Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability
Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schettino, Giuseppe, Salto-Tellez, Manuel, Boultwood, Jacqueline, Richard, Derek J., McDade, Simon S., Harkin, D. Paul
Published in Molecular cell (08.05.2014)
Published in Molecular cell (08.05.2014)
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Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer
Bankhead, Peter, Fernández, José A, McArt, Darragh G, Boyle, David P, Li, Gerald, Loughrey, Maurice B, Irwin, Gareth W, Harkin, D Paul, James, Jacqueline A, McQuaid, Stephen, Salto-Tellez, Manuel, Hamilton, Peter W
Published in Laboratory investigation (01.01.2018)
Published in Laboratory investigation (01.01.2018)
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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
SAVAGE, Kienan I, MATCHETT, Kyle B, POWELL, Alexander, MANTI, Lorenzo, MCDADE, Simon S, BEN HO PARK, PRISE, Kevin M, MCINTOSH, Stuart A, SALTO-TELLEZ, Manuel, RICHARD, Derek J, ELLIOTT, Christopher T, HARKIN, D. Paul, BARROS, Eliana M, COOPER, Kevin M, IRWIN, Gareth W, GORSKI, Julia J, ORR, Katy S, VOHHODINA, Jekaterina, KAVANAGH, Joy N, MADDEN, Angelina F
Published in Cancer research (Chicago, Ill.) (15.05.2014)
Published in Cancer research (Chicago, Ill.) (15.05.2014)
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Erythropoietin drives breast cancer progression by activation of its receptor EPOR
Chan, Ka Kui, Matchett, Kyle B, Coulter, Jonathan A, Yuen, Hiu-Fung, McCrudden, Cian M, Zhang, Shu-Dong, Irwin, Gareth W, Davidson, Matthew A, Rülicke, Thomas, Schober, Sophie, Hengst, Ludger, Jaekel, Heidelinde, Platt-Higgins, Angela, Rudland, Philip S, Mills, Ken I, Maxwell, Perry, El-Tanani, Mohamed, Lappin, Terence R
Published in Oncotarget (13.06.2017)
Published in Oncotarget (13.06.2017)
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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
Lappin, Katrina M, Barros, Eliana M, Jhujh, Satpal S, Irwin, Gareth W, McMillan, Hayley, Liberante, Fabio G, Latimer, Cheryl, La Bonte, Melissa J, Mills, Ken I, Harkin, D Paul, Stewart, Grant S, Savage, Kienan I
Published in Cancer research (Chicago, Ill.) (01.03.2022)
Published in Cancer research (Chicago, Ill.) (01.03.2022)
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Corrigendum to: Current practice and surgical outcomes of neoadjuvant chemotherapy for early breast cancer: UK NeST study
Fatayer, Hiba, O'Connell, Rachel L, Bannon, Finian, Coles, Charlotte E, Copson, Ellen, Cutress, Ramsey I, Dave, Rajiv V, Gardiner, Matthew D, Grayson, Margaret, Holcombe, Christopher, Irshad, Sheeba, Irwin, Gareth W, O'Brien, Ciara, Palmieri, Carlo, Shaaban, Abeer M, Sharma, Nisha, Singh, Jagdeep K, Whitehead, Ian, Potter, Shelley, McIntosh, Stuart A
Published in British journal of surgery (13.12.2022)
Published in British journal of surgery (13.12.2022)
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Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer
O’Rorke, Michael, Irwin, Gareth W., Kennedy, Richard D., Mullan, Paul B., McQuaid, Stephen, Salto-Tellez, Manuel, Buckley, Niamh E., Blayney, Jaine K., Parkes, Eileen E., Patel-Socha, Farah, James, Jacqueline, Cougot, Delphine, Bingham, Victoria, Hynes, Sean, Humphries, Matthew P., McArt, Darragh G.
Published in Journal of oncology (01.01.2018)
Published in Journal of oncology (01.01.2018)
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Negative Pressure Wound Therapy Reduces Wound Breakdown and Implant Loss in Prepectoral Breast Reconstruction
Irwin, Gareth W., Boundouki, George, Fakim, Bilal, Johnson, Richard, Highton, Lyndsey, Myers, Dave, Searle, Richard, Murphy, John A.
Published in Plastic and reconstructive surgery. Global open (01.02.2020)
Published in Plastic and reconstructive surgery. Global open (01.02.2020)
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TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities
D'Costa, Zenobia C, Higgins, Catherine, Ong, Chee Wee, Irwin, Gareth W, Boyle, David, McArt, Darragh G, McCloskey, Karen, Buckley, Niamh E, Crawford, Nyree T, Thiagarajan, Lalitha, Murray, James T, Kennedy, Richard D, Mulligan, Karl A, Harkin, D Paul, Waugh, David J J, Scott, Chris J, Salto-Tellez, Manuel, Williams, Richard, Mullan, Paul B
Published in Oncotarget (30.03.2014)
Published in Oncotarget (30.03.2014)
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PICan: An integromics framework for dynamic cancer biomarker discovery
McArt, Darragh G., Blayney, Jaine K., Boyle, David P., Irwin, Gareth W., Moran, Michael, Hutchinson, Ryan A., Bankhead, Peter, Kieran, Declan, Wang, Yinhai, Dunne, Philip D., Kennedy, Richard D., Mullan, Paul B., Harkin, D. Paul, Catherwood, Mark A., James, Jacqueline A., Salto-Tellez, Manuel, Hamilton, Peter W.
Published in Molecular oncology (01.06.2015)
Published in Molecular oncology (01.06.2015)
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The molecular and genetic basis of inherited cancer risk in gynaecology
Beirne, James P, Irwin, Gareth W, McIntosh, Stuart A, Harley, Ian JG, Harkin, D Paul
Published in The obstetrician & gynaecologist (01.10.2015)
Published in The obstetrician & gynaecologist (01.10.2015)
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Academic medicine - revolution, evolution or extinction?
Irwin, Gareth W, Spence, Roy A J, McAuley, Danny F, Kennedy, Richard D, Gardiner, Keith R, Elborn, J Stuart
Published in The Ulster medical journal (01.09.2014)
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Published in The Ulster medical journal (01.09.2014)
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Abstract P2-16-04: National utilisation of neoadjuvant systemic therapy and impact on surgical treatment - A prospective multi-centre cohort study
McIntosh, Stuart A, Irwin, Gareth W, Bannon, Finian, Coles, Charlotte, Copson, Ellen, Cutress, Ramsey, Dave, Rajiv, Grayson, Margaret, Holcombe, Chris, Irshad, Sheeba, O'Brien, Ciara, O'Connell, Rachel, Palmieri, Carlo, Shaaban, Abeer M, Sharma, Nisha, Singh, Jagdeep, Whitehead, Ian, Potter, Shelley
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Current practice and surgical outcomes of neoadjuvant chemotherapy for early breast cancer: UK NeST study
Fatayer, Hiba, O’Connell, Rachel L, Bannon, Finian, Coles, Charlotte E, Copson, Ellen, Cutress, Ramsey I, Dave, Rajiv V, Gardiner, Matthew D, Grayson, Margaret, Holcombe, Christopher, Irshad, Sheeba, Irwin, Gareth W, O’Brien, Ciara, Palmieri, Carlo, Shaaban, Abeer M, Sharma, Nisha, Singh, Jagdeep K, Whitehead, Ian, Potter, Shelley, McIntosh, Stuart A
Published in British journal of surgery (16.08.2022)
Published in British journal of surgery (16.08.2022)
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