Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV‑2
Ghahremanpour, Mohammad M, Tirado-Rives, Julian, Deshmukh, Maya, Ippolito, Joseph A, Zhang, Chun-Hui, Cabeza de Vaca, Israel, Liosi, Maria-Elena, Anderson, Karen S, Jorgensen, William L
Published in ACS medicinal chemistry letters (10.12.2020)
Published in ACS medicinal chemistry letters (10.12.2020)
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Journal Article
Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV‑2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations
Zhang, Chun-Hui, Stone, Elizabeth A, Deshmukh, Maya, Ippolito, Joseph A, Ghahremanpour, Mohammad M, Tirado-Rives, Julian, Spasov, Krasimir A, Zhang, Shuo, Takeo, Yuka, Kudalkar, Shalley N, Liang, Zhuobin, Isaacs, Farren, Lindenbach, Brett, Miller, Scott J, Anderson, Karen S, Jorgensen, William L
Published in ACS central science (24.03.2021)
Published in ACS central science (24.03.2021)
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Journal Article
Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
Ippolito, Joseph A, Kanyo, Zoltan F, Wang, Deping, Franceschi, Francois J, Moore, Peter B, Steitz, Thomas A, Duffy, Erin M
Published in Journal of medicinal chemistry (26.06.2008)
Published in Journal of medicinal chemistry (26.06.2008)
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Journal Article
Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV‑2 to Low-Nanomolar Antiviral Potency
Zhang, Chun-Hui, Spasov, Krasimir A, Reilly, Raquel A, Hollander, Klarissa, Stone, Elizabeth A, Ippolito, Joseph A, Liosi, Maria-Elena, Deshmukh, Maya G, Tirado-Rives, Julian, Zhang, Shuo, Liang, Zhuobin, Miller, Scott J, Isaacs, Farren, Lindenbach, Brett D, Anderson, Karen S, Jorgensen, William L
Published in ACS medicinal chemistry letters (12.08.2021)
Published in ACS medicinal chemistry letters (12.08.2021)
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Journal Article
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
Hansen, Jeffrey L., Ippolito, Joseph A., Ban, Nenad, Nissen, Poul, Moore, Peter B., Steitz, Thomas A.
Published in Molecular cell (01.07.2002)
Published in Molecular cell (01.07.2002)
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Journal Article
Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase
Frey, Kathleen M, Bertoletti, Nicole, Chan, Albert H, Ippolito, Joseph A, Bollini, Mariela, Spasov, Krasimir A, Jorgensen, William L, Anderson, Karen S
Published in Frontiers in molecular biosciences (14.02.2022)
Published in Frontiers in molecular biosciences (14.02.2022)
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Journal Article
Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance
SKRIPKIN, Eugene, MCCONNELL, Timothy S, DEVITO, Joseph, LAWRENCE, Laura, IPPOLITO, Joseph A, DUFFY, Erin M, SUTCLIFFE, Joyce, FRANCESCHI, Francois
Published in Antimicrobial Agents and Chemotherapy (01.10.2008)
Published in Antimicrobial Agents and Chemotherapy (01.10.2008)
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Journal Article
The Effect of Sex on Orthopaedic Surgeon Income
Beebe, Kathleen S, Krell, Ethan S, Rynecki, Nicole D, Ippolito, Joseph A
Published in Journal of bone and joint surgery. American volume (04.09.2019)
Published in Journal of bone and joint surgery. American volume (04.09.2019)
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Journal Article
Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease
Deshmukh, Maya G., Ippolito, Joseph A., Zhang, Chun-Hui, Stone, Elizabeth A., Reilly, Raquel A., Miller, Scott J., Jorgensen, William L., Anderson, Karen S.
Published in Structure (London) (05.08.2021)
Published in Structure (London) (05.08.2021)
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Journal Article
Supplemental Bone Grafting in Giant Cell Tumor of the Extremity Reduces Nononcologic Complications
Benevenia, Joseph, Rivero, Steven M., Moore, Jeffrey, Ippolito, Joseph A., Siegerman, Daniel A., Beebe, Kathleen S., Patterson, Francis R.
Published in Clinical orthopaedics and related research (01.03.2017)
Published in Clinical orthopaedics and related research (01.03.2017)
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Journal Article
Larger stem to bone diameter ratio predicts lower cemented endoprosthesis failure
Kadkoy, Yazan, Ippolito, Joseph A., Schneider, Gregory, Thomson, Jennifer, Park, Claire, Dias, Rosamaria, Beebe, Kathleen S., Patterson, Francis R., Benevenia, Joseph
Published in Journal of surgical oncology (01.04.2024)
Published in Journal of surgical oncology (01.04.2024)
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Journal Article
A Preoperative Scale for Determining Surgical Readmission Risk After Total Knee Arthroplasty
Siracuse, Brianna L, Ippolito, Joseph A, Gibson, Peter D, Ohman-Strickland, Pamela A, Beebe, Kathleen S
Published in Journal of bone and joint surgery. American volume (01.11.2017)
Published in Journal of bone and joint surgery. American volume (01.11.2017)
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Journal Article
Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands
Liosi, Maria-Elena, Ippolito, Joseph A., Henry, Sean P., Krimmer, Stefan G., Newton, Ana S., Cutrona, Kara J., Olivarez, Rene A., Mohanty, Jyotidarsini, Schlessinger, Joseph, Jorgensen, William L.
Published in Journal of medicinal chemistry (23.06.2022)
Published in Journal of medicinal chemistry (23.06.2022)
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Journal Article
Injuries sustained during high intensity interval training: are modern fitness trends contributing to increased injury rates?
Rynecki, Nicole D, Siracuse, Brianna L, Ippolito, Joseph A, Beebe, Kathleen S
Published in The Journal of sports medicine and physical fitness (01.07.2019)
Published in The Journal of sports medicine and physical fitness (01.07.2019)
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Journal Article
Identifying Patients at Risk for Venous Thromboembolic Events After Isolated Upper Extremity Trauma: A Predictive Scale
Ippolito, Joseph A, Siracuse, Brianna L, Galloway, Joseph D, Ahmed, Irfan, Vosbikian, Michael M
Published in Orthopedics (Thorofare, N.J.) (01.11.2022)
Published in Orthopedics (Thorofare, N.J.) (01.11.2022)
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Journal Article
Nonsurgical Treatment of De Quervain Tenosynovitis: A Prospective Randomized Trial
Ippolito, Joseph A., Hauser, Spencer, Patel, Jay, Vosbikian, Michael, Ahmed, Irfan
Published in Hand (New York, N.Y.) (01.03.2020)
Published in Hand (New York, N.Y.) (01.03.2020)
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Journal Article
Hoverboards: A New Cause of Pediatric Morbidity
Siracuse, Brianna L, Ippolito, Joseph A, Gibson, Peter D, Beebe, Kathleen S
Published in Injury (01.06.2017)
Published in Injury (01.06.2017)
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Journal Article