Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning
Auerbach, Scott S., Shah, Ruchir R., Mav, Deepak, Smith, Cynthia S., Walker, Nigel J., Vallant, Molly K., Boorman, Gary A., Irwin, Richard D.
Published in Toxicology and applied pharmacology (15.03.2010)
Published in Toxicology and applied pharmacology (15.03.2010)
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Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects
Heinloth, Alexandra N., Irwin, Richard D., Boorman, Gary A., Nettesheim, Paul, Fannin, Rickie D., Sieber, Stella O., Snell, Michael L., Tucker, Charles J., Li, Leping, Travlos, Gregory S., Vansant, Gordon, Blackshear, Pamela E., Tennant, Raymond W., Cunningham, Michael L., Paules, Richard S.
Published in Toxicological sciences (01.07.2004)
Published in Toxicological sciences (01.07.2004)
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Testing an Aflatoxin B1 Gene Signature in Rat Archival Tissues
Merrick, B. Alex, Auerbach, Scott S, Stockton, Patricia S, Foley, Julie F, Malarkey, David E, Sills, Robert C, Irwin, Richard D, Tice, Raymond R
Published in Chemical research in toxicology (21.05.2012)
Published in Chemical research in toxicology (21.05.2012)
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Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland
Zheng, Changyu, Goldsmith, Corinne M, Mineshiba, Fumi, Chiorini, John A, Kerr, Andrew, Wenk, Martin L, Vallant, Molly, Irwin, Richard D, Baum, Bruce J
Published in Human gene therapy (01.11.2006)
Published in Human gene therapy (01.11.2006)
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Hepatic Gene Expression Changes throughout the Day in the Fischer Rat: Implications for Toxicogenomic Experiments
Boorman, Gary A., Blackshear, Pamela E., Parker, Joel S., Lobenhofer, Edward K., Malarkey, David E., Vallant, Molly K., Gerken, Diane K., Irwin, Richard D.
Published in Toxicological sciences (01.07.2005)
Published in Toxicological sciences (01.07.2005)
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Gene interaction network analysis suggests differences between high and low doses of acetaminophen
Toyoshiba, Hiroyoshi, Sone, Hideko, Yamanaka, Takeharu, Parham, Frederick M., Irwin, Richard D., Boorman, Gary A., Portier, Christopher J.
Published in Toxicology and applied pharmacology (15.09.2006)
Published in Toxicology and applied pharmacology (15.09.2006)
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A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein
Auerbach, Scott S, Mahler, Joel, Travlos, Gregory S, Irwin, Richard D
Published in Toxicology (Amsterdam) (20.11.2008)
Published in Toxicology (Amsterdam) (20.11.2008)
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Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype
Lobenhofer, Edward K, Auman, J Todd, Blackshear, Pamela E, Boorman, Gary A, Bushel, Pierre R, Cunningham, Michael L, Fostel, Jennifer M, Gerrish, Kevin, Heinloth, Alexandra N, Irwin, Richard D, Malarkey, David E, Merrick, B Alex, Sieber, Stella O, Tucker, Charles J, Ward, Sandra M, Wilson, Ralph E, Hurban, Patrick, Tennant, Raymond W, Paules, Richard S
Published in Genome biology (20.06.2008)
Published in Genome biology (20.06.2008)
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Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands
Zheng, Changyu, Voutetakis, Antonis, Goldstein, Benjamin, Afione, Sandra, Rivera, Victor M, Clackson, Tim, Wenk, Martin L, Boyle, Molly, Nyska, Abraham, Chiorini, John A, Vallant, Molly, Irwin, Richard D, Baum, Bruce J
Published in Toxicological sciences (01.09.2011)
Published in Toxicological sciences (01.09.2011)
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Hepatic transcript levels for genes coding for enzymes associated with xenobiotic metabolism are altered with age
Mori, Kazuhiko, Blackshear, Pamela E, Lobenhofer, Edward K, Parker, Joel S, Orzech, Denise P, Roycroft, Joseph H, Walker, Kimwa L, Johnson, Kennita A, Marsh, Tiwanda A, Irwin, Richard D, Boorman, Gary A
Published in Toxicologic pathology (01.02.2007)
Published in Toxicologic pathology (01.02.2007)
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Influence of Functional Group Substitutions on the Carcinogenicity of Anthraquinone in Rats and Mice: Analysis of Long-Term Bioassays by the National Cancer Institute and the National Toxicology Program
Doi, Adriana M., Irwin, Richard D., Bucher, John R.
Published in Journal of toxicology and environmental health. Part B, Critical reviews (01.03.2005)
Published in Journal of toxicology and environmental health. Part B, Critical reviews (01.03.2005)
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Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen
Irwin, Richard D, Parker, Joel S, Lobenhofer, Edward K, Burka, Leo T, Blackshear, Pamela E, Vallant, Molly K, Lebetkin, Edward H, Gerken, Diane F, Boorman, Gary A
Published in Toxicologic pathology (2005)
Published in Toxicologic pathology (2005)
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Variation in the hepatic gene expression in individual male Fischer rats
Boorman, Gary A, Irwin, Richard D, Vallant, Molly K, Gerken, Diane K, Lobenhofer, Edward K, Hejtmancik, Milton R, Hurban, Patrick, Brys, April M, Travlos, Greg S, Parker, Joel S, Portier, Christopher J
Published in Toxicologic pathology (2005)
Published in Toxicologic pathology (2005)
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Carcinogenicity of Glycidol in F344 Rats and B6C3F1 Mice
Irwin, Richard D., Eustis, Scot L., Stefanski, Steven, Haseman, Joseph K.
Published in Journal of applied toxicology (01.05.1996)
Published in Journal of applied toxicology (01.05.1996)
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Cross-linking of neurofilament proteins of rat spinal cord in vivo after administration of 2,5-hexanedione
Lapadula, D M, Irwin, R D, Suwita, E, Abou-Donia, M B
Published in Journal of neurochemistry (01.06.1986)
Published in Journal of neurochemistry (01.06.1986)
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