17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes
Bowles, Kathryn R, Pugh, Derian A, Liu, Yiyuan, Patel, Tulsi, Renton, Alan E, Bandres-Ciga, Sara, Gan-Or, Ziv, Heutink, Peter, Siitonen, Ari, Bertelsen, Sarah, Cherry, Jonathan D, Karch, Celeste M, Frucht, Steven J, Kopell, Brian H, Peter, Inga, Park, Y J, Charney, Alexander, Raj, Towfique, Crary, John F, Goate, A M
Published in Molecular neurodegeneration (15.07.2022)
Published in Molecular neurodegeneration (15.07.2022)
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Journal Article
Finding drug targeting mechanisms with genetic evidence for Parkinson's disease -- Mendelian randomization of the druggable genome
Storm, Catherine S, Kia, Demis A, Almramhi, Mona, Bandres-Ciga, Sara, Finan, Chris, Hingorani, Aroon Dinesh, International Parkinson's Disease Genomics Consortium (Ipdgc), Wood, Nicholas W
Published in bioRxiv (24.07.2020)
Published in bioRxiv (24.07.2020)
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Paper
Human-lineage-specific genomic elements: relevance to neurodegenerative disease and APOE transcript usage
Chen, Zhongbo, Zhang, David, Reynolds, Regina H, Gustavsson, Emil K, Sonia García Ruiz, D'sa, Karishma, Fairbrother-Browne, Aine, Vandrovcova, Jana, International Parkinson's Disease Genomics Consortium (Ipdgc), Hardy, John, Houlden, Henry, Gagliano Taliun, Sarah A, Botía, Juan A, Ryten, Mina
Published in bioRxiv (26.05.2020)
Published in bioRxiv (26.05.2020)
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Paper
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability
Reynolds, Regina H, Botia, Juan A, Nalls, Mike A, International Parkinson's Disease Genomics Consortium (Ipdgc), System Genomics Of Parkinson's Disease (Sgpd), Hardy, John, Gagliano, Sarah A, Ryten, Mina
Published in bioRxiv (16.10.2018)
Published in bioRxiv (16.10.2018)
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Paper
Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson's disease
Hampton, Leonard, Blauwendraat, Cornelis, Krohn, Lynne, Faghri, Faraz, Iwaki, Hirotaka, Furgeson, Glen, Day-Williams, Aaron G, Stone, David J, International Parkinson's Disease Genomics Consortium (Ipdgc), Singleton, Andrew B, Nalls, Mike A, Gan-Or, Ziv
Published in bioRxiv (05.10.2018)
Published in bioRxiv (05.10.2018)
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Paper
Genetic variation within genes associated with mitochondrial function is significantly associated with later age at onset of Parkinson disease and contributes to disease risk
Billingsley, Kimberley, Barbosa, Ines A, Bandres-Ciga, Sara, Quinn, John P, Bubb, Vivien J, Deshpande, Charu, Botia, Juan A, Reynolds, Regina H, Zhang, David, Simpson, Michael A, Blauwendraat, Cornelis, Gan-Or, Ziv, J Raphael Gibbs, Nalls, Mike A, Singleton, Andrew B, International Parkinsons Disease Genomics Consortium Ipdgc, Ryten, Mina, Koks, Sulev
Published in bioRxiv (08.12.2018)
Published in bioRxiv (08.12.2018)
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Paper
Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms
Blauwendraat, Cornelis, Heilbron, Karl, Vallerga, Costanza L, Bandres-Ciga, Sara, Rainer Von Coelln, Pihlstrom, Lasse, Simon-Sanchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Siitonen, Ari, Iwaki, Hirotaka, Hampton, Leonard, Noyce, Alastair J, Tan, Manuela, J Raphael Gibbs, Hernandez, Dena G, Scholz, Sonja W, Jankovic, Joseph, Shulman, Lisa M, Lesage, Suzanne, Corvol, Jean-Christophe, Brice, Alexis, Van Hilten, Jacobus J, Marinus, Johan, The 23andme Research Team, Tienari, Pentti, Majamaa, Kari, Toft, Mathias, Grosset, Donald G, Gasser, Thomas, Heutink, Peter, Shulman, Joshua M, Wood, Nicolas, Hardy, John, Morris, Huw R, Hinds, David A, Gratten, Jacob, Visscher, Peter M, Gan-Or, Ziv, Nalls, Mike, Singleton, Andrew, International Parkinsons Disease Genomics Consortium (Ipdgc)
Published in bioRxiv (11.10.2018)
Published in bioRxiv (11.10.2018)
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