The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms
Balbinot, Camille, Armant, Olivier, Elarouci, Nabila, Marisa, Laetitia, Martin, Elisabeth, De Clara, Etienne, Onea, Alina, Deschamps, Jacqueline, Beck, Felix, Freund, Jean-Noël, Duluc, Isabelle
Published in The Journal of experimental medicine (05.03.2018)
Published in The Journal of experimental medicine (05.03.2018)
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Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL
Passet, Marie, Kim, Rathana, Gachet, Stéphanie, Sigaux, François, Chaumeil, Julie, Galland, Ava, Sexton, Thomas, Quentin, Samuel, Hernandez, Lucie, Larcher, Lise, Bergugnat, Hugo, Ye, Tao, Karasu, Nezih, Caye, Aurélie, Heizmann, Beate, Duluc, Isabelle, Chevallier, Patrice, Rousselot, Philippe, Huguet, Françoise, Leguay, Thibaut, Hunault, Mathilde, Pflumio, Françoise, Freund, Jean-Noël, Lobry, Camille, Lhéritier, Véronique, Dombret, Hervé, Domon-Dell, Claire, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle
Published in Blood (16.06.2022)
Published in Blood (16.06.2022)
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The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms
Beck, Marine, Baranger, Mathilde, Moufok-Sadoun, Ahlam, Bersuder, Emilie, Hinkel, Isabelle, Mellitzer, Georg, Martin, Elisabeth, Marisa, Laetitia, Duluc, Isabelle, de Reynies, Aurelien, Gaiddon, Christian, Freund, Jean-Noel, Gross, Isabelle
Published in Oncogene (21.01.2021)
Published in Oncogene (21.01.2021)
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Journal Article
Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos
Young, Teddy, Rowland, Jennifer Elizabeth, van de Ven, Cesca, Bialecka, Monika, Novoa, Ana, Carapuco, Marta, van Nes, Johan, de Graaff, Wim, Duluc, Isabelle, Freund, Jean-Noël, Beck, Felix, Mallo, Moises, Deschamps, Jacqueline
Published in Developmental cell (01.10.2009)
Published in Developmental cell (01.10.2009)
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Journal Article
A Core Response to the CDX2 Homeoprotein During Development and in Pathologies
Gourain, Victor, Duluc, Isabelle, Domon-Dell, Claire, Freund, Jean-Noël
Published in Frontiers in genetics (25.10.2021)
Published in Frontiers in genetics (25.10.2021)
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Journal Article
CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer
Delhorme, Jean-Baptiste, Bersuder, Emilie, Terciolo, Chloé, Vlami, Ourania, Chenard, Marie-Pierrette, Martin, Elisabeth, Rohr, Serge, Brigand, Cécile, Duluc, Isabelle, Freund, Jean-Noël, Gross, Isabelle
Published in Biomedicine & pharmacotherapy (01.03.2022)
Published in Biomedicine & pharmacotherapy (01.03.2022)
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Journal Article
SOX9 Is an Intestine Crypt Transcription Factor, Is Regulated by the Wnt Pathway, and Represses the CDX2 and MUC2 Genes
Blache, Philippe, van de Wetering, Marc, Duluc, Isabelle, Domon, Claire, Berta, Philippe, Freund, Jean-Noël, Clevers, Hans, Jay, Philippe
Published in The Journal of cell biology (05.07.2004)
Published in The Journal of cell biology (05.07.2004)
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Journal Article
Cdx2 determines the fate of postnatal intestinal endoderm
Stringer, Emma J, Duluc, Isabelle, Saandi, Thoueiba, Davidson, Irwin, Bialecka, Monika, Sato, Toshiro, Barker, Nick, Clevers, Hans, Pritchard, Catrin A, Winton, Doug J, Wright, Nicholas A, Freund, Jean-Noel, Deschamps, Jacqueline, Beck, Felix
Published in Development (Cambridge) (01.02.2012)
Published in Development (Cambridge) (01.02.2012)
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Journal Article
CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition
Galland, Ava, Gourain, Victor, Habbas, Karima, Güler, Yonca, Martin, Elisabeth, Ebel, Claudine, Tavian, Manuela, Vallat, Laurent, Chenard, Marie‐Pierre, Mauvieux, Laurent, Freund, Jean‐Noël, Duluc, Isabelle, Domon‐Dell, Claire
Published in Molecular oncology (01.09.2021)
Published in Molecular oncology (01.09.2021)
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Journal Article
Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing
Balbinot, Camille, Vanier, Marie, Armant, Olivier, Nair, Asmaa, Penichon, Julien, Soret, Christine, Martin, Elisabeth, Saandi, Thoueiba, Reimund, Jean-Marie, Deschamps, Jacqueline, Beck, Felix, Domon-Dell, Claire, Gross, Isabelle, Duluc, Isabelle, Freund, Jean-Noël
Published in Cell death and differentiation (01.12.2017)
Published in Cell death and differentiation (01.12.2017)
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Journal Article
Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene
Benahmed, Fairouz, Gross, Isabelle, Gaunt, Stephen J, Beck, Felix, Jehan, Frédéric, Domon-Dell, Claire, Martin, Elisabeth, Kedinger, Michèle, Freund, Jean-Noël, Duluc, Isabelle
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2008)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2008)
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Journal Article
TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3
Martianov, Igor, Cler, Emilie, Duluc, Isabelle, Vicaire, Serge, Philipps, Muriel, Freund, Jean-Noel, Davidson, Irwin
Published in PloS one (03.02.2014)
Published in PloS one (03.02.2014)
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Journal Article
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation
GESPACH, Christian, GROSS, Isabelle, LHERMITTE, Benoit, DOMON-DELL, Claire, DULUC, Isabelle, MARTIN, Elisabeth, GAIDDON, Christian, KEDINGER, Michele, FREUND, Jean-Noël
Published in Oncogene (01.12.2005)
Published in Oncogene (01.12.2005)
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Journal Article
Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix-Mediated Intestinal Cell Differentiation
Lorentz, Olivier, Duluc, Isabelle, De Arcangelis, Adèle, Simon-Assmann, Patricia, Kedinger, Michèle, Freund, Jean-Noël
Published in The Journal of cell biology (15.12.1997)
Published in The Journal of cell biology (15.12.1997)
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Journal Article
The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells
Benahmed, Fairouz, Gross, Isabelle, Guenot, Dominique, Jehan, Frédéric, Martin, Elisabeth, Domon-Dell, Claire, Brabletz, Thomas, Kedinger, Michèle, Freund, Jean-Noël, Duluc, Isabelle
Published in The American journal of pathology (01.02.2007)
Published in The American journal of pathology (01.02.2007)
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Journal Article
Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells
Duluc, I, Lorentz, O, Fritsch, C, Leberquier, C, Kedinger, M, Freund, J N
Published in Journal of cell science (01.06.1997)
Published in Journal of cell science (01.06.1997)
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Journal Article
Cdx1 homeobox gene during human colon cancer progression
DOMON-DELL, Claire, SCHNEIDER, Anne, DUCLOS, Bernard, CHENARD, Marie-Pierre, MEYER, Christian, OUDET, Pierre, KEDINGER, Michèle, GAUB, Marie-Pierre, FREUND, Jean-Noël, MOUCADEL, Virginie, GUERIN, Eric, GUENOT, Dominique, AGUILLON, Sarah, DULUC, Isabelle, MARTIN, Elisabeth, IOVANNA, Juan, LAUNAY, Jean-Francois
Published in Oncogene (11.09.2003)
Published in Oncogene (11.09.2003)
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