Metabolic regulation of osteoclast differentiation and function
Indo, Yoriko, Takeshita, Sunao, Ishii, Kiyo‐Aki, Hoshii, Takayuki, Aburatani, Hiroyuki, Hirao, Atsushi, Ikeda, Kyoji
Published in Journal of bone and mineral research (01.11.2013)
Published in Journal of bone and mineral research (01.11.2013)
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Journal Article
LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH
Takata, Noboru, Ishii, Kiyo-Aki, Takayama, Hiroaki, Nagashimada, Mayumi, Kamoshita, Kyoko, Tanaka, Takeo, Kikuchi, Akihiro, Takeshita, Yumie, Matsumoto, Yukako, Ota, Tsuguhito, Yamamoto, Yasuhiko, Yamagoe, Satoshi, Seki, Akihiro, Sakai, Yoshio, Kaneko, Shuichi, Takamura, Toshinari
Published in Scientific reports (12.01.2021)
Published in Scientific reports (12.01.2021)
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Journal Article
Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
Misu, Hirofumi, Takayama, Hiroaki, Saito, Yoshiro, Mita, Yuichiro, Kikuchi, Akihiro, Ishii, Kiyo-Aki, Chikamoto, Keita, Kanamori, Takehiro, Tajima, Natsumi, Lan, Fei, Takeshita, Yumie, Honda, Masao, Tanaka, Mutsumi, Kato, Seiji, Matsuyama, Naoto, Yoshioka, Yuya, Iwayama, Kaito, Tokuyama, Kumpei, Akazawa, Nobuhiko, Maeda, Seiji, Takekoshi, Kazuhiro, Matsugo, Seiichi, Noguchi, Noriko, Kaneko, Shuichi, Takamura, Toshinari
Published in Nature medicine (01.04.2017)
Published in Nature medicine (01.04.2017)
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Journal Article
Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes
Kamoshita, Kyoko, Ishii, Kiyo-Aki, Tahira, Yumiko, Kikuchi, Akihiro, Abuduwaili, Halimulati, Tajima-Shirasaki, Natsumi, Li, Qifang, Takayama, Hiroaki, Matsumoto, Kunio, Takamura, Toshinari
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
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Journal Article
Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases
Abuduwaili, Halimulati, Kamoshita, Kyoko, Ishii, Kiyo-Aki, Takahashi, Kenta, Abuduyimiti, Tuerdiguli, Qifang, Li, Isobe, Yuki, Goto, Hisanori, Nakano, Yujiro, Takeshita, Yumie, Takayama, Hiroaki, Harada, Kenichi, Takamura, Toshinari
Published in American journal of physiology: endocrinology and metabolism (01.06.2023)
Published in American journal of physiology: endocrinology and metabolism (01.06.2023)
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Journal Article
Photothermal excitation efficiency enhancement of cantilevers by electron beam deposition of amorphous carbon thin films
Penedo, Marcos, Yurtsever, Ayhan, Miyazawa, Keisuke, Furusho, Hirotoshi, Ishii, Kiyo-Aki, Fukuma, Takeshi
Published in Scientific reports (15.10.2020)
Published in Scientific reports (15.10.2020)
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Journal Article
Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes
Tajima-Shirasaki, Natsumi, Ishii, Kiyo-aki, Takayama, Hiroaki, Shirasaki, Takayoshi, Iwama, Hisakazu, Chikamoto, Keita, Saito, Yoshiro, Iwasaki, Yasumasa, Teraguchi, Atsushi, Lan, Fei, Kikuchi, Akihiro, Takeshita, Yumie, Murao, Koji, Matsugo, Seiichi, Kaneko, Shuichi, Misu, Hirofumi, Takamura, Toshinari
Published in The Journal of biological chemistry (30.06.2017)
Published in The Journal of biological chemistry (30.06.2017)
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Journal Article
PAC1 Deficiency Protects Obese Male Mice From Immobilization-Induced Muscle Atrophy by Suppressing FoxO–Atrogene Axis
Li, Qifang, Ishii, Kiyo-aki, Kamoshita, Kyoko, Takahashi, Kenta, Abuduwaili, Halimulati, Takayama, Hiroaki, Galicia-Medina, Cynthia M, Tanida, Ryota, Ko Oo, Hein, Gafiyatullina, Guzel, Yao, Xingyu, Abuduyimiti, Tuerdiguli, Hamazaki, Jun, Goto, Hisanori, Nakano, Yujiro, Takeshita, Yumie, Harada, Kenichi, Murata, Shigeo, Takamura, Toshinari
Published in Endocrinology (Philadelphia) (17.04.2023)
Published in Endocrinology (Philadelphia) (17.04.2023)
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Journal Article
Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Shirasaki, Takayoshi, Yamagoe, Satoshi, Shimakami, Tetsuro, Murai, Kazuhisa, Imamura, Ryu, Ishii, Kiyo-Aki, Takayama, Hiroaki, Matsumoto, Yukako, Tajima-Shirasaki, Natsumi, Nagata, Naoto, Shimizu, Ryogo, Yamanaka, Souma, Abe, Atsushi, Omura, Hitoshi, Kawaguchi, Kazunori, Okada, Hikari, Yamashita, Taro, Yoshikawa, Tomoki, Takimoto, Kazuhiro, Taharaguchi, Motoko, Takatsuka, Shogo, Miyazaki, Yoshitsugu, Tamai, Toshikatsu, Tanabe, Yamato, Kurachi, Makoto, Yamamoto, Yasuhiko, Kaneko, Shuichi, Matsumoto, Kunio, Takamura, Toshinari, Honda, Masao
Published in Nature communications (08.06.2022)
Published in Nature communications (08.06.2022)
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Journal Article
Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes
Takeshita, Yumie, Teramura, Chisato, Kamoshita, Kyoko, Takayama, Hiroaki, Nakagawa, Hiromi, Enyama, Yasufumi, Ishii, Kiyo‐Aki, Tanaka, Takeo, Goto, Hisanori, Nakano, Yujiro, Osada, Sachie, Tanaka, Yoshiaki, Tokuyama, Kumpei, Takamura, Toshinari
Published in Journal of diabetes investigation (01.03.2022)
Published in Journal of diabetes investigation (01.03.2022)
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Journal Article
Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice
Chikamoto, Keita, Misu, Hirofumi, Takayama, Hiroaki, Kikuchi, Akihiro, Ishii, Kiyo-aki, Lan, Fei, Takata, Noboru, Tajima-Shirasaki, Natsumi, Takeshita, Yumie, Tsugane, Hirohiko, Kaneko, Shuichi, Matsugo, Seiichi, Takamura, Toshinari
Published in Biochemical and biophysical research communications (23.09.2016)
Published in Biochemical and biophysical research communications (23.09.2016)
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Journal Article
Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity
Murai, Kazuhisa, Honda, Masao, Shirasaki, Takayoshi, Shimakami, Tetsuro, Omura, Hitoshi, Misu, Hirofumi, Kita, Yuki, Takeshita, Yumie, Ishii, Kiyo-aki, Takamura, Toshinari, Urabe, Takeshi, Shimizu, Ryogo, Okada, Hikari, Yamashita, Taro, Sakai, Yoshio, Kaneko, Shuichi
Published in Cell host & microbe (10.04.2019)
Published in Cell host & microbe (10.04.2019)
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Journal Article
Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans
Mohri, Kensuke, Misu, Hirofumi, Takayama, Hiroaki, Ishii, Kiyo-aki, Kikuchi, Akihiro, Lan, Fei, Enyama, Yasufumi, Takeshita, Yumie, Saito, Yoshiro, Kaneko, Shuichi, Takamura, Toshinari
Published in Biological & pharmaceutical bulletin (01.03.2019)
Published in Biological & pharmaceutical bulletin (01.03.2019)
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Journal Article
Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice
Kikuchi, Akihiro, Takayama, Hiroaki, Tsugane, Hirohiko, Shiba, Kazuhiro, Chikamoto, Keita, Yamamoto, Tatsuya, Matsugo, Seiichi, Ishii, Kiyo-Aki, Misu, Hirofumi, Takamura, Toshinari
Published in Scientific reports (06.08.2020)
Published in Scientific reports (06.08.2020)
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Journal Article
Mineralocorticoid receptor function in bone metabolism and its role in glucocorticoid-induced osteopenia
Fumoto, Toshio, Ishii, Kiyo-aki, Ito, Masako, Berger, Stefan, Schütz, Günther, Ikeda, Kyoji
Published in Biochemical and biophysical research communications (09.05.2014)
Published in Biochemical and biophysical research communications (09.05.2014)
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Journal Article
Loss of SDHB Elevates Catecholamine Synthesis and Secretion Depending on ROS Production and HIF Stabilization
Saito, Yuria, Ishii, Kiyo-aki, Aita, Yuichi, Ikeda, Tatsuhiko, Kawakami, Yasushi, Shimano, Hitoshi, Hara, Hisato, Takekoshi, Kazuhiro
Published in Neurochemical research (01.04.2016)
Published in Neurochemical research (01.04.2016)
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Journal Article
Osteosarcoma-Derived Small Extracellular Vesicles Enhance Tumor Metastasis and Suppress Osteoclastogenesis by miR-146a-5p
Araki, Yoshihiro, Aiba, Hisaki, Yoshida, Takeshi, Yamamoto, Norio, Hayashi, Katsuhiro, Takeuchi, Akihiko, Miwa, Shinji, Igarashi, Kentaro, Nguyen, Tuan D, Ishii, Kiyo-Aki, Nojima, Takayuki, Takahashi, Satoru, Murakami, Hideki, Tsuchiya, Hiroyuki, Hanayama, Rikinari
Published in Frontiers in oncology (04.05.2021)
Published in Frontiers in oncology (04.05.2021)
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Journal Article
p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes
Igawa, Hirobumi, Kikuchi, Akihiro, Misu, Hirofumi, Ishii, Kiyo‐aki, Kaneko, Shuichi, Takamura, Toshinari
Published in Journal of diabetes investigation (01.01.2019)
Published in Journal of diabetes investigation (01.01.2019)
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Journal Article
Inhibition of Autophagy Enhances Sunitinib-Induced Cytotoxicity in Rat Pheochromocytoma PC12 cells
Ikeda, Tatsuhiko, Ishii, Kiyo-aki, Saito, Yuria, Miura, Masahiro, Otagiri, Aoi, Kawakami, Yasushi, Shimano, Hitoshi, Hara, Hisato, Takekoshi, Kazuhiro
Published in Journal of Pharmacological Sciences (01.01.2013)
Published in Journal of Pharmacological Sciences (01.01.2013)
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Journal Article
Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD
Saito, Yuria, Tanaka, Yuko, Aita, Yuichi, Ishii, Kiyo-Aki, Ikeda, Tatsuhiko, Isobe, Kazumasa, Kawakami, Yasushi, Shimano, Hitoshi, Hara, Hisato, Takekoshi, Kazuhiro
Published in American journal of physiology: endocrinology and metabolism (15.03.2012)
Published in American journal of physiology: endocrinology and metabolism (15.03.2012)
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