SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
Hu, Jian, Li, Xiangjie, Coleman, Kyle, Schroeder, Amelia, Ma, Nan, Irwin, David J., Lee, Edward B., Shinohara, Russell T., Li, Mingyao
Published in Nature methods (01.11.2021)
Published in Nature methods (01.11.2021)
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Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders
Olsson, Bob, Portelius, Erik, Cullen, Nicholas C, Sandelius, Åsa, Zetterberg, Henrik, Andreasson, Ulf, Höglund, Kina, Irwin, David J, Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David, McCluskey, Leo, Elman, Lauren, Shaw, Leslie M, Toledo, Jon B, McBride, Jennifer, Hernandez-Con, Pilar, Lee, Virginia M-Y, Trojanowski, John Q, Blennow, Kaj
Published in Archives of neurology (Chicago) (01.03.2019)
Published in Archives of neurology (Chicago) (01.03.2019)
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Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
Irwin, David J, Dr, Grossman, Murray, MD, Weintraub, Daniel, MD, Hurtig, Howard I, MD, Duda, John E, MD, Xie, Sharon X, PhD, Lee, Edward B, MD, Van Deerlin, Vivianna M, MD, Lopez, Oscar L, MD, Kofler, Julia K, MD, Nelson, Peter T, MD, Jicha, Gregory A, MD, Woltjer, Randy, MD, Quinn, Joseph F, MD, Kaye, Jeffery, MD, Leverenz, James B, MD, Tsuang, Debby, MD, Longfellow, Katelan, MD, Yearout, Dora, BS, Kukull, Walter, PhD, Keene, C Dirk, MD, Montine, Thomas J, MD, Zabetian, Cyrus P, MD, Trojanowski, John Q, MD
Published in Lancet neurology (01.01.2017)
Published in Lancet neurology (01.01.2017)
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Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
Brettschneider, Johannes, Del Tredici, Kelly, Toledo, Jon B., Robinson, John L., Irwin, David J., Grossman, Murray, Suh, EunRan, Van Deerlin, Vivianna M., Wood, Elisabeth M., Baek, Young, Kwong, Linda, Lee, Edward B., Elman, Lauren, McCluskey, Leo, Fang, Lubin, Feldengut, Simone, Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Published in Annals of neurology (01.07.2013)
Published in Annals of neurology (01.07.2013)
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Neuropathologic substrates of Parkinson disease dementia
Irwin, David J., White, Matthew T., Toledo, Jon B., Xie, Sharon X., Robinson, John L., Van Deerlin, Vivianna, Lee, Virginia M.-Y., Leverenz, James B., Montine, Thomas J., Duda, John E., Hurtig, Howard I., Trojanowski, John Q.
Published in Annals of neurology (01.10.2012)
Published in Annals of neurology (01.10.2012)
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Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau
Darwich, Nabil F, Phan, Jessica M, Kim, Boram, Suh, EunRan, Papatriantafyllou, John D, Changolkar, Lakshmi, Nguyen, Aivi T, O'Rourke, Caroline M, He, Zhuohao, Porta, Sílvia, Gibbons, Garrett S, Luk, Kelvin C, Papageorgiou, Sokratis G, Grossman, Murray, Massimo, Lauren, Irwin, David J, McMillan, Corey T, Nasrallah, Ilya M, Toro, Camilo, Aguirre, Geoffrey K, Van Deerlin, Vivianna M, Lee, Edward B
Published in Science (American Association for the Advancement of Science) (20.11.2020)
Published in Science (American Association for the Advancement of Science) (20.11.2020)
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Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology
Portelius, Erik, Olsson, Bob, Höglund, Kina, Cullen, Nicholas C., Kvartsberg, Hlin, Andreasson, Ulf, Zetterberg, Henrik, Sandelius, Åsa, Shaw, Leslie M., Lee, Virginia M. Y., Irwin, David J., Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo, Elman, Lauren, McBride, Jennifer, Toledo, Jon B., Trojanowski, John Q., Blennow, Kaj
Published in Acta neuropathologica (01.09.2018)
Published in Acta neuropathologica (01.09.2018)
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C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD
Liu, Elaine Y., Russ, Jenny, Wu, Kathryn, Neal, Donald, Suh, Eunran, McNally, Anna G., Irwin, David J., Van Deerlin, Vivianna M., Lee, Edward B.
Published in Acta neuropathologica (01.10.2014)
Published in Acta neuropathologica (01.10.2014)
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Deep clinical and neuropathological phenotyping of Pick disease
Irwin, David J., Brettschneider, Johannes, McMillan, Corey T., Cooper, Felicia, Olm, Christopher, Arnold, Steven E., Van Deerlin, Vivianna M., Seeley, William W., Miller, Bruce L., Lee, Edward B., Lee, Virginia M.-Y., Grossman, Murray, Trojanowski, John Q.
Published in Annals of neurology (01.02.2016)
Published in Annals of neurology (01.02.2016)
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Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)
Brettschneider, Johannes, Del Tredici, Kelly, Irwin, David J., Grossman, Murray, Robinson, John L., Toledo, Jon B., Fang, Lubin, Van Deerlin, Vivianna M., Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Published in Acta neuropathologica (01.03.2014)
Published in Acta neuropathologica (01.03.2014)
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Emerging Diagnostic and Therapeutic Strategies for Tauopathies
Coughlin, David, Irwin, David J.
Published in Current neurology and neuroscience reports (01.09.2017)
Published in Current neurology and neuroscience reports (01.09.2017)
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An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline
Trzeciakiewicz, Hanna, Ajit, Deepa, Tseng, Jui-Heng, Chen, Youjun, Ajit, Aditi, Tabassum, Zarin, Lobrovich, Rebecca, Peterson, Claire, Riddick, Natallia V., Itano, Michelle S., Tripathy, Ashutosh, Moy, Sheryl S., Lee, Virginia M. Y., Trojanowski, John Q., Irwin, David J., Cohen, Todd J.
Published in Nature communications (02.11.2020)
Published in Nature communications (02.11.2020)
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Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia
Giannini, Lucia A A, Irwin, David J, McMillan, Corey T, Ash, Sharon, Rascovsky, Katya, Wolk, David A, Van Deerlin, Vivianna M, Lee, Edward B, Trojanowski, John Q, Grossman, Murray
Published in Neurology (13.06.2017)
Published in Neurology (13.06.2017)
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Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
IRWIN, David J, COHEN, Todd J, GROSSMAN, Murray, ARNOLD, Steven E, XIE, Sharon X, LEE, Virginia M.-Y, TROJANOWSKI, John Q
Published in Brain (London, England : 1878) (01.03.2012)
Published in Brain (London, England : 1878) (01.03.2012)
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TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
Brettschneider, Johannes, Arai, Kimihito, Del Tredici, Kelly, Toledo, Jon B., Robinson, John L., Lee, Edward B., Kuwabara, Satoshi, Shibuya, Kazumoto, Irwin, David J., Fang, Lubin, Van Deerlin, Vivianna M., Elman, Lauren, McCluskey, Leo, Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Published in Acta neuropathologica (01.09.2014)
Published in Acta neuropathologica (01.09.2014)
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The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease
Gourmaud, Sarah, Stewart, David A, Irwin, David J, Roberts, Nicholas, Barbour, Aaron J, Eberwine, Grace, O'Brien, William T, Vassar, Robert, Talos, Delia M, Jensen, Frances E
Published in Brain (London, England : 1878) (29.03.2022)
Published in Brain (London, England : 1878) (29.03.2022)
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Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders
Coughlin, David, Xie, Sharon X., Liang, Mendy, Williams, Andrew, Peterson, Claire, Weintraub, Daniel, McMillan, Corey T., Wolk, David A., Akhtar, Rizwan S., Hurtig, Howard I., Branch Coslett, H., Hamilton, Roy H., Siderowf, Andrew D., Duda, John E., Rascovsky, Katya, Lee, Edward B., Lee, Virginia M.‐Y., Grossman, Murray, Trojanowski, John Q., Irwin, David J.
Published in Annals of neurology (01.02.2019)
Published in Annals of neurology (01.02.2019)
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Differentiating primary progressive aphasias in a brief sample of connected speech
Ash, Sharon, Evans, Emily, O'Shea, Jessica, Powers, John, Boller, Ashley, Weinberg, Danielle, Haley, Jenna, McMillan, Corey, Irwin, David J, Rascovsky, Katya, Grossman, Murray
Published in Neurology (23.07.2013)
Published in Neurology (23.07.2013)
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