Systemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease
Mandolfo, Oriana, Parker, Helen, Aguado, Èlia, Ishikawa Learmonth, Yuko, Liao, Ai Yin, O’Leary, Claire, Ellison, Stuart, Forte, Gabriella, Taylor, Jessica, Wood, Shaun, Searle, Rachel, Holley, Rebecca J, Boutin, Hervé, Bigger, Brian W
Published in EMBO molecular medicine (15.07.2024)
Published in EMBO molecular medicine (15.07.2024)
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Journal Article
Generation of a novel immunodeficient mouse model of Mucopolysaccharidosis type IIIA to test human stem cell-based therapies
Mandolfo, Oriana, Parker, Helen, Usman, Asma'u, Learmonth, Yuko Ishikawa, Holley, Rebecca J., MacDonald, Andrew, McKay, Tristan, Bigger, Brian
Published in Molecular genetics and metabolism (01.09.2024)
Published in Molecular genetics and metabolism (01.09.2024)
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Journal Article
Developing an iPSC-based neural gene therapy approach for MPS IIIA
Mandolfo, Oriana, Learmonth, Yuko Ishikawa, Usman, Asma'u, Andreou, Tereza, Taylor, Jessica, Parker, Helen, McKay, Tristan, Bigger, Brian
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Systemic inflammation leads to neuronal loss and exacerbates behavioural deficits in a mouse model of MPS IIIA
Mandolfo, Oriana, Parker, Helen, Aguado, Èlia, Learmonth, Yuko Ishikawa, Liao, Aiyin, O'Leary, Claire, Ellison, Stuart M., Taylor, Jessica, Wood, Shaun R., Holley, Rebecca, Boutin, Herve, Bigger, Brian
Published in Molecular genetics and metabolism (01.02.2024)
Published in Molecular genetics and metabolism (01.02.2024)
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Journal Article
Clinical outcomes and sustained biochemical engraftment following ex-vivo autologous stem cell gene therapy for mucopolysaccharidosis type IIIA
Jones, Simon, Kinsella, Jane, Holley, Rebecca J., Potter, Jane, Booth, Claire, Buckland, Karen, Rust, Stewart, Bromley, Rebecca, Church, Heather J., Lee, Helena, Ford, Laura, Learmonth, Yuko Ishikawa, Searle, Rachel, Ellison, Stuart M., Wynn, Robert, Bigger, Brian
Published in Molecular genetics and metabolism (01.02.2024)
Published in Molecular genetics and metabolism (01.02.2024)
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