The AURORA initiative for metastatic breast cancer
Zardavas, D, Maetens, M, Irrthum, A, Goulioti, T, Engelen, K, Fumagalli, D, Salgado, R, Aftimos, P, Saini, K S, Sotiriou, C, Campbell, P, Dinh, P, von Minckwitz, G, Gelber, R D, Dowsett, M, Di Leo, A, Cameron, D, Baselga, J, Gnant, M, Goldhirsch, A, Norton, L, Piccart, M
Published in British journal of cancer (11.11.2014)
Published in British journal of cancer (11.11.2014)
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First report of AURORA, the breast international group (BIG) molecular screening initiative for metastatic breast cancer (MBC) patients (pts)
Aftimos, P.G., Antunes De Melo e Oliveira, A.M., Hilbers, F., Venet, D., Vingiani, A., Nili Gal Yam, E., Martinez, J.L., Ndozeng, J., Irrthum, A., Piccart, M.
Published in Annals of oncology (01.05.2019)
Published in Annals of oncology (01.05.2019)
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Journal Article
Mutations in the VEGFR3 Signaling Pathway Explain 36% of Familial Lymphedema
Mendola, A., Schlögel, M.J., Ghalamkarpour, A., Irrthum, A., Nguyen, H.L., Fastré, E., Bygum, A., van der Vleuten, C., Fagerberg, C., Baselga, E., Quere, I., Mulliken, J.B., Boon, L.M., Brouillard, P., Vikkula, M.
Published in Molecular syndromology (01.09.2013)
Published in Molecular syndromology (01.09.2013)
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Multiple mechanisms are implicated in the generation of 5q35 microdeletions in Sotos syndrome
Tatton-Brown, K, Douglas, J, Coleman, K, Baujat, G, Chandler, K, Clarke, A, Collins, A, Davies, S, Faravelli, F, Firth, H, Garrett, C, Hughes, H, Kerr, B, Liebelt, J, Reardon, W, Schaefer, G B, Splitt, M, Temple, I K, Waggoner, D, Weaver, D D, Wilson, L, Cole, T, Cormier-Daire, V, Irrthum, A, Rahman, N
Published in Journal of medical genetics (01.04.2005)
Published in Journal of medical genetics (01.04.2005)
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Partial NSD1 deletions cause 5% of Sotos syndrome and are readily identifiable by multiplex ligation dependent probe amplification
Douglas, J, Tatton-Brown, K, Coleman, K, Guerrero, S, Berg, J, Cole, T R P, FitzPatrick, D, Gillerot, Y, Hughes, H E, Pilz, D, Raymond, F L, Temple, I K, Irrthum, A, Schouten, J P, Rahman, N
Published in Journal of medical genetics (01.09.2005)
Published in Journal of medical genetics (01.09.2005)
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341MO Impact of aging on the genetic and transcriptional landscape of advanced breast cancer: an AURORA program (BIG 14-01) subanalysis
Zoppoli, G., Ravera, F., Santaniello, F., Ferrando, L., Venet, D., Seoane, J.A., Richard, F., Munzone, E., Hatse, S., Ballestrero, A., Crestani, T. Antoniolli, Adam, V.S., Irrthum, A., Aftimos, P.G., Zotano, A.L. Guerrero, Cameron, D.A., Piccart, M., Desmedt, C., Benelli, M., Wildiers, H.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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152OFirst report of AURORA, the breast international group (BIG) molecular screening initiative for metastatic breast cancer (MBC) patients (pts)
Aftimos, P G, Antunes De Melo e Oliveira, A M, Hilbers, F, Venet, D, Vingiani, A, Nili Gal Yam, E, Martinez, J L, Ndozeng, J, Irrthum, A, Piccart, M
Published in Annals of oncology (01.05.2019)
Published in Annals of oncology (01.05.2019)
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Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
Méhes, Károly, Shannon, Nora, FitzPatrick, David, Reid, Sarah, Douglas, Jenny, Firth, Helen, Plaja, Alberto, Robin, Nathanial, Irrthum, Alexandre, Nash, Richard, Tolmie, John, Kidd, Alexa, Swansbury, John, Coleman, Kim, Hanks, Sandra, Rahman, Nazneen
Published in Nature genetics (01.11.2004)
Published in Nature genetics (01.11.2004)
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Genotype-Phenotype Associations in Sotos Syndrome: An Analysis of 266 Individuals with NSD1 Aberrations
Tatton-Brown, Katrina, Douglas, Jenny, Coleman, Kim, Baujat, Geneviève, Cole, Trevor R.P., Das, Soma, Horn, Denise, Hughes, Helen E., Temple, I. Karen, Faravelli, Francesca, Waggoner, Darrel, Türkmen, Seval, Cormier-Daire, Valérie, Irrthum, Alexandre, Rahman, Nazneen
Published in American journal of human genetics (01.08.2005)
Published in American journal of human genetics (01.08.2005)
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Mutations in the Transcription Factor Gene SOX18 Underlie Recessive and Dominant Forms of Hypotrichosis-Lymphedema-Telangiectasia
Irrthum, Alexandre, Devriendt, Koenraad, Chitayat, David, Matthijs, Gert, Glade, Conrad, Steijlen, Peter M., Fryns, Jean-Pierre, Van Steensel, Maurice A. M., Vikkula, Miikka
Published in American journal of human genetics (01.06.2003)
Published in American journal of human genetics (01.06.2003)
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The Breast International Group (BIG) AURORA pilot study for molecular screening in metastatic breast cancer (MBC) patients
Maetens, M., Irrthum, A., Loibl, S., Laes, J.F., Campbell, P., Aftimos, P., Thompson, A., Cortes Castan, J., Loi, S., Sotiriou, C.
Published in Annals of oncology (01.05.2015)
Published in Annals of oncology (01.05.2015)
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Journal Article
Myelin-derived lipids modulate macrophage activity by liver X receptor activation
Bogie, Jeroen F J, Timmermans, Silke, Huynh-Thu, Vân Anh, Irrthum, Alexandre, Smeets, Hubert J M, Gustafsson, Jan-Åke, Steffensen, Knut R, Mulder, Monique, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome J A
Published in PloS one (12.09.2012)
Published in PloS one (12.09.2012)
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A Gene for Inherited Cutaneous Venous Anomalies (“Glomangiomas”) Localizes to Chromosome 1p21-22
Boon, Laurence M., Brouillard, Pascal, Irrthum, Alexandre, Karttunen, Leena, Warman, Matthew L., Rudolph, Ross, Mulliken, John B., Olsen, Bjorn R., Vikkula, Miikka
Published in American journal of human genetics (01.07.1999)
Published in American journal of human genetics (01.07.1999)
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Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC
Irrthum, A, Brouillard, P, Enjolras, O, Gibbs, N F, Eichenfield, L F, Olsen, B R, Mulliken, J B, Boon, L M, Vikkula, M
Published in European journal of human genetics : EJHG (01.01.2001)
Published in European journal of human genetics : EJHG (01.01.2001)
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