Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes
Indorato, Rose-Laure, Talapatra, Sandeep K, Lin, Fangzhu, Haider, Shozeb, Mackay, Simon P, Kozielski, Frank, Skoufias, Dimitrios A
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed
Skoufias, Dimitrios A, Indorato, Rose-Laure, Lacroix, Françoise, Panopoulos, Andreas, Margolis, Robert L
Published in The Journal of cell biology (19.11.2007)
Published in The Journal of cell biology (19.11.2007)
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Journal Article
Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5
Kozielski, Frank, Skoufias, Dimitrios A, Indorato, Rose-Laure, Saoudi, Yasmina, Jungblut, Peter R, Hustoft, Hanne K, Strozynski, Margarita, Thiede, Bernd
Published in Proteomics (Weinheim) (01.01.2008)
Published in Proteomics (Weinheim) (01.01.2008)
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Journal Article
STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity
Indorato, Rose-Laure, DeBonis, Salvatore, Kozielski, Frank, Garcia-Saez, Isabel, Skoufias, Dimitrios A.
Published in Biochemical pharmacology (15.11.2013)
Published in Biochemical pharmacology (15.11.2013)
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Journal Article
Binding stoichiometry and structural model of the HIV-1 Rev/importin β complex
Spittler, Didier, Indorato, Rose-Laure, Boeri Erba, Elisabetta, Delaforge, Elise, Signor, Luca, Harris, Simon J, Garcia-Saez, Isabel, Palencia, Andrés, Gabel, Frank, Blackledge, Martin, Noirclerc-Savoye, Marjolaine, Petosa, Carlo
Published in Life science alliance (01.10.2022)
Published in Life science alliance (01.10.2022)
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Journal Article
Structure–Activity Relationship of S-Trityl-l-Cysteine Analogues as Inhibitors of the Human Mitotic Kinesin Eg5
DeBonis, Salvatore, Skoufias, Dimitrios A, Indorato, Rose-Laure, Liger, François, Marquet, Bernard, Laggner, Christian, Joseph, Benoît, Kozielski, Frank
Published in Journal of medicinal chemistry (13.03.2008)
Published in Journal of medicinal chemistry (13.03.2008)
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Journal Article
Binding stoichiometry and structural model of the HIV-1 Rev/Importin beta complex
Spittler, Didier, Rose-Laure Indorato, Elisabetta Boeri Erba, Delaforge, Elise, Signor, Luca, Harris, Simon J, Isabel Garcia Saez, Palencia, Andres, Gabel, Frank, Blackledge, Martin, Noirclerc-Savoye, Marjolaine, Petosa, Carlo
Published in bioRxiv (20.11.2021)
Published in bioRxiv (20.11.2021)
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