Okumura, Fumika, Itoh, Norio, Nakanishi, Tsuyoshi, Sone, Tomomichi, Isobe, Masakazu, Andrews, Glen K
Published in Biochemical journal (01.11.2008)
Published in Biochemical journal (01.11.2008)
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The zinc-sensing transcription factor MTF-1 mediates zinc-induced epigenetic changes in chromatin of the mouse metallothionein-I promoter
Okumura, Fumika, Li, Yong, Itoh, Norio, Nakanishi, Tsuyoshi, Isobe, Masakazu, Andrews, Glen K., Kimura, Tomoki
Published in Biochimica et biophysica acta (2011)
Published in Biochimica et biophysica acta (2011)
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Involvement of Human Blood Arylesterases and Liver Microsomal Carboxylesterases in Nafamostat Hydrolysis
Yamaori, Satoshi, Fujiyama, Nobuhiro, Kushihara, Mika, Funahashi, Tatsuya, Kimura, Toshiyuki, Yamamoto, Ikuo, Sone, Tomomichi, Isobe, Masakazu, Ohshima, Tohru, Matsumura, Kenji, Oda, Minoru, Watanabe, Kazuhito
Published in Drug metabolism and pharmacokinetics (01.01.2006)
Published in Drug metabolism and pharmacokinetics (01.01.2006)
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Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300
Kimura, Tomoki, Okumura, Fumika, Onodera, Akira, Nakanishi, Tsuyoshi, Itoh, Norio, Isobe, Masakazu
Published in Journal of toxicological sciences (01.04.2011)
Published in Journal of toxicological sciences (01.04.2011)
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The Combined Effect of Topical CX-659S, a Novel Diaminouracil Derivative, With Topical Corticosteroid on the Three Types of Allergic Responses in Mice or Guinea Pigs
Inoue, Yoshifumi, Isobe, Masakazu, Hayashi, Hideya
Published in Journal of Pharmacological Sciences (2003)
Published in Journal of Pharmacological Sciences (2003)
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Inhibitory Activity of CX-659S, a Novel Diaminouracil Derivative, against the Rebound Phenomenon following Withdrawal of Corticosteroid Therapy for Chronic Contact Hypersensitivity Responses
Inoue, Yoshifumi, Isobe, Masakazu, Shiohara, Tetsuo, Hayashi, Hideya
Published in International archives of allergy and immunology (01.06.2003)
Published in International archives of allergy and immunology (01.06.2003)
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Metal Response Element-binding Transcription Factor-1 Is Activated by Degradation of Metallothionein
Kimura, Tomoki, Okumura, Fumika, Oguro, Ikuyo, Nakanishi, Tsuyoshi, Sone, Tomomichi, Isobe, Masakazu, Tanaka, Keiichi, Itoh, Norio
Published in Journal of Health Science (01.01.2009)
Published in Journal of Health Science (01.01.2009)
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Involvement of Human Blood Arylesterases and Liver Microsomal Carboxylesterases in Nafamostat Hydrolysis
Satoshi YAMAORI, Nobuhiro FUJIYAMA, Mika KUSHIHARA, Tatsuya FUNAHASHI, Toshiyuki KIMURA, Ikuo YAMAMOTO, Tomomichi SONE, Masakazu ISOBE, Tohru OHSHIMA, Kenji MATSUMURA, Minoru ODA, Kazuhito WATANABE
Published in DRUG METABOLISM AND PHARMACOKINETICS (2006)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (2006)
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Suppressive Effect of Topically Applied CX-659S, a Novel Diaminouracil Derivative, on the Contact Hypersensitivity Reaction in Various Animal Models
Goto, Yuso, Inoue, Yoshifumi, Tsuchiya, Masami, Isobe, Masakazu, Ueno, Takamasa, Uchi, Hiroshi, Furue, Masutaka, Hayashi, Hideya
Published in International archives of allergy and immunology (01.12.2000)
Published in International archives of allergy and immunology (01.12.2000)
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Assessment of Benzydamine N-Oxidation Mediated by Flavin-Containing Monooxygenase in Different Regions of Rat Brain and Liver Using Microdialysis
KAWAJI, Akiko, YAMAGUCHI, Tomohiro, TOCHINO, Yoshihiro, ISOBE, Masakazu, TAKABATAKE, Eigo
Published in Biological & pharmaceutical bulletin (01.01.1999)
Published in Biological & pharmaceutical bulletin (01.01.1999)
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Protective Effect of Zinc against Lipopolysaccharide/D-Galactosamine-Induced Lethality
Kimura, Tomoki, Itoh, Norio, Takehara, Miyako, Oguro, Ikuyo, Ishizaki, Jun-ichi, Nakanishi, Tsuyoshi, Isobe, Masakazu, Tanaka, Keiichi
Published in Journal of Health Science (01.01.2003)
Published in Journal of Health Science (01.01.2003)
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