Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and β‑Thalassemia Mice
Lisk, Christina, Cendali, Francesca, Setua, Saini, Thangaraju, Kiruphararan, Pak, David I., Swindle, Delaney, Dzieciatkowska, Monika, Gamboni, Fabia, Hassell, Kathryn, Nuss, Rachelle, George, Gemlyn, Davizon-Castillo, Pavel, Buehler, Paul W., D’Alessandro, Angelo, Irwin, David C.
Published in Journal of proteome research (01.09.2023)
Published in Journal of proteome research (01.09.2023)
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Magnetophoretic and spectral characterization of oxyhemoglobin and deoxyhemoglobin: Chemical versus enzymatic processes
Weigand, Mitchell R. H, Gómez-Pastora, Jenifer, Kim, James, Kurek, Matthew T, Hickey, Richard J, Irwin, David C, Buehler, Paul W, Zborowski, Maciej, Palmer, Andre F, Chalmers, Jeffrey J
Published in PloS one (03.09.2021)
Published in PloS one (03.09.2021)
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Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism
Lisk, Christina, Kominsky, Doug, Ehrentraut, Stefan, Bonaventura, Joe, Nuss, Rachelle, Hassell, Kathryn, Nozik-Grayck, Eva, Irwin, David C
Published in American journal of respiratory cell and molecular biology (01.10.2013)
Published in American journal of respiratory cell and molecular biology (01.10.2013)
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Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation
Loomis, Zoe, Eigenberger, Paul, Redinius, Katherine, Lisk, Christina, Karoor, Vijaya, Nozik-Grayck, Eva, Ferguson, Scott K, Hassell, Kathryn, Nuss, Rachelle, Stenmark, Kurt, Buehler, Paul, Irwin, David C
Published in PloS one (02.02.2017)
Published in PloS one (02.02.2017)
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Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension
Lemon, Douglas D, Horn, Todd R, Cavasin, Maria A, Jeong, Mark Y, Haubold, Kurt W, Long, Carlin S, Irwin, David C, McCune, Sylvia A, Chung, Eunhee, Leinwand, Leslie A, McKinsey, Timothy A
Published in Journal of molecular and cellular cardiology (01.07.2011)
Published in Journal of molecular and cellular cardiology (01.07.2011)
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Agonistic Anti-CD40 Antibody Triggers an Acute Liver Crisis With Systemic Inflammation in Humanized Sickle Cell Disease Mice
Yalamanoglu, Ayla, Dubach, Irina L, Schulthess, Nadja, Ingoglia, Giada, Swindle, Delaney C, Humar, Rok, Schaer, Dominik J, Buehler, Paul W, Irwin, David C, Vallelian, Florence
Published in Frontiers in immunology (04.03.2021)
Published in Frontiers in immunology (04.03.2021)
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Peritoneal Infusion of Oxygen Microbubbles Alters the Metabolomic Profile of the Lung and Spleen in Acute Hypoxic Exposure
Lisk, Christina, Fan, Alex, Cendali, Francesca I, Kakiuchi, Kenta, Swindle, Delaney, Pak, David I, Tolson, Robert, Grier, Abby, Buesing, Keely, Zaeske, Seth, D’Alessandro, Angelo, Borden, Mark A, Irwin, David C
Published in Bioengineering (Basel) (01.08.2024)
Published in Bioengineering (Basel) (01.08.2024)
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Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease
Thangaraju, Kiruphagaran, Setua, Saini, Lisk, Christina, Swindle, Delaney, Stephenson, Daniel, Dzieciatkowska, Monika, Lamb, Derek R., Moitra, Parikshit, Pak, David, Hassell, Kathryn, George, Gemlyn, Nuss, Rachelle, Davizon-Castillo, Pavel, Stenmark, Kurt R., D’Alessandro, Angelo, Irwin, David C., Buehler, Paul W.
Published in Clinical and applied thrombosis/hemostasis (01.01.2023)
Published in Clinical and applied thrombosis/hemostasis (01.01.2023)
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Moderate hypoxia induces metabolic divergence in circulating monocytes and tissue resident macrophages from Berkeley sickle cell anemia mice
Lisk, Christina, Cendali, Francesca, Pak, David I, Swindle, Delaney, Hassell, Kathryn, Nuss, Rachelle, George, Gemlyn, Davizon-Castillo, Pavel, Buehler, Paul W, D'Alessandro, Angelo, Irwin, David C
Published in Frontiers in medicine (12.07.2023)
Published in Frontiers in medicine (12.07.2023)
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Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features
Buehler, Paul W., Swindle, Delaney, Pak, David I., Fini, Mehdi A., Hassell, Kathryn, Nuss, Rachelle, Wilkerson, Rebecca B., D’Alessandro, Angelo, Irwin, David C.
Published in Pulmonary circulation (01.10.2021)
Published in Pulmonary circulation (01.10.2021)
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Metabolite G-Protein Coupled Receptors in Cardio-Metabolic Diseases
Strassheim, Derek, Sullivan, Timothy, Irwin, David C, Gerasimovskaya, Evgenia, Lahm, Tim, Klemm, Dwight J, Dempsey, Edward C, Stenmark, Kurt R, Karoor, Vijaya
Published in Cells (Basel, Switzerland) (29.11.2021)
Published in Cells (Basel, Switzerland) (29.11.2021)
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Correction: Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation
Loomis, Zoe, Eigenberger, Paul, Redinius, Katherine, Lisk, Christina, Karoor, Vijaya, Nozik-Grayck, Eva, Ferguson, Scott K, Hassell, Kathryn, Nuss, Rachelle, Stenmark, Kurt R, Buehler, Paul W, Irwin, David C
Published in PloS one (06.03.2017)
Published in PloS one (06.03.2017)
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Pre-clinical assessment of a water-in-fluorocarbon emulsion for the treatment of pulmonary vascular diseases
Ferguson, Scott K., Pak, David I., Hopkins, Justin L., Harral, Julie W., Redinius, Katherine M., Loomis, Zoe, Stenmark, Kurt R., Borden, Mark A., Schroeder, Thies, Irwin, David C.
Published in Drug delivery (01.01.2019)
Published in Drug delivery (01.01.2019)
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"Omics" data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy
Campbell, Nzali V, Weitzenkamp, David A, Campbell, Ian L, Schmidt, Ronald F, Hicks, Chindo, Morgan, Michael J, Irwin, David C, Tentler, John J
Published in BMC medical genomics (12.12.2018)
Published in BMC medical genomics (12.12.2018)
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Evidence supporting a role for circulating macrophages in the regression of vascular remodeling following sub-chronic exposure to hemoglobin plus hypoxia
Karoor, Vijaya, Swindle, Delaney, Pak, David I, Harral, Julie, Strassheim, Derek, Fini, Mehdi A, Dempsey, Edward, Stenmark, Kurt R, Hassell, Kathryn, Nuss, Rachelle, Buehler, Paul W., Irwin, David C.
Published in Pulmonary circulation (01.10.2021)
Published in Pulmonary circulation (01.10.2021)
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Optimization of combined measures of airway physiology and cardiovascular hemodynamics in mice
Kopf, Katrina W., Harral, Julie W., Staker, Emily A., Summers, Megan E., Petrache, Irina, Kheyfets, Vitaly, Irwin, David C., Majka, Susan M.
Published in Pulmonary circulation (01.01.2020)
Published in Pulmonary circulation (01.01.2020)
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Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis
Schaer, Christian A, Deuel, Jeremy W, Schildknecht, Daniela, Mahmoudi, Leila, Garcia-Rubio, Ines, Owczarek, Catherine, Schauer, Stefan, Kissner, Reinhard, Banerjee, Uddyalok, Palmer, Andre F, Spahn, Donat R, Irwin, David C, Vallelian, Florence, Buehler, Paul W, Schaer, Dominik J
Published in American journal of respiratory and critical care medicine (15.05.2016)
Published in American journal of respiratory and critical care medicine (15.05.2016)
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Understanding Exercise (in)tolerance in Sickle Cell Disease: Impacts of Hemolysis and Exercise Training on Skeletal Muscle Oxygen Delivery
Irwin, David C., Calvo, Edward T. N., Belbis, Michael D., Ehrenfort, Sabrina K. C., Noguer, Mathilde, Messonnier, Laurent A., Buehler, Paul W., Hirai, Daniel M., Ferguson, Scott K.
Published in Journal of applied physiology (1985) (29.08.2024)
Published in Journal of applied physiology (1985) (29.08.2024)
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Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart
Zhao, Yuanbiao, Riching, Andrew S, Knight, Walter E, Chi, Congwu, Broadwell, Lindsey J, Du, Yanmei, Abdel-Hafiz, Mostafa, Ambardekar, Amrut V, Irwin, David C, Proenza, Catherine, Xu, Hongyan, Leinwand, Leslie A, Walker, Lori A, Woulfe, Kathleen C, Bristow, Michael R, Buttrick, Peter M, Song, Kunhua
Published in Circulation (New York, N.Y.) (30.08.2022)
Published in Circulation (New York, N.Y.) (30.08.2022)
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