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Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
Haycock, Philip C, Burgess, Stephen, Wade, Kaitlin H, Bowden, Jack, Relton, Caroline, Davey Smith, George
Published in The American journal of clinical nutrition (01.04.2016)
Published in The American journal of clinical nutrition (01.04.2016)
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Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study
Hamilton, Fergus W., Thomas, Matt, Arnold, David, Palmer, Tom, Moran, Ed, Mentzer, Alexander J., Maskell, Nick, Baillie, Kenneth, Summers, Charlotte, Hingorani, Aroon, MacGowan, Alasdair, Khandaker, Golam M., Mitchell, Ruth, Davey Smith, George, Ghazal, Peter, Timpson, Nicholas J.
Published in PLoS medicine (30.01.2023)
Published in PLoS medicine (30.01.2023)
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Cellular sources of interleukin-6 and associations with clinical phenotypes and outcomes in pulmonary arterial hypertension
Simpson, Catherine E., Chen, Jenny Y., Damico, Rachel L., Hassoun, Paul M., Martin, Lisa J., Yang, Jun, Nies, Melanie, Griffiths, Megan, Vaidya, Dhananjay, Brandal, Stephanie, Pauciulo, Michael W., Lutz, Katie A., Coleman, Anna W., Austin, Eric D., Ivy, Dunbar D., Nichols, William C., Everett, Allen D.
Published in The European respiratory journal (01.04.2020)
Published in The European respiratory journal (01.04.2020)
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Inflammatory bowel diseases, interleukin-6 and interleukin-6 receptor subunit alpha in causal association with cerebral cortical structure: a Mendelian randomization analysis
Liu, Chunlong, Zhu, Shijie, Zhang, Jian, Ren, Kuiwu, Li, Kangkang, Yu, Jiangtao
Published in Frontiers in immunology (20.04.2023)
Published in Frontiers in immunology (20.04.2023)
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Loss of primary cilia promotes inflammation and carcinogenesis
Paul, Conception, Tang, Ruizhi, Longobardi, Ciro, Lattanzio, Rossano, Eguether, Thibaut, Turali, Hulya, Bremond, Julie, Maurizy, Chloé, Gabola, Monica, Poupeau, Sophie, Turtoi, Andrei, Denicolai, Emilie, Cufaro, Maria Concetta, Svrcek, Magali, Seksik, Philippe, Castronovo, Vincent, Delvenne, Philippe, de Laurenzi, Vincenzo, Da Costa, Quentin, Bertucci, François, Lemmers, Bénédicte, Pieragostino, Damiana, Mamessier, Emilie, Janke, Carsten, Pinet, Valérie, Hahne, Michael
Published in EMBO reports (06.12.2022)
Published in EMBO reports (06.12.2022)
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The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma
Hawkins, Gregory A, Robinson, Mac B, Hastie, Annette T, Li, Xingnan, Li, Huashi, Moore, Wendy C, Howard, Timothy D, Busse, William W, Erzurum, Serpil C, Wenzel, Sally E, Peters, Stephen P, Meyers, Deborah A, Bleecker, Eugene R
Published in Journal of allergy and clinical immunology (01.08.2012)
Published in Journal of allergy and clinical immunology (01.08.2012)
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Polymorphism of Genes Encoding Inflammatory Interleukins and the Risk of Anterior Cruciate Ligament Injury: A Systematic Review and Meta-Analysis
Lorenz, Katarzyna, Mastalerz, Andrzej, Cywińska, Anna, Garbacz, Aleksandra, Maculewicz, Ewelina
Published in International journal of molecular sciences (01.05.2024)
Published in International journal of molecular sciences (01.05.2024)
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Increased IL‐6 and Potential IL‐6 trans‐signalling in the airways after an allergen challenge
Esnault, Stephane, Khosravi, Mehdi, Kelly, Elizabeth A., Liu, Lin Ying, Bochkov, Yury A., Tattersall, Matthew C., Jarjour, Nizar N.
Published in Clinical and experimental allergy (01.04.2021)
Published in Clinical and experimental allergy (01.04.2021)
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GLP-1 Secretion Is Increased by Inflammatory Stimuli in an IL-6–Dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering
Kahles, Florian, Meyer, Christina, Möllmann, Julia, Diebold, Sebastian, Findeisen, Hannes M., Lebherz, Corinna, Trautwein, Christian, Koch, Alexander, Tacke, Frank, Marx, Nikolaus, Lehrke, Michael
Published in Diabetes (New York, N.Y.) (01.10.2014)
Published in Diabetes (New York, N.Y.) (01.10.2014)
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A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis
Esparza-Gordillo, Jorge, Schaarschmidt, Heidi, Liang, Liming, Cookson, William, Bauerfeind, Anja, Lee-Kirsch, Min-Ae, Nemat, Katja, Henderson, John, Paternoster, Lavinia, Harper, John I., Mangold, Elisabeth, Nothen, Markus M., Rüschendorf, Franz, Kerscher, Tamara, Marenholz, Ingo, Matanovic, Anja, Lau, Susanne, Keil, Thomas, Bauer, Carl-Peter, Kurek, Michael, Ciechanowicz, Andrzej, Macek, Milan, Franke, Andre, Kabesch, Michael, Hubner, Norbert, Abecasis, Gonçalo, Weidinger, Stephan, Moffatt, Miriam, Lee, Young-Ae
Published in Journal of allergy and clinical immunology (01.08.2013)
Published in Journal of allergy and clinical immunology (01.08.2013)
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Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease
Jiang, Weiwei, Wu, Na, Wang, Xuemei, Chi, Yujing, Zhang, Yuanyuan, Qiu, Xinyun, Hu, Ying, Li, Jing, Liu, Yulan
Published in Scientific reports (03.02.2015)
Published in Scientific reports (03.02.2015)
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Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra
Crișan, Tania O, Cleophas, Maartje C P, Oosting, Marije, Lemmers, Heidi, Toenhake-Dijkstra, Helga, Netea, Mihai G, Jansen, Tim L, Joosten, Leo A B
Published in Annals of the rheumatic diseases (01.04.2016)
Published in Annals of the rheumatic diseases (01.04.2016)
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Association of the IL‐6R rs2228145 polymorphism with diabetic nephropathy: A case‐control study
Izakovicova, Pavla, Slezakova, Simona, Deissova, Tereza, Poskerova, Hana, Borilova Linhartova, Petra, Dusek, Ladislav, Kankova, Katerina, Izakovicova Holla, Lydie
Published in Journal of diabetes investigation (01.08.2025)
Published in Journal of diabetes investigation (01.08.2025)
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APOε4 is associated with enhanced in vivo innate immune responses in human subjects
Gale, Stephen C., Gao, Li, Mikacenic, Carmen, Coyle, Susette M., Rafaels, Nicholas, Murray Dudenkov, Tanda, Madenspacher, Jennifer H., Draper, David W., Ge, William, Aloor, Jim J., Azzam, Kathleen M., Lai, Lihua, Blackshear, Perry J., Calvano, Steven E., Barnes, Kathleen C., Lowry, Stephen F., Corbett, Siobhan, Wurfel, Mark M., Fessler, Michael B.
Published in Journal of allergy and clinical immunology (01.07.2014)
Published in Journal of allergy and clinical immunology (01.07.2014)
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Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion
Lebrun, Lorène J., Lenaerts, Kaatje, Kiers, Dorien, Pais de Barros, Jean-Paul, Le Guern, Naig, Plesnik, Jiri, Thomas, Charles, Bourgeois, Thibaut, Dejong, Cornelis H.C., Kox, Matthijs, Hundscheid, Inca H.R., Khan, Naim Akhtar, Mandard, Stéphane, Deckert, Valérie, Pickkers, Peter, Drucker, Daniel J., Lagrost, Laurent, Grober, Jacques
Published in Cell reports (Cambridge) (31.10.2017)
Published in Cell reports (Cambridge) (31.10.2017)
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IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
Müller, Nike, Schulte, Dominik M., Türk, Kathrin, Freitag-Wolf, Sandra, Hampe, Jochen, Zeuner, Rainald, Schröder, Johann O., Gouni-Berthold, Ioanna, Berthold, Heiner K., Krone, Wilhelm, Rose-John, Stefan, Schreiber, Stefan, Laudes, Matthias
Published in Journal of lipid research (01.05.2015)
Published in Journal of lipid research (01.05.2015)
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Gene expression in major depressive disorder
Jansen, R, Penninx, B W J H, Madar, V, Xia, K, Milaneschi, Y, Hottenga, J J, Hammerschlag, A R, Beekman, A, van der Wee, N, Smit, J H, Brooks, A I, Tischfield, J, Posthuma, D, Schoevers, R, van Grootheest, G, Willemsen, G, de Geus, E J, Boomsma, D I, Wright, F A, Zou, F, Sun, W, Sullivan, P F
Published in Molecular psychiatry (01.03.2016)
Published in Molecular psychiatry (01.03.2016)
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Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle
Austin, Philip J., Tsitsiou, Eleni, Boardman, Charlotte, Jones, Simon W., Lindsay, Mark A., Adcock, Ian M., Chung, Kian Fan, Perry, Mark M.
Published in Journal of allergy and clinical immunology (01.03.2017)
Published in Journal of allergy and clinical immunology (01.03.2017)
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Direct effects of airborne PM2.5 exposure on macrophage polarizations
Zhao, Qingjie, Chen, Hui, Yang, Tao, Rui, Wei, Liu, Fang, Zhang, Fang, Zhao, Yong, Ding, Wenjun
Published in Biochimica et biophysica acta (01.12.2016)
Published in Biochimica et biophysica acta (01.12.2016)
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