Curcuma longa extract exerts a myorelaxant effect on the ileum and colon in a mouse experimental colitis model, independent of the anti-inflammatory effect
Aldini, Rita, Budriesi, Roberta, Roda, Giulia, Micucci, Matteo, Ioan, Pierfranco, D'Errico-Grigioni, Antonia, Sartini, Alessandro, Guidetti, Elena, Marocchi, Margherita, Cevenini, Monica, Rosini, Francesca, Montagnani, Marco, Chiarini, Alberto, Mazzella, Giuseppe
Published in PloS one (12.09.2012)
Published in PloS one (12.09.2012)
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Castanea sativa Mill. Extract Contracts Gallbladder and Relaxes Sphincter of Oddi in Guinea Pig: A Natural Approach to Biliary Tract Motility Disorders
Micucci, Matteo, Ioan, Pierfranco, Aldini, Rita, Cevenini, Monica, Alvisi, Vittorio, Ruffilli, Corrado, Chiarini, Alberto, Budriesi, Roberta
Published in Journal of medicinal food (01.07.2014)
Published in Journal of medicinal food (01.07.2014)
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Stop Fitan: antispasmodic effect of natural extract of chestnut wood in guinea pig ileum and proximal colon smooth muscle
Budriesi, Roberta, Ioan, Pierfranco, Micucci, Matteo, Micucci, Ermanno, Limongelli, Vittorio, Chiarini, Alberto
Published in Journal of medicinal food (01.10.2010)
Published in Journal of medicinal food (01.10.2010)
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Journal Article
Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue
Massi, Matteo, Ioan, Pierfranco, Budriesi, Roberta, Chiarini, Alberto, Vitali, Beatrice, Lammers, Karen M, Gionchetti, Paolo, Campieri, Massimo, Lembo, Anthony, Brigidi, Patrizia
Published in World journal of gastroenterology : WJG (07.10.2006)
Published in World journal of gastroenterology : WJG (07.10.2006)
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Journal Article
Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors
Spinelli, Domenico, Budriesi, Roberta, Cosimelli, Barbara, Severi, Elda, Micucci, Matteo, Baroni, Massimo, Fusi, Fabio, Ioan, Pierfranco, Cross, Simon, Frosini, Maria, Saponara, Simona, Matucci, Rosanna, Rosano, Camillo, Viale, Maurizio, Chiarini, Alberto, Carosati, Emanuele
Published in Molecules (Basel, Switzerland) (14.10.2014)
Published in Molecules (Basel, Switzerland) (14.10.2014)
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WB4101-Related Compounds: New, Subtype-Selective α1-Adrenoreceptor Antagonists (or Inverse Agonists?)
Pallavicini, Marco, Budriesi, Roberta, Fumagalli, Laura, Ioan, Pierfranco, Chiarini, Alberto, Bolchi, Cristiano, Ugenti, Maria Paola, Colleoni, Simona, Gobbi, Marco, Valoti, Ermanno
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Ligand Based Approach to L‑Type Calcium Channel by Imidazo[2,1‑b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity
Locatelli, Alessandra, Cosconati, Sandro, Micucci, Matteo, Leoni, Alberto, Marinelli, Luciana, Bedini, Andrea, Ioan, Pierfranco, Spampinato, Santi Mario, Novellino, Ettore, Chiarini, Alberto, Budriesi, Roberta
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Cystic Fibrosis: A New Target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines
Budriesi, Roberta, Ioan, Pierfranco, Leoni, Alberto, Pedemonte, Nicoletta, Locatelli, Alessandra, Micucci, Matteo, Chiarini, Alberto, Galietta, Luis J. V
Published in Journal of medicinal chemistry (09.06.2011)
Published in Journal of medicinal chemistry (09.06.2011)
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Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism
Carosati, Emanuele, Cosimelli, Barbara, Ioan, Pierfranco, Severi, Elda, Katneni, Kasiram, Chiu, Francis C. K, Saponara, Simona, Fusi, Fabio, Frosini, Maria, Matucci, Rosanna, Micucci, Matteo, Chiarini, Alberto, Spinelli, Domenico, Budriesi, Roberta
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Journal Article
Sweet Chestnut (Castanea sativa Mill.) Bark Extract : Cardiovascular Activity and Myocyte Protection against Oxidative Damage
Chiarini, Alberto, Micucci, Matteo, Malaguti, Marco, Budriesi, Roberta, Ioan, Pierfranco, Lenzi, Monia, Fimognari, Carmela, Gallina Toschi, Tullia, Comandini, Patrizia, Hrelia, Silvana
Published in Oxidative medicine and cellular longevity (01.01.2013)
Published in Oxidative medicine and cellular longevity (01.01.2013)
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Imidazo[2,1-b]thiazole System: A Scaffold Endowing Dihydropyridines with Selective Cardiodepressant Activity
Budriesi, Roberta, Ioan, Pierfranco, Locatelli, Alessandra, Cosconati, Sandro, Leoni, Alberto, Ugenti, Maria P, Andreani, Aldo, Di Toro, Rosanna, Bedini, Andrea, Spampinato, Santi, Marinelli, Luciana, Novellino, Ettore, Chiarini, Alberto
Published in Journal of medicinal chemistry (27.03.2008)
Published in Journal of medicinal chemistry (27.03.2008)
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Synthesis and L-type calcium channel blocking activity of new chiral oxadiazolothiazinones
Carosati, Emanuele, Ioan, Pierfranco, Barrano, Giovanni Battista, Caccamese, Salvatore, Cosimelli, Barbara, Devlin, Frank J., Severi, Elda, Spinelli, Domenico, Superchi, Stefano, Budriesi, Roberta
Published in European journal of medicinal chemistry (06.03.2015)
Published in European journal of medicinal chemistry (06.03.2015)
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Journal Article
Novel, Potent, and Selective Quinoxaline-Based 5-HT3 Receptor Ligands. 1. Further Structure−Activity Relationships and Pharmacological Characterization
Butini, Stefania, Budriesi, Roberta, Hamon, Michel, Morelli, Elena, Gemma, Sandra, Brindisi, Margherita, Borrelli, Giuseppe, Novellino, Ettore, Fiorini, Isabella, Ioan, Pierfranco, Chiarini, Alberto, Cagnotto, Alfredo, Mennini, Tiziana, Fracasso, Claudia, Caccia, Silvio, Campiani, Giuseppe
Published in Journal of medicinal chemistry (12.11.2009)
Published in Journal of medicinal chemistry (12.11.2009)
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Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation
Tasso, Bruno, Budriesi, Roberta, Vazzana, Iana, Ioan, Pierfranco, Micucci, Matteo, Novelli, Federica, Tonelli, Michele, Sparatore, Anna, Chiarini, Alberto, Sparatore, Fabio
Published in Journal of medicinal chemistry (24.06.2010)
Published in Journal of medicinal chemistry (24.06.2010)
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Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects
Ioan, Pierfranco, Ciogli, Alessia, Sirci, Francesco, Budriesi, Roberta, Cosimelli, Barbara, Pierini, Marco, Severi, Elda, Chiarini, Alberto, Cruciani, Gabriele, Gasparrini, Francesco, Spinelli, Domenico, Carosati, Emanuele
Published in Organic & biomolecular chemistry (07.12.2012)
Published in Organic & biomolecular chemistry (07.12.2012)
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Journal Article
Calcium Channel Antagonists Discovered by a Multidisciplinary Approach
Carosati, Emanuele, Cruciani, Gabriele, Chiarini, Alberto, Budriesi, Roberta, Ioan, Pierfranco, Spisani, Raffaella, Spinelli, Domenico, Cosimelli, Barbara, Fusi, Fabio, Frosini, Maria, Matucci, Rosanna, Gasparrini, Francesco, Ciogli, Alessia, Stephens, Philip J, Devlin, Frank J
Published in Journal of medicinal chemistry (24.08.2006)
Published in Journal of medicinal chemistry (24.08.2006)
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Journal Article
Preliminary Finding on a New Calcium Channel Entry Blocker Chemotype: 5,6-Diamino-4-hydroxy-2-mercaptopyrimidine Derivatives
Cosimelli, Barbara, Severi, Elda, Novellino, Ettore, Cavaccini, Anna, Cataldi, Mauro, Budriesi, Roberta, Micucci, Matteo, Chiarini, Alberto, Ioan, Pierfranco
Published in Journal of medicinal chemistry (11.08.2011)
Published in Journal of medicinal chemistry (11.08.2011)
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Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis
Viale, Maurizio, Cordazzo, Cinzia, de Totero, Daniela, Budriesi, Roberta, Rosano, Camillo, Leoni, Alberto, Ioan, Pierfranco, Aiello, Cinzia, Croce, Michela, Andreani, Aldo, Rambaldi, Mirella, Russo, Patrizia, Chiarini, Alberto, Spinelli, Domenico
Published in Investigational new drugs (01.02.2011)
Published in Investigational new drugs (01.02.2011)
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Specific Targeting of Peripheral Serotonin 5-HT3 Receptors. Synthesis, Biological Investigation, and Structure−Activity Relationships
Morelli, Elena, Gemma, Sandra, Budriesi, Roberta, Campiani, Giuseppe, Novellino, Ettore, Fattorusso, Caterina, Catalanotti, Bruno, Coccone, Salvatore Sanna, Ros, Sindu, Borrelli, Giuseppe, Persico, Marco, Fiorini, Isabella, Nacci, Vito, Ioan, Pierfranco, Chiarini, Alberto, Hamon, Michel, Cagnotto, Alfredo, Mennini, Tiziana, Fracasso, Claudia, Colovic, Milena, Caccia, Silvio, Butini, Stefania
Published in Journal of medicinal chemistry (11.06.2009)
Published in Journal of medicinal chemistry (11.06.2009)
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